Notes in Tryps - S. American & African

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Status	Last Update	Fields
Published	01/10/2024	T. brucei gambiense: {{c1::>98}}% of sleeping sickness cases{{c1::West and Central Africa, Uganda::geography}}{{c1::Gradual}} onset{{c1::…
Published	01/10/2024	T. brucei rhodesiense: {{c1::<2}}% of sleeping sickness cases{{c1::East and South Africa, Uganda::geography}}{{c1::Rapid}} onsetRese…
Published	01/10/2024	Transmission of T. brucei = {{c1::tsetse fly}}Painful biteFound in {{c1::rural woodlands, forests, warm/shaded areas::3}}Lifespan = {{c1::1-…
Published	01/10/2024	Epidemiology of T. brucei30 sub saharan countriesMost cases in {{c1::Democratic Republic of Congo}} (>70% of cases), South Sudan, Central African R…
Published	01/10/2024	Epidemiology of American trypanosomiasis/Chagas diseaseEndemic in 21 countries: {{c1::South America, Central America, US}}100 million people…
Published	01/10/2024	T. cruzi{{c1::Flagellate}}: in peripheral blood, biological fluids{{c1::Non-flagellate/amastigote}}: in tissues of infected animals, humans{{c1::Intra…
Published	01/10/2024	Transmission of American trypanosomiasis/Chagas disease{{c1::Vertical}}{{c1::Sexually}}{{c1::Oral - Shared food}}Accidental in {{c1::la…
Published	01/10/2024	T. cruzi vector = {{c1::Reduviid “kissing” bug}}Transmitted through {{c1::direct bite}} or through {{c1::mucosal surface}}{{c1::Falling…
Published	01/10/2024	Clinical presentation of Human african trypanosomiasis (HAT){{c1::Chancre}} More in rhodiense, rare in gambienseIndurated, may ulcerateTenderOnse…
Published	01/10/2024	Complications in Human african trypanosomiasis (HAT){{c1::Myocarditis, effusions}}{{c1::Hypothyroidism, hypoadrenalism}}{{c1::behavioral/psychiat…
Published	01/10/2024	Clinical staging of Human african trypanosomiasis (HAT)Stage 1:{{c1::early, no invasion of CNS, hemolymphatic stage}}Stage 2: {{c1::late, invasio…
Published	01/10/2024	Diagnosis of Human african trypanosomiasis (HAT)Demonstration of {{c1::parasite}}{{c1::Blood film}}Easier in rhodienseBlood concentration techniq…
Published	01/10/2024	Differential diagnoses for Human african trypanosomiasis (HAT){{c1::HIV}}{{c1::TB}}{{c1::Toxoplasmosis in HIV (CD4<100)}}{{c1::Meningitis}}{{c1::Ly…
Published	01/10/2024	American trypanosomiasis/Chagas disease clinical featuresMajority {{c1::asymptomatic}} - important to screen!Acute Chagas infection{{c2::Romana’s…
Published	01/10/2024	American trypanosomiasis/Chagas disease diagnosisPeripheral blood: {{c1::trypomastigotes}} in blood film{{c1::Xenodiagnosis}}{{c1::Amastigotes}}&…
Published	01/10/2024	American trypanosomiasis/Chagas disease treatment indications{{c1::Cure}} in acute phase{{c1::Pre-transplant}}{{c1::Reactivation}} in immuno…
Published	01/10/2024	American trypanosomiasis/Chagas disease treatment Treat for at least {{c1::60}} days{{c1::Benznidazole}}Side effects: dermatological, photos…
Published	01/10/2024	Human african trypanosomiasis (HAT) preventionVector control: {{c1::aerial insecticide spraying, fly trap, insecticide-impregnated screens, reduc…
Published	01/10/2024	American trypanosomiasis/Chagas disease preventionVector control:{{c1::insecticides, mosquito nets}}Change {{c1::structure}} of homesCover {{c1::…
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