Notes in Antiarrhythmics

To Subscribe, use this Key

Status	Last Update	Fields
Published	03/27/2023	Antiarrhythmic Classification:Class I - {{c1::inhibit fast Na+ ion channels }} {{c1::Decreases in depolarization rate and conduction velocity}}{{…
Published	03/27/2023	Antiarrhythmic Classification:Class II - {{c1::decrease rate of depolarization}}{{c1::Counteract the effects of endogenous catecholamines}}{{c1::Beta-…
Published	03/27/2023	Antiarrhythmic Classification:Class III- {{c1::inhibit K+ ion channels}}{{c1::Prolong the action potential and refractory period}}Potassium channel bl…
Published	03/27/2023	Antiarrhythmic Classification:Class IV- {{c1::inhibit slow Ca2+ channels}}{{c1::Slows conduction through SA and AV nodes}}{{c1::Calcium channel b…
Published	03/27/2023	Class I Antiarrhythmic Agents{{c1::Na+ channel blockers}} Inhibits fast Na+ channels during {{c1::depolarization (phase 0)}} Cause a {{c1::decrease i…
Published	03/27/2023	Class IA AgentsLengthen both the {{c1::action potential duration}} and {{c1::the effective refractory period}}{{c1::Moderate Na+ channel blockade}} {…
Published	03/27/2023	Class IB Agents{{c1::Shorten the action potential duration and refractory period in normal cardiac ventricular muscle::MOA}}Less {{c1::powerful Na+ ch…
Published	03/27/2023	Class IC AgentsGreatly {{c1::decreases rate of phase 0 depolarization and speed of conduction of cardiac impulses}}Potent {{c1::Na+ channel blockers}}…
Published	03/27/2023	Class II Antiarrhythmic Agents{{c1::Beta-adrenergic antagonists}} Competitive {{c1::antagonize the beta-adrenergic receptors}} Decrease {{c1::the ra…
Published	03/27/2023	Class III Antiarrhythmic Agents{{c1::K+ Channel}} blockers Prolongs {{c1::phase 3 repolarization}} Prolongs {{c1::action potential duration and ERP}…
Published	03/27/2023	Class IV Antiarrhythmic AgentsSlows {{c1::AV nodal conduction primarily by L-type Ca2+ channel antagonism}} Affect {{c1::pacemaker cells at the SA an…
Published	03/27/2023	Class 0 drugsDevelopment of more modern antiarrhythmic drug classification with expanded set of primary receptor targets Ivabradine- a novel class 0 …
Published	03/27/2023	Beta-Blockers SELECTIVE Beta-Blockers NON-SELECTIVE {{c1::Bisoprolol}}{{c1::Propranolol}}{{c1::Esmolol…
Published	03/27/2023	Amiodarone DOSEDose: IV dosing for supraventricular arrhythmias:{{c1::150mg bolus over 10mins, then 1 mg/min for 6 hrs, then 0.5 mg for 18 hrs. Contin…
Published	03/27/2023	Amiodarone Side Effects:PULMMost serious side effect is {{c1::pulmonary fibrosis}} {{c1::5-15}} % occur with chronic therapy Two types of presentatio…
Status	Last Update	Fields