Notes in Allergy

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Status	Last Update	Fields
Published	10/08/2024	Type {{c3::I}} hypersensitivity reactions occur due to pre-formed Ig{{c1::E}} antibodies binding to {{c2::mast cells}} and {{c2::basophils}} (cell typ…
Published	10/08/2024	Type {{c1::II}} hypersensitivity reactions occur when antibodies attack our own tissues
Published	10/08/2024	Autoimmune hemolytic anemia is a type {{c1::II}} hypersensitivity reaction
Published	10/08/2024	Goodpasture syndrome involves autoantibodies against type {{c1::IV}} collagen
Published	10/08/2024	Type {{c1::III}} hypersensitivity reactions involves the formation of immune complexes
Published	10/08/2024	What are two prototypical examples of type III hypersensitivity reactions?
Published	10/08/2024	Type {{c1::IV}} hypersensitivity reactions do not involve antibodies
Published	10/08/2024	The PPD test involves a Type {{c1::IV}} hypersensitivity reaction
Published	10/08/2024	A positive PPD test will stimulate a Th{{c1::1}} response
Published	10/08/2024	Patients with {{c2::Selective IgA deficiency::immunodeficiency?}} are at an increased risk of {{c1::anaphylaxis}} with blood transfusions
Published	10/08/2024	Type I hypersensitivity reactions are driven by Th{{c1::2}} cells
Published	10/08/2024	Induration of the skin is a(n) {{c1::late::early/late}} symptom of a type I hypersensitivity reaction
Published	10/08/2024	Histamine release is a(n) {{c1::early::early/late}} feature of a type I hypersensitivity reaction
Published	10/08/2024	A transfusion reaction is an example of which type of hypersensitivity reaction?
Published	10/08/2024	Type III hypersensitivity reactions typically involve Ig{{c1::G}}
Published	10/08/2024	Immune complexes involve which 3 structures "stuck together"?
Published	10/08/2024	What is a classic triad of symptoms of Serum Sickness?
Published	10/08/2024	IL-4 is a key cytokine in type {{c1::I}} hypersensitivity reactions
Published	10/08/2024	Methyldopa can cause which type II hypersensitivity reaction?
Published	10/08/2024	What are 2 mechanisms of cellular destruction in type II hypersensitivity reactions?
Published	10/08/2024	In type III hypersensitivity reactions, attracted Neutrophils will release {{c1::lysosomal enzymes}}
Published	10/08/2024	Which type III hypersensitivity reaction is a local subacute immune complex-mediated hypersensitivity reaction?
Published	10/08/2024	Arthus reaction leads to immune complex formation in the {{c1::skin}}; characterized by edema, necrosis, and activa…
Published	10/08/2024	In type III hypersensitivity reactions, antigen-antibody complexes attract which cell type?
Published	10/08/2024	Serum sickness occurs how long after initial exposure?
Published	10/08/2024	What is a virus that can cause Serum sickness?
Published	10/08/2024	Atopy is a term used to describe {{c1::a predisposition to having hypersensitivity reactions to allergens}}. It refers to the…
Published	10/08/2024	The {{c1::Coombs and Gell classification}} is used to describe the underlying pathology of different hypersensitivity reactions:Type 1: {{c2::IgE…
Published	10/08/2024	When taking a History of someone with a suspected allergy, it is important to ask about (3): {{c1::rashes, swelling, breathing difficulties like a whe…
Published	10/08/2024	What are 3 investigations you can order to test for allergies?{{c1::Skin prick testing}}{{c1::RAST (Radioallergosorbent Test) testing: blood tests for…
Published	10/08/2024	{{c1::Patch testing}} is the most helpful in determining an {{c2::allergic contact dermatitis}} in response to a specific allergen. It is NOT useful f…
Published	10/08/2024	Treatment of allergic reactions is done with:{{c1::Oral Antihistamines e.g cetrizine}}{{c1::Steroids e.g. oral prednisone, topical or IV hydrocortizon…
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