Notes in Hepatitis and Chronic Liver Disease

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Status	Last Update	Fields
Published	03/03/2024	All blood leaves liver via {{c1::hepatic veins}} and converges into the {{c1::inferior vena cava}}
Published	03/03/2024	Deoxygenated blood from {{c2::stomach, spleen, pancreas, small intestine, and colon}} travels to the liver via {{c1::hepatic portal vein}}
Published	03/03/2024	Oxygenated blood from {{c1::aorta}} travels to the liver via the {{c1::hepatic artery}}
Published	03/03/2024	Portal and arterial blood flows from {{c1::portal triad}} towards {{c1::central vein }}
Published	03/03/2024	Bile flow flows away from {{c1::central vein}} to the {{c1::portal triad and bile duct}}
Published	03/03/2024	{{c1::Cholangiocytes}} are the cells that make up the bile duct
Published	03/03/2024	What protein synthesis occurs in the liver (general)?
Published	03/03/2024	{{c1::VLDL}} transports {{c2::triglycerides, fatty acids and cholesterol}}
Published	03/03/2024	{{c1::HDL}} transports {{c2::cholestero}}l back to liver and used for {{c3::gluconeogenesis and bile salt production}}
Published	03/03/2024	How does amino acid deamination work?
Published	03/03/2024	How does Amino acid transamination work?
Published	03/03/2024	What is bile?
Published	03/03/2024	What is the function of bile?
Published	03/03/2024	How does the liver peform detoxification?
Published	03/03/2024	What are some common etiologies of cirrhosis?
Published	03/03/2024	A {{c1::nodular liver, splenomegaly, and portal collateral veins}} on imaging can indicate the presence of cirrhosis
Published	03/03/2024	What are some methods of diagnosing cirrhosis?
Published	03/03/2024	What are the cardinal signs of liver failure?
Published	03/03/2024	{{c1::Jaundice}} is a direct consequence of {{c2::synthetic failure}} of the liver
Published	03/03/2024	{{c2::Ascites and variceal bleed}} are two common complications of {{c1::portal hypertension}}
Published	03/03/2024	A combination of {{c1::portal hypertension and synthetic failure}} presents as {{c2::hepatic encephalopathy}} due to an increase in {{c3::ammonia leve…
Published	03/03/2024	{{c2::12mmHg}} is the value of {{c1::Hepatic Venous Pressure Gradient}} that is concerning for complications from portal hypertension
Published	03/03/2024	{{c1::Non-selective beta-blockers}} reduce {{c2::splanchnic blood flow}} and can be used as {{c3::prophylaxis for portal hypertension}}
Published	03/03/2024	A Neutrophil (PMN) count {{c2::> 250}} in peritoneal fluid is suggestive of {{c1::spontaneous bacterial peritonitis }}
Published	03/03/2024	{{c1::Furosemide and aldosterone antagonists}} are an effective treatment for ascites
Published	03/03/2024	What is the pathophysiology of ascites and hepatorenal syndrome?
Published	03/03/2024	What are common methods of managing HRS?
Published	03/03/2024	{{c1::Asterixis}} is a notable PE findings that can suggest {{c2::HE}}
Published	03/03/2024	{{c1::Rifaximin}} is a poorly absorbed antibiotic that is thought to {{c2::reduce ammonia}} production by {{c3::eliminating ammonia-producin…
Published	03/03/2024	MELD {{c1::> 15}} generally criteria for {{c2::liver transplant evaluation}}
Published	03/03/2024	{{c3::Serum ascites albumin gradient (SAAG)}}, which is {{c1::based on the difference between the albumin level of serum and of ascitic fluid,}} …
Published	03/03/2024	What are the factors in the CTP score?
Published	03/03/2024	What are the factors in the MELD score?
Published	03/03/2024	How does HCC present on MRI?
Published	03/03/2024	{{c1::ALT::lab test}} most specific to the hepatocyte.
Published	03/03/2024	{{c1::GGT}} can help determine if liver function test elevation is from liver vs non-liver source
Published	03/03/2024	{{c1::Hepatocellular injury (damage to hepatocytes)}} is defined as disproportionate elevation of {{c2::AST/ALT levels}} as compared to the {{c2::ALP …
Published	03/03/2024	{{c1::Cholestatic injury (impaired bile secretion and flow)}} is defined as disproportionate elevation in {{c2::ALP level}} as compared to {{c2::AST/A…
Published	03/03/2024	{{c1::Degree of elevation}} of AST/ALT can help differentiate between acute versus chronic
Published	03/04/2024	What is the mode of transmission for Hep A?
Published	03/04/2024	{{c2::Outer surface membrane}} contains {{c3::hepatitis B surface antigen (HBsAg)}} which is indicative of {{c1::active infection}}
Published	03/04/2024	What are the risk factors for Hep B infection?
Published	03/04/2024	What is the current treatment for Hepatitis C?
Published	03/04/2024	HDV requires {{c1::HBV}} for {{c2::assembly and infection (HBV surface antigen)}}
Published	03/04/2024	How is Hepatitis E transmitted?
Published	03/04/2024	{{c1::Hepatitis E}} has up to 20% mortality among {{c2::pregnant women}}
Published	03/04/2024	Definition of Alcohol-associated Hepatitis (AAH)?
Published	03/04/2024	Why is AST more prevalent in AAH?
Status	Last Update	Fields