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05LE Mechanics of breathing,pressures and work
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Published
01/07/2025
What is ventilation?
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01/07/2025
What is respiration?
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What is cellular respiration?
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Where does intrapleural space exist?
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What is tidal volume?What is tidal volume at rest?
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What is normal respiratory rate?
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What is minute ventilation?
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What is alveolar ventilation?
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What happens to the:-diaphragm-Scalene musclesduring inspiration?
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What are the accessory muscles involved in forced inspiration?
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What type of process is inspiration?>What does this mean?
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Describe what happens when the inspiratory muscles contract.(4)- expansion of?- leading to an increase of?- decrease in which pressures?- what does th…
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What must happen for flow of air into the lungs?
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What happens to the pressures at the end of inspiration?
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What type of process is expiration?Why does expiration occur?
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What happens to the pressures during expiration?intrapleural and alveolar pressures increase or decrease?
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What does forced expiration require? (3)--What happens to Intrapleural pressure?
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What determines whether air enters or leaves the lungs?
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Describe Intrapleural pressure(3)pleural space is?Slightly what due to recoil of chest and lungs away from each other?stops lungs from?
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Under physiological conditions (quiet breathing):-The {{c1::transmural pulmonary}} pressure is always {{c2::positive}}-The {{c1::intrapleural}} pressu…
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What is the intra-pulmonary/alveolar pressure at the end of inspiration and expiration?
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For a given lung volume, the {{c1::transmural pulmonary}} pressure is {{c1::equal and opposite}} to the {{c1::elastic recoil}} pressure of the lung
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What is the purpose of transmural pulmonary pressure?
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Define functional residual capacity
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Describe what happens to the-respiratory muscles-lungs-chest wallat Functional residual capacity (FRC)(2)
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What is the volume of air at FRC determined by?
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FRC is affected by lung diseases, give two examples of diseases that affect FRC and explain them.
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Define Impedance
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When our respiratory muscles contract for inspiration, what force must be overcome?
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Define compliance
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What type of structure are the lungs?What are they made of?
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Define distending pressure
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Describe what this graph shows:Define the key terms
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What is a dynamic pressure-volume loop obtained from?
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What is the airflow and alveolar pressures at the end of inspiration/expiration?
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What is hysteresis?difference between which curves? for what?lung is less compliant at ... volumes
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Describe Laminar airflow (4)
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Describe Turbulent airflow- at what points in the aiways is there turbulent flow?- when does turbulent flow occur? responsible for?
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Where does airway resistance originate from?What does airway resistance affect?
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How do we calculate Airflow?Describe the relationship of airflow and viscosity
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What are the factors affecting laminar flow(airway resistance)? (4)-Parasympathetic nerve supply affects? -B-adrenergic receptors ca…
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Describe how bronchoconstriction & bronchodilation affect airflowrefer to radius, resistance, airflow
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What are the factors that may cause increased airway resistance in asthma? (4)
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Increased airflow resistance in COPD can be as a result of what 2 things?
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Describe surface tension (3)>Caused by what in alveoli?>Forces between molecules at surfaces of alveolus creates a tension which will shrin…
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Describe Atelectasis
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What are patient factors affecting surface tension?
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What is a pulmonary surfactant?
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What are pulmonary surfactants produced by?
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What is a key property of pulmonary surfactants?
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Why is pulmonary surfactant important? (4)
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what does surface tension do in relation to capillaries
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01/07/2025
Describe neonatal respiratory distress syndrome
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Tidal Volume
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What is the following definition reffering to?Chest wall exerts a distending pressure on the pleural space which is transmitted to the alveoli to incr…
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Frictional Airway Resistance and Elastic Resistance to stretching of the lungs and chest wall
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Impedance
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When the pressure difference across the lung is equal to the alveolar-intrapleural pressure
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At higher volumes, is the lung more or less compliant?
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Describe compliance in interstitial fibrosis vs emphysema.
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Centre layers move faster than outer ones forming a cone-shaped front
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Friction between air and mucosa generates...
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What do type II pneumocytes produce?
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Increased airflow resistance as a result of: -Bronchoconstriction -chronic mucosal hypertrophyis a…
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01/07/2025
Increased airway resistance caused by: -Bronchoconstriction -mucosal oedema (swelling) …
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01/07/2025
What happens to the:-intercostal muscles-ribsduring inspiration?
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01/07/2025
Why does intrapleural pressure not equilibriate with the atmosphere?
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Why is intrapleural pressure slightly sub-atmospheric? (3)What does this help prevent? (1)
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What is the transpulmonary pressure the pressure difference between?
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01/07/2025
What structures create the transmural pulmonary pressure (Ptp)?
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What is lung compliance?
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What is the elastic recoil of the lungs balanced by?
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Relationship between airway resistance and 4th power of the radius
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What can Airway resistance be assessed from?
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Why is inspiration shorter than expiration?
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When is lung less compliant?
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