Notes in Rectal cancer

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Status	Last Update	Fields
Published	02/18/2024	GI \| Rectal \| 3.1 \| Workup
Published	02/18/2024	GI \| Rectal \| 2.6 \| Clinical Presentation
Published	02/18/2024	GI \| Rectal \| 2.7.1 \| Staging - T classification (AJCC 8th edition 2017)
Published	02/18/2024	GI \| Rectal \| 2.7.2 \| Staging - N classification (AJCC 8th edition 2017)
Published	02/18/2024	GI \| Rectal \| 2.7.3 \| Staging - M classification (AJCC 8th edition 2017)
Published	02/18/2024	GI \| Rectal \| 2.7.4 \| Staging - Overall Stage (AJCC 8th edition 2017)
Published	02/18/2024	GI \| Rectal \| 5.1 \| Stage I \| Management
Published	02/18/2024	GI \| Rectal \| 6.1 \| Stage II-III \| Management \| Stage II (T3-4N0M0) or Stage III (any N+)
Published	02/18/2024	GI \| Rectal \| 5.2 \| Stage I \| Adjuvant chemoradiotherapy \| Indications for adjuvant chemoradiotherapy (either clinical stage I or stage II-III not tre…
Published	02/18/2024	GI \| Rectal \| 6.5 \| Stage II-III \| Follow up (NCCN guidelines)
Published	02/18/2024	GI \| Rectal \| 6.3.2 \| Stage II-III \| Evidence for neoadjuvant RT \| SCRT vs. upfront surgery \| "Dutch TME Trial" van Gjin et al NEJM 2001 345: 638 and …
Published	02/18/2024	GI \| Rectal \| 6.3.3 \| Stage II-III \| Evidence for neoadjuvant RT \| Pre-op CRT vs. postop CRT \| "German Trial" Sauer et al. NEJM 2004; 351:1731 an…
Published	02/18/2024	GI \| Rectal \| 6.3.6 \| Stage II-III \| Short course vs. long course RT alone \| "Stockholm Trial III" Erlandson et al. 2017 Lancet Oncol 18 (3):336-46
Published	02/18/2024	GI \| Rectal \| 6.3.4 \| Stage II-III \| Short course vs. long course \| TROG 01.04 Ngan 2012 J Clin Oncol 30(31):3827-3833
Published	02/18/2024	GI \| Rectal \| 6.3.9.1.2 \| Stage II-III \| Watch and wait \| Systematic review Dattani et al 2018 Ann Surg 268(6): 955-967
Published	02/18/2024	GI \| Rectal \| 6.4.2 \| Stage II-III \| RT Technique: Long course concurrent chemoradiotherapy
Published	02/18/2024	GI \| Rectal \| 6.4.4 \| Stage II-III \| Technique: Short course RT
Published	02/18/2024	GI \| Rectal \| 6.4.3 \| Stage II-III \| RT planning: OAR constraints for rectal cancer long course chemoRT (50Gy/25#)
Published	02/18/2024	GI \| Rectal \| 6.3.1 \| Stage II-III \| Landmark neoadjuvant trials \| List the key trials/studies in RT for rectal cancer + a one sentence summary of the…
Published	02/18/2024	GI \| Rectal \| 1.1 \| Anatomy
Published	02/18/2024	GI \| Rectal \| 1.2 \| Anatomy of mesorectum
Published	02/18/2024	GI \| Rectal \| 2.1 \| Epidemiology
Published	02/18/2024	GI \| Rectal \| 2.2 \| Aetiology and risk factors
Published	02/18/2024	GI \| Rectal \| 2.3.1 \| Lynch syndrome / HNPCC \| Epidemiology, genetics, clinical features, diagnosis and management
Published	02/18/2024	GI \| Rectal \| 2.4.1 \| Histopathologic classification
Published	02/18/2024	GI \| Rectal \| 2.4.2 \| Macroscopic and microscopic appearance
Published	02/18/2024	GI \| Rectal \| 2.5 \| Histopathology report \| List key factors to be included in the histopathology report for a colorectal specimen
Published	02/18/2024	GI \| Rectal \| 2.7 \| Biologic behaviour
Published	02/18/2024	GI \| Rectal \| 2.7.5 \| Historical staging systems \| Dukes classification and Modified Astler Coller classification
Published	02/18/2024	GI \| Rectal \| 2.4.3 \| Grading
Published	02/18/2024	GI \| Rectal \| 2.8 \| Prognostic factors
Published	02/18/2024	GI \| Rectal \| 3.2 \| DDx \| Provide a differential diagnosis for a colorectal mass
Published	02/18/2024	GI \| Rectal \| 4.1 \| Management \| Overview \| Provide an overview of the management of rectal adenocarcinoma
Published	02/18/2024	GI \| Rectal \| 4.2.1 \| Principles of Surgery \| Overview \| Give a brief overview of the principles of surgery for rectal cancer including:- Types of exc…
Published	02/18/2024	GI \| Rectal \| 4.2.2 \| Principles of Surgery \| Local excision \| Briefly describe the indications for, techniques, outcomes and further treatment requri…
Published	02/18/2024	GI \| Rectal \| 4.2.3 \| Principles of Surgery \| Low anterior resection (sphincter-sparing resection) \| Briefly describe the principles of low anterior r…
Published	02/18/2024	GI \| Rectal \| 4.2.4 \| Principles of Surgery \| Abdominal perineal resection \| Briefly describe the principles of abdominal perineal resection for recta…
