Notes in Blood

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Status	Last Update	Fields
Published	09/08/2023	leukocytes and {{c14::platelets}} (buffy coat)- less than {{c1::1}}% of the volume of whole blood, most of which is taken up by leukocytes&n…
Published	09/08/2023	plasma- makes up approximately {{c2::55}}% of whole blood and is {{c1::acellular}}, meaning it has no cells- about 90% of plasma is {{c3::water}}... r…
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Published	09/08/2023	RBC cytoskeleton*makes biconcave shape → allows {{c2::deformability}} → vertical cytoskeleton interactions is responsible for preventing lipid bi…
Published	09/08/2023	Hemoglobin Oxygenation Saturation- {{c3::sigmoidal}}-shaped curve - 2,3-{{c1::DPG}} stabilizes taut formation favoring {{c2::deoxygenation}}
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Published	09/08/2023	monocytes*kidney-bean shaped nucleus along outer membrane - grow up in bone marrow, circulate in blood - mature into macrophages & {{c1::hist…
Published	09/08/2023	lymphocytes- B cells grow up in {{c6::bone marrow}} - T cells grow up in {{c5::thymus}} *once older, may hang out in lymph nodes / other lymphoid tiss…
Published	09/08/2023	{{c1::platelets}} - shed into the blood from {{c2::megakaryocytes}} in bone marrow- contain membrane glycoproteins:→ {{c3::GPIb}}: {{c6::von Will…
Published	09/08/2023	primary hemostasis and secondary hemostasis1. endothelial injry2. exposure: vWF (= {{c1::Ristocetin}})3. adhesion: GP1b → vWF4. activation: exposes {{…
Published	10/05/2023	blood helps us move nutrients and waste around body, regulate our {{c1::pH}} level, and helps prevent {{c2::infections}}- components of blood can be s…
Published	10/05/2023	erythrocytes- main function is to carry {{c9::oxygen}} to tissues and bring {{c9::carbon dioxide}} to lungs so it can be expired- shaped liked thin {{…
Published	10/05/2023	platelets are also called {{c1::thrombocytes}}the total blood volume of an average adult is about {{c2::6}} LHematocrit is abbreviated {{c3::HCT}}....…
Published	10/05/2023	blood cells can be analyzed histologically by using a common technique called a blood {{c5::smear}} or blood {{c5::film}}→ drop of blood is placed on …
Published	10/05/2023	Erythrocytes- with Wright’s stain, the erythrocytes stain bright {{c1::pink}} or {{c1::red}} because they contain a large amount of {{c2::hemoglobin}}…
Published	10/05/2023	Leukocytes*can be classified into two groups: granulocytes and agranulocytes→ can be be differentiated using light microscopy since the {{c1::granuloc…
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Published	10/05/2023	{{c1::erythropoietin (EPO)}}- hormone (produced in mostly in {{c2::kidney}} and a bit in {{c4::liver}}) that stimulates production of erythrocytes or …
Published	10/05/2023	kidneys- under normal conditions, the kidney cells produce a tiny {{c1::promoter}} called {{c2::hypoxia-inducible factor 1 (HIF1)}}, made up of an alp…
Published	10/05/2023	{{c3::Hemostasis}} is how body prevents blood loss a blood vessel is injured and broken{{c1::Platelet plug}} formation, also called {{c2::primary}} he…
Published	10/05/2023	primary hemostasis: - clumping up of platelets, divided into five steps...- innermost layer of artery = {{c1::endothelium = endothelial cells}}- …
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