Notes in Oral Microbiology Lecture 2 Highlighted ONLY

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Published	11/16/2023	There are between 1 million and ___ million bacteria present in 1 ml of saliva, depending upon oral hygiene, frequency of food consumption, and saliva…
Published	11/16/2023	The average child produces between ____ and ___ L of saliva everyday
Published	11/16/2023	The average adult produces between ____ and ____ L of saliva everyday
Published	11/16/2023	______ is produced by Acinar cells and concentrated in the acinar lumen in which Salivary enzymes, ions, and mucins are deposited.
Published	11/16/2023	__________ becomes hypotonic as it is collected into ducts which is lined with ductual cells that facilitate sodium and potassium exchange in addition…
Published	11/16/2023	_________ digests the cell walls of Gram-positive bacteria by breaking the β(1-4) bond between N-acetylmuramic acid and N-acetylglucosamine (NAM-NAG) …
Published	11/16/2023	________ inhibits bacterial growth by binding and sequestering Fe2+ ions, and in the apo (iron free) state can be toxic to bacteria and interfere with…
Published	11/16/2023	_________ are cationic histidine rich proteins that kill Candida albicans and some bacteria. Histatins can bind and infiltrate yeast which results in …
Published	11/16/2023	________ catalyzes the oxidation of thiocyanate (SCN−) to hypothiocyanite (OSCN−) by hydrogen peroxide. Hypothiocyanite oxidizes SH groups in bacteria…
Published	11/16/2023	What antimicrobial component of saliva results in agglutination?
Published	11/16/2023	_________: an antibody, lectin, or other substance that causes agglutination.
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Published	11/16/2023	What is this?•Dimeric IgA •Joining (J) chain •Secretory component (Facilitates trans-cellular transportation)
Published	11/16/2023	What is this?•Polypeptide backbone     •Serine, Threonine, Asparagine rich domains •Oligosaccharide chains      •Glucose…
Published	11/16/2023	___________ can serve as molecular camouflage. A microbial cell is covered by multiple bound salivary agglutinins and mucins. This migh…
Published	11/16/2023	___________ agglutinate microbes. Natural salivary flow causes these aggregates to be swallowed, resulting in clearance of the mic…
Published	11/16/2023	Bacteria usually have a _________ surface charge can inteact with mucins via covalent bridging. Some bacteria have cell surface proteins (lectins/) th…
Published	11/16/2023	ADD What is the benefit of having fixed agglutination? Colonization may have illustrated co-evolution?
Published	11/16/2023	_______________ is imbedded in the salivary pellicle and is bound by S. mutans
Published	11/16/2023	The salivary pellicle is initially protective of teeth but as a downside it facilitates what?
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Published	11/16/2023	The Critical pH is pH 5.5. What does this mean?
Published	11/16/2023	S. mutans uses what to convert sucrose into glucans and fructans? What is the consequence of this?
Published	11/16/2023	S. mutans uses what kind of fermentation and what does this mean?
Published	11/16/2023	What is the strongest acid S. mutans makes?
Published	11/16/2023	S. mutans is gram ___, ____ morphology, forms_____.
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Published	11/16/2023	What does F1F0 ATPase do?
Published	11/16/2023	What does fabM do?
Published	11/16/2023	Greater membrane saturation = what?
Published	11/16/2023	What do Dcp/Ffh/Dgk do?
Published	11/16/2023	What is aciduricity?
Published	11/16/2023	The critical pH of fluorapatite is 4.5. This is much lower than hydroxyapatite. What does this mean?
Published	11/16/2023	Not all bacteria are equally affected by _______. Lactobacillus sp. Often require higher rates of fluoride to be as effective as observed in S. mutans…
Published	11/16/2023	Describe why flouride has antimicrobial properties
Published	11/16/2023	Describe how silver has antimicrobial properties.
Published	11/16/2023	Bacteria that are killed by SDF further act as a ____ for silver ions
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Published	11/16/2023	_______ competes for binding on salivary pellicle and inhibits normal function of glucosyltransferases.
Published	11/16/2023	Epigallocatechin gallate (EGCG) is a type of what?
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Published	11/16/2023	How does EGCG inhibit caries?
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