Notes in Case 2: Polypharmacy

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Published	06/22/2024	Two common mechanisms of drug-drug interactions are via effects on {{c1::CYP450}} or {{c2::albumin}}
Published	06/22/2024	What two SSRIs are CYP2D6 inhibitors and therefore have many drug interactions?{{c1::FluoxetineParoxetine}}
Published	06/22/2024	The H2 receptor antagonist {{c2::cimetidine}} is a potent {{c3::inhibitor}} of {{c1::cytochrome P-450}} and therefore has multiple drug interactions
Published	06/22/2024	{{c2::Amiodarone}}, a class III antiarrhythmic, is a(n) {{c3::inhibitor}} of {{c1::cytochrome P450}} and thus may have many drug interactions
Published	06/22/2024	Barbiturates are a(n) {{c2::inducer}} of {{c1::cytochrome P450}} and thus may have many drug interactions
Published	06/22/2024	Carbamazepine is a(n) {{c2::inducer}} of {{c1::cytochrome P450}} and thus may have many drug interactions
Published	06/22/2024	Phenytoin is a(n) {{c2::inducer}} of {{c1::cytochrome P450}} and thus may have many drug interactions
Published	06/22/2024	The Beers criteria are used to reduce potential inappropriate prescribing and harmful polypharmacy in the {{c1::geriatric}} population
Published	06/22/2024	Examples of the Beers criteria include drugs that increase the risk of {{c1::hypotension}} (alpha blockers)
Published	06/22/2024	Examples of the Beers criteria include drugs that increase the risk of anti-{{c1::cholinergic}} activity (antihistamines, GI antispasmodics)
Published	06/22/2024	Examples of the Beers criteria include drugs that increase the risk of {{c1::falls}} (benzodiazepines, opioids)
Published	06/22/2024	Examples of the Beers criteria include drugs that increase the risk of {{c1::C. difficile}} infections (PPIs)
Published	06/22/2024	Elderly patients at risk for falls should undergo {{c1::comprehensive risk assessment}} to screen for contributing factors
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