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Published	11/05/2024	total iron in the body
Published	11/05/2024	Iron is distributed in the human body in what Forms of
Published	11/05/2024	{{c1::65-75}}% of iron in the body is in hemoglobin
Published	11/05/2024	iron fixed in tissue is stored in molecules and enzymes such as
Published	11/05/2024	labile tissue iron is storred in the form of {{c1::hemosiderin (small amount)}} and {{c1::ferritin}}
Published	11/05/2024	iron is transported in plasma in the form of {{c1::transferrin}}
Published	11/05/2024	average daily iron requirement is {{c1::15-20}} mg/day
Published	11/05/2024	iron containing proteins which are not heme
Published	11/05/2024	iron homeostasis is controlled by control of {{c1::absorption}} (absorption/loss)
Published	11/05/2024	types of iron sources
Published	11/05/2024	Delete
Published	11/05/2024	heme is absorbed by intestinal cells in the duodenum by a {{c1::heme carrier protein 1 (HCP1)}}
Published	11/05/2024	fate of heme absorbed into enterocytes
Published	11/05/2024	how cooking increases iron absorbed from non heme iron
Published	11/05/2024	form of iron in non-heme iron
Published	11/05/2024	Fe3+ in diet is reduced to Fe2+ by {{c1::ferrireductase}} enzyme
Published	11/05/2024	acids that facilitate reduction of ferric iron
Published	11/05/2024	ferrous iron in the GIT is transported into enterocytes via a {{c1::divalent metal transporter (DMT-1)}}
Published	11/05/2024	the divalent metal transporter (DMT-1) of enterocytes transportes {{c1::ferrous iron}} and a {{c1::proton}}
Published	11/05/2024	source of hepcidin (organ of origin)
Published	11/05/2024	function of hepcidin
Published	11/05/2024	how hepcidin work?
Published	11/05/2024	function of ferroportin protein
Published	11/05/2024	hepcidin is chemically formed of a {{c1::peptide}}
Published	11/05/2024	fate of iron in enterocytes when it's not needed
Published	11/05/2024	{{c1::ferroxidase}} turns Fe2+ to Fe3+ in enterocytes
Published	11/05/2024	what happens to stored iron in enterocytes if it's not absorped into the blood
Published	11/05/2024	why can't ferrous iron in enterocytes enter the blood in presence of hepcidin
Published	11/05/2024	ferroportin is also called the {{c1::basolateral membrane protein}} of enterocytes
Published	11/05/2024	fate of ferrous iron in enterocytes when iron is needed
Published	11/05/2024	transferrin can hold {{c1::2}} ferric iron atoms
Published	11/05/2024	{{c1::copper-containing membrane protein (hephaestin)}} turns Fe2+ to Fe3+ after iron is transported by ferroportin into the blood
Published	11/05/2024	what decreases hepcidin in iron deficiency
Published	11/05/2024	hepcidin deficiency results in {{c1::iron overload}}
Published	11/05/2024	most important factor for Iron absorption
Published	11/05/2024	factors increasing iron absorption
Published	11/05/2024	factors decreasing iron absorption
Published	11/05/2024	total body iron is regulated by absorption at the {{c1::duodenal}} section of the GIT
Published	11/05/2024	Apotransferrin chemically is formed of {{c1::glycoproteins}}
Published	11/05/2024	transferrin is synthesized in the {{c1::liver}}
Published	11/05/2024	folic acid consists of base {{c1::pterdine}} attached to {{c2::PABA (p-aminobenzoic acid)}} and {{c2::glutamic acid}}
Published	11/05/2024	{{c1::methylmalonyl-CoA mutase}} needs {{c2::deoxyadenosylcobalamin}} as a cofactor
Published	11/05/2024	form of folic acid found in yeast and grean leafy vegetables
Published	11/05/2024	active form of folic acid
Published	11/05/2024	metabolic role of tetradydrofolate
Published	11/05/2024	tetrahydrofolate is essential for synthesis of {{c1::choline}}, {{c1::serine}}, {{c1::glycine}}, {{c1::methionine}}, and {{c1::purines}}
Published	11/05/2024	methotrexate is an inhibitor of {{c1::dihydrofolate reductase}}
Published	11/05/2024	requirement of folate per day
Published	11/05/2024	Vitamin B12 is formed of a {{c1::tetrapyrrole (corrin ring)}} ring and a {{c1::cobalt ion}} in the center
Published	11/05/2024	cause of red color of vitamin B12
Published	11/05/2024	forms of Vitamin B12 based on group attached to cobalt
Published	11/05/2024	can vitamin B12 be found in a plant-based diet
Published	11/05/2024	forms of Vitamin B12 in the liver
Published	11/05/2024	requirements of Vitamin B12 per day
Published	11/05/2024	folate in diet is in the form of {{c1::dihydrofolate}} (dihydrofolate/tetrahydrofolate)
Published	11/05/2024	Vitamin B12 stores in the liver can stay up to {{c1::6 years}}
Published	11/05/2024	Vitamin B12 is converted to what intracellularly
Published	11/05/2024	Vitamin B12 is absorbed in the {{c1::lower ilium}} (section in GIT)
Published	11/05/2024	Vitamin B12 needs {{c1::intrinsic factor}} released from {{c2::parietal}} cells to be absorbed
Published	11/05/2024	{{c1::intrinsic factor}} protects Vitamin B12 from digestion in the GIT
Published	11/05/2024	Vitamin B12 is transported across the intestinal mucosa by {{c1::endocytosis}}
Published	11/05/2024	Vitamin B12 is transported in Blood bound to {{c1::transcobalamin}}
Published	11/05/2024	methylmalonyl CoA mutase converts methylmalonyl CoA into {{c1::succinyl CoA}}
Published	11/05/2024	metabolic function of methylcobolamin
Published	11/05/2024	Explain the folate trap
Published	11/05/2024	cause of neurological symptoms in Vitamin B12 deficiency
Published	11/05/2024	neurological symptoms in Vitamin B12 deficiency could be secondary to deficiency in {{c1::methionine}}
Published	11/05/2024	normally only {{c1::35}}% of transferrin in blood is saturated
Published	11/05/2024	what does Total iron binding capacity (TIBC) represent
Published	11/05/2024	transferrin is taken up by the cell by {{c1::receptor mediated endocytosis}}
Published	11/05/2024	how is iron dissociated from transferrin in the cell
Published	11/05/2024	transferrin receptor gene expression and ferritin is regulated by {{c1::iron regulatory proteins}} and {{c1::iron responsive elements}} that depend on…
Published	11/05/2024	where is iron stored? (site in body)
Published	11/05/2024	how much ferric ions can be taken up by apoferritin
Published	11/05/2024	when is plasma ferritin high in blood
Published	11/05/2024	when is plasma ferritin low in blood
Published	11/05/2024	ferritin is water {{c1::soluble}} (soluble/insoluble)
Published	11/05/2024	hemosiderin is water {{c1::insoluble}} (soluble/insoluble)
Published	11/05/2024	normal adults loss {{c1::1-2}} mg/day of iron
Published	11/05/2024	how is iron excreted in normal adults
Published	11/05/2024	lethal dose of iron in children
Published	11/05/2024	lethal dose of iron in adults
Published	11/05/2024	hereditary hemochromatosis is due to mutations to the {{c1::high iron (HFE)}} gene
Published	11/05/2024	treatment of hereditary hemochromatosis
Published	11/05/2024	other names for folic acid
Status	Last Update	Fields