Notes in IA. Bacterial Infections [Chlamydia to Neisseria]

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Status	Last Update	Fields
Published	02/17/2025	Clinical Presentation of Chlamydial Infections1. {{c5::Urethritis}} 2. {{c4::Cervicitis}} 3. Proctitis 4. Conjunctivitis 5. Salpingitis 6. {{c3::Prost…
Published	02/17/2025	Serotypes of C. trachomatisSerovars A, B, Ba, & C  = {{c1::Ocular Trachoma}}Serovars D-K = {{c2::Oculogenital Infections}}Serovars L1, L2, L3…
Published	02/16/2025	Macroscopic feature: Halberstaedter Prowazek bodies
Published	02/17/2025	Progresses to scarring and blindness
Published	02/17/2025	Replication cycle of ChlamydiaEB attaches to receptors of plasma membrane – usually in {{c2::columnar}} epithelial cells. Enters via {{c1::endoc…
Published	02/19/2025	Chlamydia● Obligate intracellular parasite● Gram {{c1::(-)}}● Lacks {{c3::cell wall and peptidoglycan}}● {{c2::Non-motile::Motile/Non-motile}}● No pil…
Published	02/17/2025	Neisseria● Gram {{c1::(-)}} Diplococci● Pathogenic for humans● {{c4::Non-motile::motile/non-motile}}● Oxidase {{c2::(+)}}● All Neisseria species with …
Published	02/17/2025	Sugar Utilization TestNeisseria {{c3::meningitidis}} = Ferments {{c2::Glucose And Maltose}}Neisseria {{c4::gonorrhea}} = Ferments {{c1::Glucose Only}}
Published	02/17/2025	Neisseria Virulence Factors{{c1::Pili}} - attachment and antiphagocytic, most important virulence factorOuter membrane protein, {{c2::POR}} - prevents…
Published	02/17/2025	Neisseria: Mode of transmission● {{c2::Sexual contact}}● {{c1::Vertical transmission}} - across the placenta,  breast milk, direct contact during…
Published	02/17/2025	Neisseria: Diagnostics● {{c1::Culture}} on Selective Media - Most sensitive diagnostic method● {{c2::NAAT (Nucleic Acid Amplification Test)}} - Gold s…
Published	02/17/2025	Neisseria: Treatment■ {{c2::Ceftriaxone}}■ If with Chlamydia co-infection → {{c1::Doxycycline}}
Published	02/16/2025	Appearance of discharge of Neisseria: {{c1::Yellow, creamy pus}}, and painful urination
Published	02/16/2025	Most common cause of urethritis
Published	02/17/2025	Neisseria Virulence Factors: - attachment and antiphagocytic, most important virulence factor
Published	02/17/2025	Neisseria Virulence Factors: Outer membrane protein - prevents phagolysosomal fusion
Published	02/17/2025	Neisseria Virulence Factors: Outer membrane protein - for attachment of bacteria to mucosal surface
Published	02/17/2025	Neisseria Virulence Factors: Outer membrane protein - Induces antibody protection with inhibits antibody killing effect
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