Notes in 02 Treatment of Psychotic Disorders

To Subscribe, use this Key

Status	Last Update	Fields
Published	09/03/2024	The most likely atypical antipsychotic to cause tardive dyskinesia is {{c1::risperidone}}, and the least likely is {{c1::clozapine}}
Published	05/07/2024	In addition to mood stabilizers, bipolar disorder may also be treated with {{c1::antipsychotics}}
Published	09/03/2024	Are antipsychotics used to prevent relapse or treat acute mania in bipolar disorder?{{c1::Acute mania, only}}
Published	09/03/2024	What drug class do haloperidol and pimozide belong to?{{c1::Typical antipsychotics (1st generation)}}
Published	09/03/2024	What drug class do trifluoperazine, fluphenazine, thioridazine, and chlorpromazine belong to?{{c1::Typical antipsychotics (1st generation)}}
Published	09/03/2024	Typical antipsychotics exert their effects by blocking the {{c1::D2 dopamine}} receptor
Published	09/03/2024	Typical antipsychotics result in increased {{c1::cAMP::second messenger}}
Published	09/03/2024	The {{c1::high}} potency typical antipsychotics are {{c2::trifluoperazine}}, {{c3::fluphenazine}}, and {{c4::haloperidol}}
Published	09/03/2024	The {{c1::low}} potency typical antipsychotics are {{c2::chlorpromazine}} and {{c3::thioridazine}}
Published	09/03/2024	Are typical antipsychotics effective at treating the positive or negative symptoms of schizophrenia?{{c1::Positive}}
Published	09/03/2024	In addition to schizophrenia, typical antipsychotics are used to treat {{c1::psychosis}} in many conditions (e.g. bipolar disorder, delirium)
Published	09/03/2024	Typical and atypical antipsychotics may be used to treat intractable or distressing tics associated with {{c1::Tourette's}} syndrome
Published	09/03/2024	Typical antipsychotics have {{c1::high}} lipid solubility and thus {{c1::long}} half lives
Published	09/03/2024	Typical antipsychotics are associated with anti-cholinergic effects, such as {{c1::dry mouth}} and {{c2::constipation}}
Published	09/03/2024	Are anti-cholinergic effects more common with high or low potency typical antipsychotics?{{c1::Low potency}}
Published	09/03/2024	Typical antipsychotics are associated with anti-histamine effects, such as {{c1::sedation}}
Published	09/03/2024	Are anti-histamine effects more common with high or low potency typical antipsychotics?{{c1::Low potency}}
Published	09/03/2024	Typical antipsychotics are associated with {{c1::α1}}-adrenergic blockade, which may cause {{c2::orthostatic hypotension}}
Published	09/03/2024	Are anti-α1 effects more common with high or low potency typical antipsychotics?{{c1::Low potency}}
Published	09/03/2024	Typical antipsychotics are associated with {{c1::extrapyramidal symptoms}}, such as acute dystonia, akathisia, and Parkinsonism
Published	09/03/2024	Are extrapyramidal symptoms more common with high or low potency typical antipsychotics? {{c1::High potency}}
Published	09/03/2024	Which extrapyramidal symptoms (e.g. due to antipsychotic use) occur within minutes to days?{{c1::Acute dystonia}}
Published	09/03/2024	Which extrapyramidal symptoms (e.g. due to antipsychotic use) occur within days to months?{{c1::Akathisia (restlessness) and parkinsonism}}
Published	09/03/2024	Which extrapyramidal symptoms (e.g. due to antipsychotic use) occur within months to years?{{c1::Tardive dyskinesia}}
Published	09/03/2024	Typical antipsychotics may cause symptoms of {{c1::prolactin}} excess (e.g. galactorrhea, amenorrhea, gynecomastia)
Published	09/03/2024	What is the most serious adverse effect associated with antipsychotics?{{c1::Neuroleptic malignant syndrome (NMS)}}
Published	09/03/2024	The symptoms of {{c7::neuroleptic malignant}} syndrome may be remembered with the mnemonic "Malignant FEVER":M: {{c1::Myoglobinuria}}F: {{c2::Fever}}E…
Published	09/03/2024	Neuroleptic malignant syndrome is often characterized by a generalized "{{c1::lead-pipe}}" rigidity
Published	09/03/2024	Neuroleptic malignant syndrome may be treated with {{c1::dantrolene*}} or a(n) {{c2::D2}} agonist
Published	09/03/2024	Typical antipsychotics may cause a decreased {{c1::seizure}} threshold
Published	09/03/2024	The typical antipsychotic {{c2::chlorpromazine}} is associated with {{c1::corneal}} deposits
Published	09/03/2024	The typical antipsychotic {{c2::thioridazine}} is associated with {{c1::retinal}} deposits
