Notes in 02_Scleroderma and Systemic Sclerosis

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Published	02/10/2024	{{c1::Systemic sclerosis}} is an autoimmune inflammatory and fibrotic connective tissue disease.The cause of the condition is unclear. It mo…
Published	02/10/2024	There are two main patterns of disease in Systemic sclerosis: {{c1::Limited cutaneous systemic sclerosis (LCSS)}} {{c1::Diffuse cutaneous systemic scl…
Published	02/10/2024	Features of Limited cutaneous systemic sclerosis (LCSS) ‒ CRESTC – {{c1::Calcinosis}}R – {{c1::Raynaud’s phenomenon}}E – {{c1::oEs…
Published	02/10/2024	{{c1::Calcinosis}} is where calcium deposits build up under the skin. This is most commonly found on the fingertips.
Published	02/10/2024	{{c1::Raynaud’s phenomenon}} is where the fingertips go completely white and then blue in response to even mild cold. It is caused by vasoco…
Published	02/10/2024	{{c1::Oesophageal dysmotility}} is caused by connective tissue dysfunction in the oesophagus. This is commonly associated with swallowing difficu…
Published	02/10/2024	{{c1::Sclerodactyly}} describes the skin changes in the hands as the skin tightens around joints it restricts the range of motion in the joint and red…
Published	02/10/2024	Features of Diffuse cutaneous systemic sclerosis (DCSS){{c1::CREST syndrome}}{{c1::Systemic and pulmonary hypertension}}{{c1::Pulmonary fibr…
Published	02/10/2024	Antibody associated with {{c2::Limited cutaneous systemic sclerosis (LCSS)}}{{c1::Anti-centromere antibodies}}
Published	02/10/2024	Antibody associated with {{c2::Diffuse cutaneous systemic sclerosis (DCSS)}}{{c1::Anti-Scl70 antibodies}}
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