Notes in Gastroenterology

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Published	05/27/2025	Which of the following factors is the strongest contraindication to the use of interferon in the treatment of viral hepatitis?Disease acquisition duri…
Published	05/27/2025	A 20-year-old female presents 48 hours after ingesting 16g of paracetamol. There are no signs of hepatic encephalopathy. Blood tests on admission incl…
Published	05/27/2025	In patients with cirrhosis taking regular opioid agonists can develop acute opioid withdrawal when oxycodone/naloxone is administered. What is the mec…
Published	05/27/2025	Which of the following is a characteristic histopathological feature of alcoholic hepatitis that differentiates it from chronic viral hepatitis? …
Published	05/27/2025	What are the histological patterns of liver injury
Published	05/27/2025	What is the most specific antibody for autoimmune hepatitis?Anti-LKMAnti-SLA/LPAnti-MitochondrialAnti-SMA
Published	05/27/2025	A 42 year old female with T1DM is diagnosed with autoimmune hepatitis based on liver biopsy and blood tests.Bloods shown: mildly deranged LFTs around …
Published	05/27/2025	A nurse sustains a needlestick injury from a patient who is HBV sAg positive, HIV negative, HCV negative. The nurse has previously had serology tests …
Published	05/27/2025	A patient is Hep B SAg -ve , SAb +ve and Hep B C Ab +ve. The risk of reactivation of hepatitis B is highest with which medication?   A.…
Published	05/27/2025	A 56 year old female is newly diagnosed with non Hodgkin’s lymphoma and planned to commence treatment with cyclophosphamide, doxorubicin, vincristine,…
Published	05/27/2025	In a patient with NASH, what is the most important factor causing progression to fibrosis? A. Older age B. Moderate EtOH consumption C.…
Published	05/27/2025	A 58 year old patient was admitted for a bowel obstruction 3 months ago and is currently on TPN. His medications include paracetamol 4g daily & en…
Published	05/27/2025	A 52 year old woman with Childs Pugh C cirrhosis secondary to chronic Hepatitis B re-presents multiple times to hospital with hepatic encephalopathy d…
Published	05/27/2025	What is Rifaximin?
Published	05/27/2025	A 44M with Child-pugh C cirrhosis of the liver is withdrawing from alcohol. Which of the following benzodiazepines is best to manage his withdrawal?Di…
Published	05/27/2025	A 34 male with left sided ulcerative colitis, pre-morbidly on mesalazine 2.4g D is admitted with a flare of ulcerative colitis. He is given IV hydroco…
Published	05/27/2025	A 55 year old gentleman presents with a 3 month history of bloody diarrhoea, abdominal pain, tenesmus, and 6 kg weight loss. His last international tr…
Published	05/27/2025	A young man with a history of stricturing Crohn’s disease had been on treatment with infliximab for 3 years. He developed the following rash over his …
Published	05/27/2025	What are the features of Pyoderma gangrenosum?
Published	05/27/2025	What are the cutaneous EIMs of IBD?
Published	05/27/2025	A 28-year-old male presented two years ago with abdominal pain and profuse diarrhea and was subsequently diagnosed with Crohn’s Disease. Capsule endos…
Published	05/27/2025	A 27-year-old gentleman with Crohn’s Disease is to be commenced on sulfasalazine. What effect will this have on his extra-intestinal bone and joint sy…
Published	05/27/2025	A patient with stricturing Crohn’s Disease managed on azathioprine and infliximab underwent ileal resection, removing 100cm of terminal ileum and subs…
Published	05/27/2025	A 60‐year‐old man presents with pain on defecation over the last two days which is associated with bright red blood on toilet paper. The patient has a…
Published	05/27/2025	Apart from the splenic flexure, what is the other watershed area in the bowel?Ascending colonCaecumHepatic flexureRectosigmoid junction
Published	05/27/2025	A 28-year-old man presents with an itchy symmetrical erythematous vesicular rash with clusters on his shoulders, knees, buttocks and elbows. Which dis…
Published	05/27/2025	What are the features of dermatitis herpetiformis
Published	05/27/2025	The application of faecal transplantation has the best evidence in which of the following conditions?Ulcerative colitisMicroscopic colitisPseudomembra…
Published	05/27/2025	Someone who has radiation for prostate cancer now presents with lower GI bleed. He is haemodynamically stable for now, but is still bleeding profusely…
Published	05/27/2025	A 58-year-old lady taking 20 mg rivaroxaban daily, presents with haematemesis. In addition to resuscitation and commencing a proton pump inhibitor, wh…
Published	05/27/2025	What is the mechanism of action of terlipressin, a vasopressin agonist used in the management of acute variceal bleeding?Splanchnic vasoconstrictionSp…
Published	05/27/2025	A 32 year old alcoholic with a 40 pack year smoking history, on paracetamol, ibuprofen and esomeprazole presents with a GI bleed. Gastroscope revealed…
Published	05/27/2025	57M w bleeding duodenal ulcer secondary to NSAID use. It was successfully treated with endoscopy. He has stopped the NSAID. What is the optimal durati…
Published	05/27/2025	A 46 year old gentleman with a history of recurrent pancreatitis and no other medical problems is discharged from hospital following another episode o…
Published	05/27/2025	A 62‐year‐old female presents with 15 hours of severe epigastric pain. She drinks 70g of alcohol daily. There is no personal or family history of panc…
Published	05/27/2025	A 64 year old man has a history of 2 previous episodes of pancreatitis. He presents with a 4 week history of abdominal pain, anorexia, weight loss and…
Published	05/27/2025	Where are bile acids absorbed to return to the hepatic circulation?A. Ascending colonB. Descending colonC. IleumD JejunumE. Duodenum
Published	05/27/2025	A 65 year old man presents with a 2 week history of jaundice, dark urine and pale stools. He has lost 6 kg in the past 6 weeks and has a reduced appet…
Published	05/27/2025	A lady with asthma is found to have profoundly deranged liver function tests. She drinks approximately 10g of alcohol a day.Bil 75ALT 87GGT 100ALP 300…
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