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12IntroToEBM
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moon-ack-harry-oven-friend-uranus
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Three components make it a unique and relevant model of EBM practice:1. {{c1::Clinical Judgement }}2. {{c1::Relevant Scientific Evidence}}3.…
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Highest form of evidence for primary studies {{c1::RCT}}
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Higher form of evidence exists amongst {{c1::secondary evidence studies::Study Class}} where the forms of research methodology Involves synthesizing e…
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Evidence-based medicine is rooted in secondary evidences that can be in the form of1. {{c1::Systematic reviews}}2. {{c2::Meta-analysis}}3. {{c3::Clini…
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5s Hierarchy of Evidence focuses on the different {{c1::secondary::primary/secondary}} research more than {{c1::primary::primary/secondary}} research,…
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[Hierarchy of Evidence]Lowest layers including {{c1::synopses}}, {{c1::syntheses}}, and {{c1::original studies }} most often examine only {{c2::1…
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[Hierarchy of Evidence]{{c1::Syntheses}} — synthesized primary studies
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[Hierarchy of Evidence]{{c1::Synopses}} — evidence-based journal abstract of various critically appraised journal articles
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[Hierarchy of Evidence]{{c1::Summaries}} — best available evidence from the lower layers to provide a full-range of evidence concerning management opt…
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[Hierarchy of Evidence]{{c1::Systems}} — theoretical research at present that integrate computerized decision-making
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Search (systematic)Appraisal (best available evidence)Synthesis (summarizing)Analysis (recommending)
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{{c2::Preferred Reporting of Items in Systematic Review and Meta-analyses (PRISMA)}} - The evidence-based {{c1::minimum}} set of items for reporting i…
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PRISMA consists of {{c1::27}} items deemed essential for transparent reporting of a systematic review.
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[Systematic Review vs. Meta-analyses]Identify and critique relevant research studies{{c1::Systematic review}}
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[Systematic Review vs. Meta-analyses]Identify relevant research studies using a defined protocol{{c1::Meta-analyses}}
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[Systematic Review vs. Meta-analyses]Discuss factors that may explain heterogeneity{{c1::Systematic review}}
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[Systematic Review vs. Meta-analyses]Statistically test study heterogeneity and investigate explanatory variables{{c1::Meta-analyses}}
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[Systematic Review vs. Meta-analyses]Synthesize the knowledge{{c1::Systematic review}}
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[Systematic Review vs. Meta-analyses]Statistically summarize results to obtain an overall estimate of treatment effect{{c1::Meta-analyses}}
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A key distinguishing trait of meta-analytic papers:{{c1::Statistical summary of reviewed studies}}, not seen in systematic reviews
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[Recommended structures of review questions]Effectiveness/Therapy/Intervention:{{c1::PICO (Patient/Population, Intervention, Comparator, Outcome)}}
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[Recommended structures of review questions]Diagnostic Accuracy:{{c1::PIRD (Population, Index, Reference, Diagnosis)}}
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[Recommended structures of review questions]Prevalence:{{c1::CoCoPop (Condition, Control, Population)}}
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[Recommended structures of review questions]Etiology & Risk:{{c1::PEO (Population, Exposure, Outcome)}}
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[Step of Evidence-Based Practice]Clinical decision required{{c1::Assessment}}
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[Step of Evidence-Based Practice]Focused question (PICO){{c1::Ask}}
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[Step of Evidence-Based Practice]Developing a comprehensive search strategy. Goal is to get all possible sources of information related to the questio…
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[Step of Evidence-Based Practice]Looking for threats to internal validity. Critically appraise the evidence for validity, impact, applicability, and r…
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[Step of Evidence-Based Practice]Integrate the evidence into your clinical decision making. Synthesize the findings and analyze them in light of the r…
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[Step of Evidence-Based Practice]Evaluate all steps and seek ways to improve next time{{c1::Audit}}
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