Notes in Lower GI

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Published	02/18/2024	List the polyposis syndromes that are associated with increased risk of colon cancer
Published	02/18/2024	For Familial Polyposis Coli (classic form), what are the: Inheritance pattern and molecular abnormality.
Published	02/18/2024	For Familial Polyposis Coli (classic form), what are the: Clinical features.
Published	02/18/2024	For Familial Polyposis Coli (classic form), what are the: Extracolic manifestations (list at least 4 conditions; 2 of which have malignant potent…
Published	02/18/2024	Familial Polyposis Coli (classic form) is an {{c1::autosomal dominant}} genetic mutation with loss of function mutation of the {{c2::APC tumour supres…
Published	02/18/2024	In AJCC/TNM Stage II node negative adenocarcinoma, list adverse clinicopathological features that would guide the use of adjuvant chemotherapy.
Published	02/18/2024	Describe the microscopic appearance and immunohistochemical profile that would confirm a metastatic colon adenocarcinoma
Published	02/18/2024	In the setting of metastatic CRC: what molecular mutations would you request and what are their clinical significances?
Published	02/18/2024	A fit 45-year-old male presents with a 6-month history of rectal bleeding and abdominal pain. Sigmoidoscopy shows a mid-rectal tumour with the inferio…
Published	02/18/2024	Describe a suitable radiation therapy technique and dose fractionation schedule for long course chemo radiotherapy to the pelvis (cT4N2b with prostate…
Published	02/18/2024	Discuss the options for liver directed traetment in metasatic CRC. Include advantages and disadvantages for each option
Published	02/18/2024	Discuss the indications for neo-adjuvant chemo-radiotherapy in rectal adenocarcinoma
Published	02/18/2024	Discuss optential indications for TNT approach in rectal adenocarcinoma
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