Notes in 02. Pulm HTN

To Subscribe, use this Key

Status	Last Update	Fields
Published	06/26/2023	what is pulmonary hypertension? group of dz's of pulmonary {{c1::vasculature}} resulting from increased pressure in the pulm circulation&nbs…
Published	06/26/2023	normal mPAP at rest is {{c1::14 +- 3}} with upper limit of {{c1::20}}
Published	06/26/2023	{{c1::pulmonary}} vs systemic circulation
Published	06/26/2023	{{c1::determinants}} of PA pressure and flow
Published	06/26/2023	the definition of PAH is based on {{c1::right heart catheterization}} with a value of mPAP >{{c1::20mmHg}}
Published	06/26/2023	WHO groups and pulmonary HTN Group 1 → {{c1::PAH}}Group 2 → {{c1::Left heart related}}group 3 → {{c2::Lung/hypoxia related}}group …
Published	06/26/2023	pulmonary hyptertension is an mPAP {{c1::>20}} vs pulmonary arterial hypertension (PAH) with the following values → mPAP >20, PAWP <{{c1…
Published	06/26/2023	Cor pulmonale is defined as an alteration in the structure and function of the {{c1::right ventricle}} of the heart caused by a primary disorder …
Published	06/26/2023	PAH is more common in {{c1::women}} than {{c1::men}} and mean age at diagnosis is {{c1::50 years old}}
Published	06/26/2023	PAH epidemiology → {{c1::schistomomiasis}}
Published	06/26/2023	the major predisposing gene in PAH is {{c1::BMPR2}} with over 300 mutations being identified
Published	06/26/2023	PAH {{c1::drug}} induced
Published	06/26/2023	the most prevalent connective tissue disease associated with PAH is {{c1::scleroderma}} ; results in a poorer prognosis and PAH being the leading…
Published	06/26/2023	prognosis of untreated PAH is poor, even in {{c1::mildly}} symptomatic patients
Published	06/26/2023	characterization of pulmonary arterial hypertension (PAH)PAH is characterized by pathological changes in the pulmonary arteries: vasoconstriction, vas…
Published	06/26/2023	PAH results in both impaired {{c1::vasodilation}} and enhanced {{c1::vasoconstriction}}
Published	06/26/2023	pathophysiology of PH : RV failure syndrome
Published	06/26/2023	PAH clinical presentation MC → {{c1::dyspnea on exertion}}fatigue, chest pain physical findings → loud pulmonary component of {{c2…
Published	06/26/2023	PAH clinical presentation in stages
Published	06/26/2023	natural progression of PAH
Published	06/26/2023	physiiological assessments in PAH chest x-ray → abnormal findings → central pulmonary {{c1::arterial dilation}}, pruining of {{c1::peri…
Published	06/26/2023	an ECHO in PAH can cause → {{c1::tricuspid regurgitation}} and {{c1::TR jet velocity}}
Published	06/26/2023	PAH diagnosis → right heart cathertization required to establish and confirm PAH diagnosis PAH is defined by elevated mPAP >{{c1::20}}, P…
Published	06/26/2023	PAH diagnosis → other {{c1::diagnostic}} tests
Published	06/26/2023	most common drug to cause PAH → {{c1::methampetimines}}
Published	06/26/2023	PAH → treatment currently {{c1::no cure}}modern therapies can markedly improve pts symptoms and slow rate of clinical deteriation management…
Published	06/26/2023	PAH treatment goals Improvement in funcitonal class → target is {{c1::FC2}}improvement in exercise capacity → target is {{c1::6 MWD &gt…
Published	06/26/2023	PAH treatment → general and supportive measures general measures included {{c1::early referral to expert center}} and limit effects of exter…
Published	06/26/2023	PAH treatment → pharmacological targets
Published	06/26/2023	PAH therapy : prostacyclin pathway
Published	06/26/2023	PAH therapy → NO pathway
Published	06/26/2023	PAH therapy → endothelin pathway
Published	06/26/2023	summary of PAH early diagnosis is important First screening test is {{c1::echocardiogram}}consider early referral to expert center&nbsp…
Published	06/26/2023	even the earliest diagnosis will show a {{c1::tricuspid murmur}} and question how much it's leaking greater than 2.9 is likely confirmatory …
Published	06/26/2023	the locations of right heart catheterization internal {{c1::jugular}} vein{{c1::brachial}} vein {{c1::femoral}} vein
Published	06/26/2023	during right heart catheritization a test is done to see if the pt responds to {{c1::CCB's}}, usually amolodopine, but the pts that actually resp…
Status	Last Update	Fields