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Published	07/22/2024	Baltimore classficiation of viruses: name the three major clases
Published	07/22/2024	Baltimore classficiation of viruses: two types of DNA viruses
Published	07/22/2024	Baltimore classficiation of viruses: types of RNA viruses
Published	07/22/2024	what's the difference between +ssRNA and -ssRNA viruses?
Published	07/22/2024	Baltimore classficiation of viruses: types of retro-transcribing viruses
Published	07/22/2024	What are the two major therapeutic ways of fighting a virus?
Published	07/22/2024	is there a prophylatic vaccine for: rubella
Published	07/22/2024	is there a prophylatic vaccine for: varicella
Published	07/22/2024	is there a prophylatic vaccine for: cholera
Published	07/22/2024	is there a prophylatic vaccine for: diphteria
Published	07/22/2024	is there a prophylatic vaccine for: tetanus
Published	07/22/2024	is there a prophylatic vaccine for: typhus
Published	07/22/2024	is there a prophylatic vaccine for: pneumococci
Published	07/22/2024	antiviral drugs: first potential target
Published	07/22/2024	antiviral drugs: last potential target
Published	07/22/2024	antiviral drugs: anti-replication
Published	07/22/2024	antiviral drugs: translation
Published	07/22/2024	How do viruses escape the innate immune system
Published	07/22/2024	How do viruses escape the adaptive immune system
Published	07/22/2024	Name the three HUMAN corona viruses
Published	07/22/2024	what part of the human body do coronaviruses usually infect
Published	07/22/2024	What kind of a virus is the coronavirus
Published	07/22/2024	the corona virus' genome encodes which STRUCTURAL proteins:
Published	07/22/2024	which coronavirus proteins are highly immunogenic
Published	07/22/2024	name the two subunits of the coronavirus' spike protein
Published	07/22/2024	typical disease course (coronavirus)
Published	07/22/2024	duration of mild-case coronavirus infection
Published	07/22/2024	duration of severe-case coronavirus infection
Published	07/22/2024	stages of coronavirus infection
Published	07/22/2024	cytokines and chemokines that lead to systemic accute inflammation COVID
Published	07/22/2024	why does the humoral immune system not aid against COVID (upon first infection)
Published	07/22/2024	COVID and the innate immune system: TLRs
Published	07/22/2024	COVID and the innate immune system: RIG
Published	07/22/2024	How does coronavirus interefere with type I IFN
Published	07/22/2024	a virus' three effects on cells
Published	07/22/2024	What for do viruses need RAF/MEK/ERK?
Published	07/22/2024	Which two effects does MEK inhibition have in the context of viral infection?
Published	07/22/2024	What kind of antiviral activity does MEK inhibition have?
Published	07/22/2024	What kind of immunomodulatory effects does MEK inhibition have?
Published	07/22/2024	Mechanical signals ... cell polarity and cell adhesion
Published	07/22/2024	in tangential force the force is ... to the are
Published	07/22/2024	In what way are tensile force and compression force related
Published	07/22/2024	name three extrinsic forces
Published	07/22/2024	name three intrinsic forces
Published	07/22/2024	what is the difference between mechanosensing and mechanotransduction
Published	07/22/2024	Name two types of models of mechanosensitive ion channels
Published	07/22/2024	Give an example of a single tethe mechanosensitive ion channel
Published	07/22/2024	Give an example of a membrane-force mechanosensitive ion channel
Published	07/22/2024	How do applied forces modify the reactivity of mechanosensitive molecules?
Published	07/22/2024	what are catch bonds
Published	07/22/2024	what are slip bonds
Published	07/22/2024	Name the four models of how catch bonds work
Published	07/22/2024	what is the time scales on which mechanical signalling affects cells
Published	07/22/2024	are drosophila muscles under increasing tention during development
Published	07/22/2024	how does FRET work?
Published	07/22/2024	How tention on talin molecules develop throughout the development of drosophila?
Published	07/22/2024	name the three ways that cellular structures may be reinforced to distribute force under stress
Published	07/22/2024	Which three mechanisms may be used by cells exposed to persitent mechanical stress?
Published	07/22/2024	How does shear stress impact on cellular metabolism
Published	07/22/2024	What is the LINC complex?
Published	07/22/2024	How do changes in cell tension influence gene expression?
Published	07/22/2024	What is Hippo?
Published	07/22/2024	Hippo is important in which types of animals (at least)?
Published	07/22/2024	What is YAP?
Published	07/22/2024	How is YAP regulated?
Published	07/22/2024	What does YAP do in the nucleus?
Published	07/22/2024	What kind of cellular states/processes are promoted by YAP?
Published	07/22/2024	How do mechanical cues impact on the Hippo pathway?
Published	07/22/2024	What is TAZ?
Published	07/22/2024	Which of the following components is not part of the mechanical link mediated by integrin adhesion complexes at the plasma membrane?