Published	02/18/2024	GI \| Rectal \| 4.2.5 \| Principles of Surgery \| Multivisceral resection (exenteration) \| Briefly describe the principles of multivisceral resection for …
Published	02/18/2024	GI \| Rectal \| 4.2.6\| Principles of Surgery \| Surgical palliation
Published	02/18/2024	GI \| Rectal \| 6.2.1\| Stage II-III \| Neoadjuvant therapy \| Indications \| Discuss patient selection for neoadjuvant therapy in rectal cancer
Published	02/18/2024	GI \| Rectal \| 6.2.2.1 \| Stage II-III \| Neoadjuvant treatment strategies: SCRT vs. Long course CRT vs. TNT
Published	02/18/2024	GI \| Rectal \| 6.3.7.2 \| Stage II-III \| Long course chemoradiotherapy \| Choice of concurrent chemotherapy \| Capecitabine vs. 5FU (vs. addition of oxali…
Published	02/18/2024	GI \| Rectal \| 6.3.5 \| Stage II-III \| Short course vs. long course \| "Polish II trial" Annals of Oncology 27: 834–842, 2016
Published	02/18/2024	GI \| Rectal \| 6.2.2.2 \| Stage II-III \| Neoadjuvant treatment strategies \| Create a table to compare Long course chemoradiothearpy (LC CRT), short cour…
Published	02/18/2024	GI \| Rectal \| 6.3.7.1 \| Stage II-III \| Long course chemoradiotherapy \| Role of concurrent chemotherapy (and of adjuvant chemotherapy) \| EORTC 22921
Published	02/18/2024	GI \| Rectal \| 6.4.5 \| Stage II-III \| Late effects of RT
Published	02/18/2024	GI \| Rectal \| 6.4.1 \| Stage II-III \| RT technique \| IMRT vs. 3DCRT \| Discuss the role of IMRT vs. 3DCRT for rectal cancer
Published	02/18/2024	GI \| Rectal \| 6.3.8.3.4 \| Stage II-III \| Total neoadjuvant therapy \| Phase II RCT Garcia-Aguilar et al. Lancet Oncol. 2015 August ; 16(8): 957–966
Published	02/18/2024	GI \| Rectal \| 6.3.9.2 \| Stage II-III \| Omission of RT \| FOWARC trial (and PROSPECT)
Published	02/18/2024	GI \| Rectal \| 6.3.8.1 \| Stage II-III \| Adjuvant chemotherapy \| Briefly discuss the role of adjuvant chemotherapy in patients who have received neoadju…
Published	02/18/2024	GI \| Rectal \| 7.1 \| Stage IV \| Management \| Overview
Published	02/18/2024	GI \| Rectal \| 7.2.1 \| Stage IV \| Potentially resectable metastases \| Discuss the prognosis and briefly discuss the local management of isolated metast…
Published	02/18/2024	GI \| Rectal \| 7.2.2 \| Stage IV \| Potentially resectable metastases \| Management of the primary
Published	02/18/2024	GI \| Rectal \| 7.3.2 \| Stage IV \| Unresectable metastases \| Symptomatic primary \| Management of the primary \| Discuss the role of palliative radiothera…
Published	02/18/2024	GI \| Rectal \| 7.3.1 \| Stage IV \| Unresectable metastases \| Symptomatic primary \| Briefly discuss the local treatment options for management of a sympt…
Published	02/18/2024	GI \| Rectal \| 7.3.3 \| Stage IV \| Chemotherapy \| Briefly discuss first line chemotherapy for stage IV colorectal cancer
Published	02/18/2024	GI \| Rectal \| 8.1 \| Locoregional recurrence \| Management overview \| Provide an overview of the management of locally-recurrent rectal adenocarcinoma
Published	02/18/2024	GI \| Rectal \| 8.2 \| Locoregional recurrence \| Clinical presentation and workup
Published	02/18/2024	GI \| Rectal \| 9.1 \| Metastatic recurrence \| Briefly discuss the management of recurrent rectal cancer with metastatic disease
Published	02/18/2024	GI \| Rectal \| 8.3 \| Locoregional recurrence \| Surgical principles \| Briefly describe the principles of surgery for locally-recurrent rectal cancer
Published	02/18/2024	GI \| Rectal \| 8.4 \| Locoregional recurence \| Combined modality therapy \| Discuss the principles of combined modality therapy for locally-recurrent rec…
Published	02/18/2024	GI \| Rectal \| 6.3.9.1.1 \| Watch and wait
Published	02/18/2024	GI \| Rectal \| 3.1.2 \| Assessment of nodes on MRI
Published	02/18/2024	GI \| Rectal \| 8.5 \| Locoregional recurrence \| Re-irradiation \| Briefly discuss re-irradiation for locally recurrent rectal cancer
Published	02/18/2024	GI \| Rectal \| 2.2.2 \| Colorectal carcinogenesis
Published	02/18/2024	GI \| Rectal \| 6.3.8.3.2 \| Stage II-III \| Total neoadjuvant therapy \| RAPIDO trial vander Valk JCO 2020
Published	02/18/2024	GI \| Rectal \| 6.3.8.3.3 \| Stage II-III \| Total neoadjuvant therapy \| PRODIGE-23
Published	02/18/2024	GI \| Rectal \| 6.3.8.3.1 \| Stage II-III \| Neoadjuvant therapy \| Total neoadjuvant therapy (TNT)
Published	02/18/2024	GI \| Rectal \| 2.3.3 \| Peutz-Jeghers syndrome
Published	02/18/2024	GI \| Rectal \| TNT \| 6.2.2.1 \| OPRA trial
Status	Last Update	Fields