Notes in the drugs start coming and they dont stop coming

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Status	Last Update	Fields
Published	09/29/2023	lidocaine
Published	09/29/2023	nidefipine
Published	09/29/2023	{{c1::sulfonylurea}} stimulates insulin release by blocking {{c1::ATP-sensitive K+ channels}}, facilitating {{c3::Ca2+ channel opening and i…
Published	09/29/2023	{{c1::diazepam}} is an {{c2::antianxiety med}} that {{c2::opens Cl- channels}}
Published	09/29/2023	{{c2::octiatide}} is used to counter {{c1::insulin toxicity}}, and works by {{c1::blocking Ca2+ channels in beta cells}}
Published	09/29/2023	{{c2::octratide}} is a {{c2::somatostatin}} analog, so it works to generally {{c1::reduce endocrine signalling/secretion}}
Published	09/29/2023	{{c1::disulfuram}} is used for {{c2::alcohol aversion therapy}}, and works by {{c1::inhibiting ALDH2}} to {{c2::increase the concentration of acetalde…
Published	09/29/2023	{{c1::fomepizole}} is used in {{c2::methelyne glycol and ethanol poisoning}}, and {{c2::slows down ADH }}
Published	09/29/2023	{{c1::Nitric oxide}} acts a {{c2::vasodilator and systemic anti-inflammatory agent,}} and binds to a GPCR that triggers cGMP formation
Published	09/29/2023	{{c1::glucocorticoids}} bind {{c2::intracellular corticosteroid receptors}} and have {{c2::immunosuppresive, anti-inflammatory, and vasoconstrictive e…
Published	09/29/2023	{{c1::epinephrine}} is binds {{c2::Gs GPCRs}} to trigger {{c1::cAMP formation, PKA activation, and downstream phosphorylation/activation}}
Published	09/29/2023	{{c1::insulin}} binds {{c1::RTKs}} on target cells, causing cross-phosphorylation, activation, and downstream activation of IRS's
Published	09/29/2023	{{c1::metformin}} does a whole bunch of shit, but mainly acts on hepatocytes to {{c2::inhibit glycolisis}}
Published	09/29/2023	{{c1::epinephrine}} is an {{c2::alpha and beta adrenergic receptor (GPCR) agonist}} that {{c1::induces vascular smooth muscle contraction}} and increa…
Published	09/29/2023	{{c1::Isoproterenol}} is a {{c2::beta1 and 2 adrenergic receptor agonist}} that induces increased cardiac contractility, {{c1::increased HR, and perip…
Published	09/29/2023	{{c1::norepinephrine}} is an {{c2::alpha1 and beta2 adrenergic receptor (GPCR) agonist}} that induces systemic vasoconstruction and typically {{c1::re…
Published	09/29/2023	{{c1::dopamine (systemic action)}} is an {{c2::alpha 1, beta1, and beta2 adrenergic agonist}} that has a dose-dependent range of effects: at low dose …
Published	09/29/2023	{{c1::dobutamine}} has mostly {{c2::beta1, but some beta2 adrenergic activity.}} it increases {{c1::cardiac contractility, increases HR, and causes pe…
Published	09/29/2023	{{c1::phenylephrine}} has {{c2::mostly alpha1 adrenergic receptor activity.}} it is {{c1::vasoconstrictive,}} but has {{c3::little to no effect on hea…
Status	Last Update	Fields