Notes in Histopathology Epithelium

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Published	08/28/2024	What fibrous protein make up intermediate filaments?{{c1::a-kerotin}}
Published	08/28/2024	What is transitional epithelium?Epithelium that can {{c1::change its shape}} based on the environment
Published	08/28/2024	What is pseudostratified epithelium?Looks like there's multiple layers because of {{c1::nuclei not being lined up}}, but all cells = {{c1::a…
Published	08/28/2024	What are the 3 types of apical specializations in epithelial cells?1) {{c1::Microvilli}}2) {{c1::Stereocilia}}3) {{c1::Cilia}}
Published	08/28/2024	What is the ∆ence btwn the two types of glandular epithelia?Endocrine glands: {{c1::secretle hormones to blood --> body}}Exocrine glands:&nbsp…
Published	08/28/2024	How can you classify multicellular exocrine epithelia?Its 1) {{c1::shape}}2) {{c1::# of ducts}}3) {{c1::secretion type}}4) {{…
Published	08/28/2024	Integrins bind to {{c1::ECM proteins}}
Published	08/28/2024	Cadherins and selectins are {{c1::Ca2+-DEPENDENT}}, while IgGs (immunoglobins) and Integrins are {{c1::Ca2+-INDEPENDENT}}
Published	08/28/2024	"Zonula" cell-cell adhesions form a {{c1::belt-like structure}}, while "macula" adhesions form {{c1::"spots"}}
Published	08/28/2024	Tight junctions zip membranes together with {{c1::Occludin}}, {{c1::claudin}}, and {{c1::JAM}}
Published	08/28/2024	Zonula Adherins use {{c1::E-cadherin}}, "zip" together
Published	08/28/2024	Hemisdesmosomes use {{c1::integrins}} to anchor {{c1::intemediate filaments}} to the ECM
Published	08/28/2024	Focal Adhesions use {{c1::integrins}} to connect {{c1::actin cytoskeleton}} to ECM
Published	08/28/2024	Microfilaments form from what monomer?{{c1::G-actin, linking up in a polar way}}{{c1::ATP-actin}} polimerizes, {{c1::ADP-Actin}} depolymerizes
Published	08/28/2024	Which is a better chemotherapeutic target? MTs or Microfilaments?{{c1::Microtubules}}
Published	08/28/2024	Which proteins act as motors along microfilaments?{{c1::Myosin}}
Published	08/28/2024	Why are Intermediate filaments diseases tissue-specific?{{c1::∆ famillies of IFs are localized to ∆ tissues}}
Published	08/28/2024	How can you distinguish between squamous keratinized epithelium and squamous epithelium?Keratin = strands on the {{c1::top of the squamous epithe…
Published	08/28/2024	What type of junction restricts lipid / protein movement both between cells, and from the apical -->basolater membranes?{{c1::Tight Junction}}
Published	08/28/2024	Stratified Squamous Epithelia can look keratinzied! How can you tell if it isnt?{{c1::Top layer cells still have their nuclei}}
Published	08/28/2024	Three important descriptors of epithelial cells are that they are {{c1::polarized}}, {{c2::avascular}}, and {{c3::form a selective barrier at surfaces…
Published	08/28/2024	The structure shown here is {{c1::microvilli}}
Published	08/28/2024	The structures shown here on the apical layer are {{c1::cilia}}
Published	08/28/2024	The structure shown on the apical layer are {{c1::stereocilia}}
Published	08/28/2024	What is the main difference between merocrine, apocrine, and holocrine glands?Merocrine secrete {{c1::fluid}}Apocrine secrete {{c1::part of their glan…
Published	08/28/2024	The three types of cell-cell junctions are {{c1::zona occludens (tight jxns), zonula adherins, and macula adherins (desmosomes)}}
Published	08/28/2024	The two types of cell-matrix junctions are {{c1::hemidesmosomes and focal adhesions}}
Published	08/28/2024	Why are plant alkaloids used as chemotherapuetic drugs?{{c1::Because they bind all beta-tubulin which stop the mitotic spindle and cell growth from co…
Published	08/28/2024	Examples of plant alkaloids that are used for chemotherapeutic agents are {{c1::colchicine, vinblastine, and taxol}}
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