Published	07/22/2024	Which proteins are part of the LINC complex?
Published	07/22/2024	Are all tumors life threatening?
Published	07/22/2024	What is the difference between a benign and a malignant tumor?
Published	07/22/2024	Which two high level alterations in cellular processes lead to tumor formation?
Published	07/22/2024	Which percentage of tumor cells that enter the bloodstream end up forming metasteses?
Published	07/22/2024	Name three DNA virus families that cause cancer
Published	07/22/2024	Name two families of RNA viruses that cause cancer
Published	07/22/2024	How can viral infection cause cancer?
Published	07/22/2024	What event in viral infection makes tumor appearance more likely?
Published	07/22/2024	What is imatinib?
Published	07/22/2024	What is the Bcr (-B cells)?
Published	07/22/2024	How do the Bcr and Abl often interact in the context of cancer?
Published	07/22/2024	What does Abl do?
Published	07/22/2024	In how far is the order of acquisition of mutations in the process of cancerogenesis important?
Published	07/22/2024	Why is combinatory treatment important in cancer therapy?
Published	07/22/2024	What structure is responsible for processing MHCI peptides?
Published	07/23/2024	Which group of proteins processes MHCII peptides?
Published	07/22/2024	What does the X stand for in HLA-X?
Published	07/22/2024	What is the HLA?
Published	07/22/2024	MHCI binds to which receptor?
Published	07/23/2024	MHCII binds to which co-receptor?
Published	07/22/2024	Which region of the MHC molecule accounts for the majority of inter-MHC difference?
Published	07/23/2024	Where do the peptide fragments (generally) come from that are presented by MHCII?
Published	07/22/2024	Where do the peptides come from that are presented by MHCI?
Published	07/22/2024	What is cross-presentation?
Published	07/22/2024	What are two emerging hallmarks of cancer?
Published	07/22/2024	What are two important enabling characteristics of cancer
Published	07/22/2024	What is checkpoint inhibitor therapy?
Published	07/22/2024	What is one complication of checkpoint inhibitor therapy?
Published	07/22/2024	How are algae grouped/defined?
Published	07/22/2024	How is the breadth of phylogenetic distribution of algae explained?
Published	07/22/2024	Which four things are key characteristics of multicellularity?
Published	07/22/2024	Name two strategies for cell-cell communication employed by different algae
Published	07/22/2024	The last common ancestor of plants, animals, and brown algae was
Published	07/22/2024	Which two sex chromosomes do brown algae have?
Published	07/22/2024	The V chromosome in brown algae is the male/female one?
Published	07/22/2024	The U chromosome in brown algae is the male/female one?
Published	07/22/2024	The brown algae life cycle is
Published	07/22/2024	What is HMG-domain TF?
Published	07/22/2024	What is the role of HMG-domain TF in brown algae?
Published	07/22/2024	Beyond brown algae, what is the hypothesised function of HMG genes/proteins?
Published	07/22/2024	Are all algae multicellular?
Published	07/22/2024	Brown algae are NOT used to study which of these things
Published	07/22/2024	what aspects of culturing make Ectocarpus a good model organism
Published	07/22/2024	what aspects of genomics make Ectocarpus a good model organism
Published	07/22/2024	Characteristics of stem cells
Published	07/22/2024	How is stem cell behaviour regulated?
Published	07/22/2024	Five steps of an evolutionary model of the emergence of sex chromosomes
Published	07/22/2024	What are stem cell niches?
Published	07/22/2024	Definition: Totipotent
Published	07/22/2024	Definition: Pluripotent
Published	07/22/2024	Definition: Multipotent
Published	07/22/2024	Definition: Unipotent
Published	07/22/2024	Which transcription factors are sufficient to establish pluripotency?
Published	07/22/2024	Which two transcription factors are part of the original Yamanaka factors for reprogramming as well as of the core regulatory circuit for the maintena…
Published	07/22/2024	How long does it take to generate ES cell-derivded transgenic mice?
Published	07/22/2024	Where are stem cells that renew the epithelium of the gut found?
Published	07/24/2024	What is the major concern of using retroviral vectors to deliver transcription factors for reprogramming somatic cells towards pluripotency?
Published	07/22/2024	From which tissue are embryonic stem cells derived from?
Published	07/22/2024	Definition: Transdifferentiation
Published	07/22/2024	The first nuclear transplant from a somatic animal cell to an egg that produced a normal adult was performed on a... ?
Published	07/22/2024	Example: Totipotent cells
Published	07/22/2024	What does the "Waddington's hill" metaphor represent?
Published	07/22/2024	Phases of reprogramming
Published	07/22/2024	name 5 criteria to assess the development potential of pluripotent stem cells
Published	07/22/2024	Categories of tumor peptides/antigens
Published	07/22/2024	Which test for naive pluripotency is the most stringent one?
