Notes in Case 1: ANCA Associated Vasculitis

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Published	01/26/2024	{{c1::Ondansetron (Zofran)::drug}} {{c2::inhibits::activates/inhibits}} {{c3::serotonin receptors::target}}, which is useful in treating nausea
Published	01/26/2024	In ANCA associated small vessel vasculitides, anti-neutrophil cytoplasmic antibodies arise because antigens from {{c1::neutrophil granules}}…
Published	01/26/2024	In ANCA-associated small-vessel vasculitides, the positive feedback loop of recruiting more neutrophils and then reacting against them is mediated by&…
Published	01/26/2024	ANCA associated small vessel vasculitides may present with {{c1::palpable purpura::skin abnormality}}
Published	01/26/2024	ANCA associated small vessel vasculitides may present with {{c1::scleritis::eye abnormality}}
Published	01/26/2024	The general treatment for vasculitis is {{c1::steroids}} + {{c1::immunosuppressants}}
Published	01/26/2024	{{c2::Ondansetron}} antagonizes the {{c1::5-HT3}} receptor on vagal afferents in the GI tract
Published	01/26/2024	Polyarteritis nodosa is a form of {{c1::medium}}-vessel vasculitis
Published	01/26/2024	Polyarteritis nodosa is a necrotizing vasculitis that involves most organs, except the {{c1::lungs}}
Published	01/26/2024	Polyarteritis nodosa may present with {{c1::hypertension}} due to involvement of the renal artery
Published	01/26/2024	Polyarteritis nodosa may present with {{c1::abdominal}} pain and {{c1::melena}} due to involvement of the mesenteric artery
Published	01/26/2024	Polyarteritis nodosa may present with {{c1::polyneuropathy::neuro}} and/or {{c1::stroke::neuro}}
Published	01/26/2024	Polyarteritis nodosa may present with {{c1::skin}} lesions in up to 1/3 of patients
Published	01/26/2024	{{c2::Polyarteritis nodosa}} is a necrotizing vasculitis that is associated with positive serum {{c1::HBsAg}} in 30% of patients
Published	01/26/2024	The combination of dilatation (aneurysms) and narrowing (fibrosis) in polyarteritis nodosa gives blood vessels a(n) {{c1::"string of pearls"}} appeara…
Published	01/26/2024	Polyarteritis nodosa is characterized by innumerable renal {{c1::microaneurysms}} and spasms on arteriogram
Published	01/26/2024	What drugs may be used to treat a patient with polyarteritis nodosa? {{c1::Glucocorticoids, cyclophosphamide::2}}
Published	01/26/2024	Which artery is commonly affected in Kawasaki disease?{{c1::Coronary artery}}
Published	01/26/2024	The symptoms of {{c1::Kawasaki}} disease may be remembered with the mnemonic "CRASH and burn": {{c1::Conjunctivitis (bilateral)::C}}{{c1::Rash (polymo…
Published	01/26/2024	The symptoms of Kawasaki disease may be remembered with the mnemonic {{c1::CRASH and burn}}
Published	01/26/2024	Treatment for Kawasaki disease includes {{c1::aspirin}} and {{c1::IVIG}}
Published	01/26/2024	What significant laboratory finding is associated with granulomatosis with polyangiitis (GPA)?{{c1::Positive c-ANCA}}
Published	01/26/2024	What significant laboratory finding is associated with microscopic polyangiitis?{{c1::Positive p-ANCA}}
Published	01/26/2024	What significant laboratory finding is associated with eosinophilic granulomatosis with polyangiitis (EGPA)?{{c1::Positive p-ANCA}}
Published	01/26/2024	IgA vasculitis (Henoch-Schönlein purpura) is a form of {{c1::small}}-vessel vasculitis
Published	01/26/2024	IgA vasculitis (Henoch-Schönlein purpura) is a vasculitis that occurs secondary to {{c1::IgA immune complex}} deposition
Published	01/26/2024	The classic clinical triad of {{c2::IgA vasculitis (Henoch-Schönlein purpura)}} is:- {{c1::Palpable purpura}} on the buttocks and legs- {{c1::Arthralg…
Published	01/26/2024	IgA vasculitis (Henoch-Schönlein purpura) often occurs following a(n) {{c1::upper respiratory tract}} infection, which leads to generation of IgA
Published	01/26/2024	Which two vasculitides are associated with positive serum p-ANCA?{{c1::Eosinophilic granulomatosis with polyangiitis (EGPA) and microscopic polyangiit…
Published	01/26/2024	What type of hypersensitivity reaction occurs in polyarteritis nodosa? {{c1::Type III (immune-complex mediated)}}
Published	01/26/2024	Which cause of pauci-immune glomerulonephritis is associated with c-ANCA (PR3-ANCA)? {{c1::Granulomatosis with polyangiitis (GPA)}}
Published	01/26/2024	Which causes of pauci-immune glomerulonephritis are associated with p-ANCA (MPO-ANCA)? {{c1::Microscopic polyangiitis, eosinophilic granulomatosis wit…
Published	01/26/2024	What vasculitis is treated with aspirin? {{c1::Kawasaki disease}}
Published	01/26/2024	Polyarteritis nodosa associated with hepatitis B virus can affect the vessels of the {{c1::kidney}}, resulting in hypertension and decreased GFR
Published	01/26/2024	What vasculitis may present with palpable purpura, livedo reticularis and subcutaneous nodules?{{c1::Polyarteritis nodosa (seen in 33% of patients)}}
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