Notes in 06 Malignancy

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Published 02/10/2024 {{c2::Squamous Carcinoma}} of the Oesophagus occurs in {{c1::proximal}} and {{c1::middle third}} of oesophagus
Published 02/10/2024 {{c2::Adenocarcinoma}} of the Oesophagus occurs in {{c1::distal}} oesophagus
Published 02/10/2024 Infection with H. pylori increases the risk of {{c1::stomach}} cancer
Published 02/10/2024 Histopathology of Stomach cancer is {{c1::Adenocarcinoma}}
Published 02/10/2024 The most common inherited syndromes that increase the risk of Ampullary Cancer are {{c2::familial adenomatous polyposis}}
Published 02/10/2024 Liver Cancer includes {{c1::Hepatocellular carcinoma (HCC)}} and {{c1::Cholangiocarcinoma (Bile duct Cancer)}}
Published 02/10/2024 Investigations of Liver cancer {{c1::Alpha-fetoprotein}} is a tumour marker for hepatocellular carcinoma. {{c1::CA19-9}} is a tumour ma…
Published 02/10/2024 {{c1::Alpha-fetoprotein}} is a tumour marker for {{c2::hepatocellular carcinoma}}{{c1::CA19-9}} is a tumour marker for {{c2::cholangiocarcin…
Published 02/10/2024 {{c1::Colorectal Cancer}} is cancer of the colon and rectum and is the third most common malignancy
Published 02/10/2024 Three molecular aspects of adenocarcinoma that lead to cell growth, proliferation, apoptosis:[1] Activation of {{c1::oncogene}} - k-ras, c-myc [2] Los…
Published 02/10/2024 The majority of colorectal cancers arise from pre-existing {{c1::Polyps/Adenomas}}
Published 02/10/2024 Types of Colorectal Cancers are {{c1::right}}-sided which are ({{c2::Exophytic-Polypoid}}) and {{c1::left}}-sided which are ({{c2::Annular}}…
Published 02/10/2024 Patients with conditions like {{c1::Familial adenomatous polyposis (FAP)}} or {{c1::Hereditary nonpolyposis colorectal cancer (HNPCC)}} are geneticall…
Published 02/10/2024 Investigations of Colorectal CancerThe {{c1::Bowel Cancer Screening Program}} which aims to detect pre-malignant adenomas/early cancers in the general…
Published 02/10/2024 In Scotland, Colorectal Cancer Screening is done between the age {{c1::50-74}} every {{c1::2}} years
Published 02/10/2024 {{c1::Faecal Immunochemical Testing (FIT)}} — 2017 ‒ is the Bowel Cancer Screening Program currently used in 2021 for people between Age 50-…
Published 02/10/2024 High Risk Groups that undergo Bowel Cancer Screening Program are patients with:[1] {{c1::FAP (familial adenomatous polyposis)}}[2] {{c1…
Published 02/10/2024 The Investigation of choice for Colorectal Cancer is {{c1::colonoscopy}} or {{c1::sigmoidoscopy}}
Published 02/10/2024 The golden standard imaging investigation for Colorectal Cancer is {{c1::CT colonography via virtual colonoscopy}} 
Published 02/10/2024 {{c1::Surgical resection}} is usually treatment of choice in CRC if no metastatic disease is present and patient is fit
Published 02/10/2024 The extent of Colorectal Cancer is assessed using {{c1::Dukes}} staging system and {{c1::TNM}} system.
Published 02/10/2024 Investigations of Rectal and Anal Cancer{{c1::Rectal examination}}  {{c1::Colonoscopy}} + {{c1::biopsy}} {{c1::CT colonoscopy}}
Published 02/10/2024 {{c1::Haemangiomas}} are common benign tumours of the liver which are collections of blood.
Published 02/10/2024 {{c1::Focal nodular hyperplasia}} is a benign liver tumour made of fibrotic tissue related to oestrogen. 
Published 02/10/2024 {{c1::Dysplasia}} is uncontrolled division of cells, can be either high or low grade, which is a precursor to malignancy
Published 02/10/2024 {{c1::Neoadjuvant}} therapy is given before the main surgery to shrink a tumour if there are complications, i.e. removal of rectum in rectal cancer co…
Published 02/10/2024 {{c1::Adjuvant}} therapy is additional cancer treatment given after the primary treatment to lower the risk that the cancer will come back
Published 02/10/2024 Ileostomy stomas always have a {{c1::spouted}} appearance compared to Colostomy stomas.
Published 02/10/2024 Treatment of most GI cancers is {{c1::surgical excision}} if diagnosed early
Published 02/10/2024 {{c1::Ultrasound}} is the gold standard imaging for identifying Liver tumours
Published 02/10/2024 Presentation of {{c2::Oesophageal Cancer}} {{c1::Progressive dysphagia}} {{c1::Weight loss and anorexia}} {{c1::Older age}}
Published 02/10/2024 {{c2::Painless jaundice}} is a sign of {{c1::Pancreatic Cancer}} and {{c1::Cholangiocarcinoma}}
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