Notes in BIOC2600::L19 GPCRs (Signal Transduction II)

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Published 11/16/2024 what is the general structure of GPCRs? and what is it coupled with?
Published 11/16/2024 Describe the interaction and movement of heterotrimeric G-protein subunits (Gα, Gβ, Gγ) with the plasma membrane, focusing on their stability (e.g. ac…
Published 11/16/2024 [comprehensive] describe the 0th (inactive) to 4th steps of the general GPCR pathway [process mechanism]
Published 11/16/2024 in relation to G𝛂, GDP, and GTP, when is GPCR said to be active and inactive?
Published 11/16/2024 What are the three isoforms of Ga, and its general functions?sometimes be referred to as merely GX - which omits the Gα part of GαX (where X represent…
Published 11/16/2024 What is the role of G𝛂s (or Gs) in the GPCR pathway?
Published 11/16/2024 what is cAMP broken down into?
Published 11/16/2024 [comprehensive] what are 'second messengers'? also give two examples of enzymes that produce second messengers
Published 11/16/2024 Describe steps of the specific signaling pathway initiated by activated Gαs (stimulatory) proteins.Hint: enzyme is adenylyl (or adenylate) cyclase
Published 11/16/2024 Describe steps of the specific signaling pathway initiated by activated Gαi (inhibitory) proteins.(hint: bascially reverse of Gs)What kind of adrenerg…
Published 11/16/2024 Describe steps of the specific signaling pathway initiated by activated Gαq (quest for calcium) proteins.(hint: enzyme is PLC)
Published 11/16/2024 What kind of adrenergic receptors are linked to Gαi?
Published 11/16/2024 what kind of receptors (GPCRs) are Gαs coupled with?
Published 11/16/2024 what kind of receptors (GPCRs) are Gαq coupled with?
Published 11/16/2024 which Gα isoform is α2-adrenergic receptors linked with?
Published 11/16/2024 which Gα isoform is α1-adrenergic receptors linked with?
Published 11/16/2024 which Gα isoform are β-adrenergic receptors linked with?
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