Published	07/22/2024	What happens during the stochastic phase of stem cell reprogramming?
Published	07/22/2024	What happens during the deterministic phase of stem cell reprogramming?
Published	07/22/2024	Stem cell therapy is based on which type of stem cells?
Published	07/22/2024	What does Autophagy mean to you?
Published	07/22/2024	What cell organells are these?
Published	07/22/2024	What kind of autophagy is shown here?
Published	07/22/2024	What protein is the ULK1 complex made out of?
Published	07/22/2024	What proteins is the PI3KC3 complex I made of?
Published	07/22/2024	What does the ULK1 complex phosphorylate?
Published	07/22/2024	Which complexes are resposible for Phagophor nucleation?
Published	07/22/2024	What lipids are omegasomes (pre-phagophor) made of?
Published	07/22/2024	What are the membrane sources for autophagosomes?
Published	07/22/2024	What protein does the vesicles that 'feed' the autophagosome contain?
Published	07/22/2024	Which 2 proteins bind to the newly forming omegasome?
Published	07/22/2024	Which protein binds to WIPI2 during cargo sequestration(and which proteins bind to it)
Published	07/22/2024	Which protein makes LC3 go from cytosolic to membrane-bound?
Published	07/22/2024	What receptors are used to select autophagosome cargo?
Published	07/22/2024	What is special about the autophagosome mebrane?
Published	07/22/2024	With which cell organelle does the autophagosome fuse?
Published	07/22/2024	Does autophagy protect from disease?
Published	07/22/2024	How does autophagy prevent cancer?
Published	07/22/2024	How does autophagy promote cancer?
Published	07/22/2024	What kind of gene is TP53?
Published	07/22/2024	What is p53?
Published	07/22/2024	What protein regulates p53?
Published	07/22/2024	What is the function of p53?
Published	07/22/2024	How is p53 and autophagy connected?
Published	07/22/2024	What kind of disease is triggered by mutations in the WIPI genes?
Published	07/22/2024	Which protein makes double strand breaks during Meiosis 1?
Published	07/22/2024	What kind of protein is Spo 11?
Published	07/22/2024	How are double strand breaks regulated during Meiosis1?
Published	07/22/2024	How many subunits does the Spo11 complex have?(in yeast)
Published	07/22/2024	What proteins is the Spo11 complex made out of? And what are their functions?(in yeast)
Published	07/22/2024	How many Spo11 complexes are needed to break dsDNA?
Published	07/22/2024	What is special about purified Spo11?
Published	07/22/2024	What are the three kinds of autophagy?
Published	07/22/2024	What is microautophagy?
Published	07/22/2024	Why cant you just KO autophagy to study it (in vertebrae)?
Published	07/22/2024	What influence do extra-cellular physical cues have on cells?
Published	07/22/2024	Why do researchers make devices that expose cells to physical cues?
Published	07/22/2024	Name the seven methods that were mentioned as techniques to measure cell (&bacteria) biomechanics
Published	07/22/2024	What does atomic force microscopy measure?
Published	07/22/2024	What are the 2 mentioned model organsims for intracellular bacteria?
Published	07/22/2024	What kind of pathogen is Listeria monocytogenes?What symptoms does it entail?
Published	07/22/2024	What kind of pathogen is Ricksettia parkeri?what are the sympoms?
Published	07/22/2024	What part of the cytoskeleton allows intracellular bacteria to spread from cell to cell?
Published	07/22/2024	How does Rickettsia overcome the tension faced at the membrane to create a protrusion?
Published	07/22/2024	Do (unrelated) bacterial species that use actin-based motility, use the same mechanisms?
Published	07/22/2024	What is a physical way how host cells get rid of infected cells?
Published	07/22/2024	How does Listeria infection influence the movement of host cells?
Published	07/22/2024	Is there an infection mound when 100% of cells are infected?
Published	07/22/2024	What could be observed during late infection?
Published	07/22/2024	Is brain tissue elastic or viscoelastic?
Published	07/22/2024	Whats the difference and similarities between elastic and viscoelastic?
Published	07/22/2024	Whats the problem with using Hydrogel as a model for tissues (f.e. brain)?
Published	07/22/2024	How is contractility and traction in infected cells affected?
Published	07/22/2024	How does the 'texture' of cells change when infected?
Published	07/22/2024	Is there a differnce between 'normal' 'healthy' cells and 'surrounders' of an infection mound?
Published	07/22/2024	How can (infection) mounding be inhibited?
Published	07/22/2024	(Accordins to in silico prediction) what is suffiecient to drive mounding?
Published	07/22/2024	Are there transcriptional changes between infected mounders and uninfected surrounders?
Published	07/22/2024	Inibition of which signaling attenuates mounding?
Published	07/22/2024	Inhibition of which process does not attenuate mounding?
Status	Last Update	Fields