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Hematopoiesis (11/3)
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Status
Last Update
Fields
Published
11/11/2023
Granulocytes
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11/11/2023
{{c1::Plasma}} ‒ liquid portion of blood when clotting is prevented
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{{c1::Serum}} ‒ liquid portion of blood after clotting has occurred
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Hematopoietic tissues
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{{c1::Lymphopoiesis}} ‒ B & T lymphocytes; NK cells
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{{c1::Myelopoiesis}} ‒ granulocyte, monocyte; platelet/thrombocyte; and RBC production
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{{c1::Granulopoiesis}}‒ {{c2::neutrophil}}, {{c2::esosinophil}}, and {{c2::basophil}} production
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{{c1::Thrombopoiesis / thrombogenesis}} ‒ thrombocyte (platelet) production
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11/11/2023
{{c1::Erythropoiesis}}‒ RBC production
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11/11/2023
Hematopoiesis ~17 days → 2-3 months ⇒ {{c1::Yolk Sac}}
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11/11/2023
Compartments of Bone Marrow
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Major populations of cells in Hematopoietic tissue (3)
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{{c2::{{c1::Basophils}}}}, {{c3::{{c1::Platelets}}}} and {{c3::{{c2::Erythrocytes}}}} are all derived from a common progenitor cell
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{{c2::{{c1::Neutrophils}}}}, {{c3::{{c1::Monocytes}}}} and {{c3::{{c2::Eosinophils}}}} are all derived from a common progenitor cell
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11/11/2023
A normal Myeloid-to-Erythroid (M:E) ratio is {{c1::2.1}} to {{c1::4.1}}
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11/11/2023
The percent cell distribution of fat cells in bone marrow is roughly {{c1::age in years}}
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11/11/2023
Molecular markers {{c1::c-kit}} & {{c1::Thy-1}} are used to identify {{c2::hematopoeitic stem cells (HSC)}}
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11/11/2023
{{c1::CD34+}} is used to identify HSCs for transplant
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11/11/2023
3 Major groups of Hematopoietic growth factors
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11/11/2023
{{c1::Colont Stimulating Factor (CSF)}} cause committed precursors & late precursors to grow in vitro in clusters or colonies
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11/11/2023
Normal, fully mature neutrophils have {{c1::3}}-{{c1::5}} nuclear lobes
Published
11/11/2023
Hematopoiesis 2-3 months → 2ⁿᵈ trimester ⇒ {{c1::Embryonic Mesoderm}}
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11/11/2023
Hematopoiesis ~6wks → 7m ⇒ {{c1::Liver}}
Published
11/11/2023
Hematopoiesis~7-8 months ⇒ {{c1::Thymus}}
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11/11/2023
Hematopoiesis~5 months → birth ⇒ {{c1::Bone Marrow}}
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11/11/2023
{{c2::HSCs::cell type}} & {{c2::progenitor cells::cell type}} express the transmembrane protein {{c1::CD34}}
Published
11/11/2023
Locations of extramedullary hematopoiesis
Status
Last Update
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