Notes in 13 Volatile Anesthetics 2 Pharmacodynamics

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Published	12/13/2023	Halothane and sevoflurane slow {{c2::SA}} node conduction, increasing the risk of {{c1::bradyarrhythmias}}.
Published	12/13/2023	What patients are at particularly high risk for halothane hepatitis?{{c1::Multiple exposures to halothane in short intervals.}}{{c2::Middle-aged obese…
Published	12/13/2023	The fulminant form of halothane hepatitis is characterized by {{c1::liver/centrilobular necrosis}}.
Published	12/13/2023	With the exception of {{c2::desflurane}}, most volatile anesthetics are broncho{{c1::dilators}}.
Published	12/13/2023	{{c2::Isoflurane::inhaled anesthetic}} is unique because it will not increase cerebral blood flow at {{c1::low::high/low}} MAC values.
Published	12/13/2023	The blood-gas partition coefficient at 37°C for isoflurane is {{c1::1.4}}.
Published	12/13/2023	{{c2::Unconsciousness}} from volatile anesthetics is probably mediated at the level of the {{c3::cortex}}, {{c3::thalamus}}, and {{c3::reticular …
Published	12/13/2023	The vapor pressure of isoflurane at 20°C is {{c1::240}} mmHg.
Published	12/13/2023	The vapor pressure of halothane at 20°C is {{c1::243}} mmHg.
Published	12/13/2023	The vapor pressure of desflurane at 20°C is {{c1::681}} mmHg.
Published	12/13/2023	The vapor pressure of sevoflurane at 20°C is {{c1::160}} mmHg.
Published	12/13/2023	The maintenance MAC of desflurane is {{c1::2}} to {{c1::7}}%.
Published	12/13/2023	{{c1::Nitrous oxide::inhaled anesthetic}} alters the immune system by affecting the chemotaxis and motility of {{c2::polymorphonuclear leukocytes}}.&n…
Published	12/13/2023	In an obstetric setting, {{c2::sevoflurane}} and {{c2::desflurane}} inhibit the frequency and amplitude of {{c1::myometrial contractions}}.
Published	12/13/2023	Volatile anesthetics can be used to relax the uterus when removing a {{c1::retained placenta}}.
Published	12/13/2023	{{c2::Alkane}} inhaled anesthetics have a {{c1::R-H}} structure.
Published	12/13/2023	The boiling point of desflurane is {{c1::22}}°C.
Published	12/13/2023	The molecular weight of sevoflurane is {{c1::200}} g/mol.
Published	12/13/2023	The molecular weight of nitrous oxide is {{c1::44}} g/mol.
Published	12/13/2023	The brain-blood partition coefficient of desflurane is {{c1::1.3}}
Published	12/13/2023	The muscle-blood partition coefficient of sevoflurane is {{c1::3.1}}
Published	12/13/2023	The fat-blood partition coefficient of sevoflurane is {{c1::47.5}}
Published	12/13/2023	Xenon produces slight {{c1::decreases}} in the heart rate.
Published	12/13/2023	What three drugs cause a left shift in the PaCO2 / minute ventilation curve?{{c1::Salicylates}}, {{c1::aminophylline}}, and {{c1::doxapram}}
Published	12/13/2023	Volatile anesthetics undergo biotransformation into {{c2::reactive oxygen species}} that impair {{c1::glomus type I}} cells.
Published	12/13/2023	CMRO2 (cerebral metabolic rate) is dependent on {{c1::electrical activity::60%}} and {{c2::cellular homeostasis::40%}}.
Published	12/13/2023	Which volatile anesthetic increases CSF absorption?{{c1::Isoflurane}}
Published	12/13/2023	What anesthetic drug increases the amplitude of evoked potentials?{{c1::Ketamine}} and {{c2::Etomidate}}
Published	12/13/2023	What type of evoked potentials are most resistant to anesthetic effects?{{c1::Brain auditory evoked potentials}}
Published	12/13/2023	What type of evoked potentials are most sensitive to anesthetic effects?{{c1::Visual evoked potentials}}
Published	12/13/2023	Does desflurane contain a chiral carbon?{{c1::No}}
Published	12/13/2023	Does isoflurane contain a chiral carbon?{{c1::No}}
Published	12/13/2023	How does fluorination affect the vapor pressure of an anesthetic?{{c1::Increased}}
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