Notes in Osmosis

To Subscribe, use this Key

Status	Last Update	Fields
Published	10/11/2024	Platelet plug formation (primary hemostasis) Platelets have an irregular shape and {{c1::do not::do/do not}} have a nucleus.
Published	10/11/2024	The fourth step of primary hemostasis is {{c1::activation}}, where platelets change shape and express GPIIB/IIIA surface proteins.
Published	10/11/2024	The third step of primary hemostasis is {{c1::adhesion}}, where platelets bind to von Willebrand factors on the exposed collagen.
Published	10/11/2024	{{c1::von Willebrand}} factor stabilizes platelets by forming a bridge between platelets and collagen.
Published	10/11/2024	Platelets contain adhesive proteins that allow them to adhere to the underlying {{c1::vascular endothelium}} and {{c2::fibrin}} mesh at the site of an…
Published	10/11/2024	{{c1::Vascular endothelial}} growth factor is released by platelets in order to stimulate angiogenesis, or the regrowth of blood vessels.
Published	10/17/2024	Platelets promote {{c1::blood coagulation}} by releasing {{c2::thromboplastin}}, which increases circulating amounts of both {{c3::thrombin}} and {{c4…
Published	10/11/2024	Platelets release {{c1::thromboxane A2}}, {{c2::serotonin}}, and {{c3::ADP}} to increase their aggregation in the local environment.
Published	10/11/2024	A decrease in platelet number will {{c1::increase::increase/decrease}} bleeding time.
Published	10/11/2024	The fifth step of primary hemostasis is {{c1::aggregation}}, where platelets stick to each other via {{c2::fibrinogen}}.
Published	10/11/2024	The second step of primary hemostasis is {{c1::exposure}}, where {{c2::subendothelial collagen}} is exposed to the blood during an injury.
Published	10/11/2024	The process of wound healing depends on {{c1::blood clot}} formation in the process of hemostasis.
Published	10/11/2024	Platelets release a growth factor called {{c1::transforming growth factor-beta}}, which promotes the deposition of extracellular matrix tissue into a …
Published	10/11/2024	Platelets release {{c1::platelet-derived}} growth factor in order to direct cell movement during wound healing.
Published	10/17/2024	Fibrinogen is a {{c1::soluble::soluble/insoluble}} clotting factor that is converted into fibrin.
Published	10/11/2024	In the intrinsic pathway of coagulation, {{c1::factor XII}}, the first plasma protein to be activated, has the ability to weakly activate plasmin and …
Published	10/11/2024	In the extrinsic pathway of coagulation, tissue cell trauma exposes blood to {{c1::tissue factor}} to start the cascade.
Published	10/11/2024	The first phase of coagulation involves either the cascade of the intrinsic or extrinsic pathway to activate the common intermediate {{c1::factor X}}.
Published	10/11/2024	In the first phase of coagulation, factor X is activated by factor {{c1::Tissue Factor/VIIa}} complex from the extrinsic pathway.
Published	10/11/2024	In the second phase of coagulation, prothrombin activator catalyzes the conversion of prothrombin into the active enzyme {{c1::thrombin}}.
Published	10/11/2024	In the first phase of coagulation, factor X is activated by factor {{c1::IXa/VIIIa}} complex from the intrinsic pathway.
Published	10/17/2024	Also referred to as factor {{c1::IV}}, {{c2::calcium}} is an inorganic ion necessary for essentially all stages of coagulation.
Published	10/11/2024	In the intrinsic pathway of coagulation, factor {{c1::XII}} is activated by blood circulating over injured internal surfaces of blood vessels, which a…
Published	10/11/2024	In the third phase of coagulation, in the presence of calcium ions, thrombin activates the cross-linking enzyme {{c1::factor XIII (fibrin stabilizing …
Published	10/11/2024	In the first phase of coagulation, once factor X has been activated, it complexes with calcium ions and factor V to form {{c1::prothrombinase}}.
Published	10/11/2024	{{c1::Coagulation}} is a process during hemostasis that reinforces the platelet plug that can be initiated by either the intrinsic pathway or extrinsi…
Published	10/11/2024	The second phase of coagulation, the conversion of prothrombin into the active enzyme thrombin, is referred to as the {{c1::common}} pathway.
Published	10/11/2024	In the extrinsic pathway of coagulation, tissue factor activates factor {{c1::VII}}.
Published	10/11/2024	In the third phase of coagulation, {{c1::fibrin}} molecules polymerize to form long strands to glue platelets together.
Published	10/11/2024	In the third phase of coagulation, thrombin catalyzes the conversion of fibrinogen into {{c1::fibrin}}.
Published	10/11/2024	The process of fibrinolysis begins within {{c1::two days}} and continues over several days to dissolve a clot.
Published	10/11/2024	Large amounts of {{c1::plasminogen}} are incorporated into a forming clot, where it is inactive until appropriate signals reach it to break down the c…
Published	10/11/2024	The enzyme that breaks down fibrin is {{c1::plasmin}}.
Published	10/17/2024	Plasmin is activated from inactive plasminogen by {{c1::tissue plasminogen activator (TPA)}} and urokinase.
Published	10/11/2024	Fibrinolysis is the process of {{c1::breaking down a fibrin clot}} following hemostasis and clot retraction.
Published	10/11/2024	{{c1::Factors II, VII, IX and X, proteins C and S}} are coagulation factors and proteins that require vitamin K as a cofactor for their synthesis.
Published	10/11/2024	{{c1::Vitamin K}} is a vitamin involved in the synthesis of coagulation factors II, VII, IX, X, protein C and protein S.
Published	10/11/2024	{{c1::Vitamin K}} is a fat soluble vitamin that is a cofactor for gamma-carboxylation of glutamic acid residues on various proteins involved in blood …
Published	10/11/2024	Vitamin {{c1::K}} can be given to reverse the effects of warfarin.
Published	10/11/2024	{{c1::Epoxide reductase}} is an enzyme that reduces vitamin K epoxide so that it can act as a cofactor in coagulation factor synthesis.
Published	10/11/2024	The treatment for severe warfarin overdose is {{c1::prothrombin complex concentrate}} along with vitamin K.
Published	10/11/2024	{{c1::Vitamin K}} is a fat soluble vitamin which has an activity that is antagonized by {{c2::warfarin}}.
Published	10/11/2024	{{c1::Vitamin K}} is a fat soluble vitamin synthesized by {{c2::intestinal flora}}.
Published	10/11/2024	{{c1::Vitamin K deficiency bleeding (hemorrhagic disease of the newborn)}} is a hematological disorder seen in neonates with vitamin K deficiency and …
Status	Last Update	Fields