Published	09/03/2024	What drug class do asenapine, clozapine, olanzapine, and quetiapine belong to?{{c1::Atypical antipsychotics (2nd generation)}}
Published	09/03/2024	What drug class do lurasidone and ziprasidone belong to?{{c1::Atypical antipsychotics (2nd generation)}}
Published	09/03/2024	What drug class does aripiprazole belong to?{{c1::Atypical antipsychotics (2nd generation)}}
Published	09/03/2024	Which atypical antipsychotic is a D2 partial agonist?{{c1::Aripiprazole}}
Published	09/03/2024	Are atypical antipsychotics effective at treating the positive or negative symptoms of schizophrenia?{{c1::Both :)}}
Published	09/03/2024	In addition to schizophrenia, {{c1::atypical}} antipsychotics are used to treat treatment-resistant depression
Published	09/03/2024	What is the treatment of choice for treatment-resistant schizophrenia and schizoaffective disorder?{{c1::Clozapine}}
Published	09/03/2024	Which atypical antipsychotic is used for suicidality in schizophrenia?{{c1::Clozapine}}
Published	09/03/2024	Compared to typical antipsychotics, atypical antipsychotics cause {{c1::less::more/less}} anti-cholinergic side effects
Published	09/03/2024	Compared to typical antipsychotics, atypical antipsychotics cause {{c1::less::more/less}} anti-histamine side effects
Published	09/03/2024	Compared to typical antipsychotics, atypical antipsychotics cause {{c1::less::more/less}} anti-α1 side effects
Published	09/03/2024	Compared to typical antipsychotics, atypical antipsychotics are {{c1::more::more/less}} likely to cause metabolic syndrome
Published	09/03/2024	Atypical antipsychotics may cause metabolic syndrome, which is characterized by {{c1::weight gain}}, {{c2::dyslipidemia}}, and {{c3::hyperglycemia}}
Published	09/03/2024	Which atypical antipsychotics are most associated with metabolic syndrome?{{c1::"-pines" (esp. clozapine and olanzapine)}}
Published	09/03/2024	{{c2::Clozapine}} is an atypical antipsychotic that may cause {{c1::agranulocytosis::hematologic complication}}
Published	09/03/2024	Clozapine is an atypical antipsychotic that may cause {{c1::myocarditis}} and cardiomyopathy (cardiac complications)
Published	09/03/2024	{{c2::Clozapine}} is an atypical antipsychotic associated with a dose dependent risk for {{c1::seizures::neurologic complication}}
Published	09/03/2024	{{c2::Risperidone}} is an atypical antipsychotic that often causes {{c1::hyperprolactinemia::endocrine complication}}
Published	09/03/2024	Compared to typical antipsychotics, atypical antipsychotics are {{c1::less::more/less}} likely to cause extrapyramidal symptoms (EPS)
Published	09/03/2024	Compared to typical antipsychotics, atypical antipsychotics are {{c1::less::more/less}} likely to cause neuroleptic malignant syndrome
Published	09/03/2024	What D2 receptor antagonist is used to treat Huntington disease?{{c1::Haloperidol (typical antipsychotic)}}
Published	09/03/2024	What is the likely diagnosis in a patient with a long history of schizoaffective disorder that presents with lip smacking, sticking out his tongue, an…
Published	09/03/2024	What is the likely underlying pathophysiologic mechanism of tardive dyskinesia?{{c1::D2 receptor upregulation and supersensitivity}}
Published	09/03/2024	What is the likely diagnosis in a patient being treated in the psychiatric ER that develops confusion, high-grade fever, autonomic instability, and mu…
Published	09/03/2024	The primary cause of neuroleptic malignant syndrome is antagonism of {{c1::dopamine (D2)}} receptors in the nigrostriatal pathway
Published	09/03/2024	What features of extrapyramidal symptoms may be treated with reserpine, tetrabenazine, or a switch to an atypical antipsychotic?{{c1::Tardive Dyskines…
Published	09/03/2024	{{c1::Atypical}} antipsychotics may cause metabolic syndrome{{c1::Typical}} antipsychotics may cause extrapyramidal symptoms, NMS and tardive dyskines…
Published	09/03/2024	Patient being treated for hallucinations admitted with fever and confusion. Exam shows diffuse muscle resistance to motion, diaphoresis, tachypnea, dr…
Published	09/03/2024	Which second-generation antipsychotics are most associated with prolonged QTc?{{c1::Risperidone}}{{c1::Ziprasidone}}
Published	09/03/2024	{{c1::Aripiprazole::Atypical antipsychotic}} and {{c2::ziprasidone::atypical antipsychotic}} = ↓ chance of weight gain
Published	09/03/2024	Is tardive dyskinesia reversible?{{c1::Yes, but only if antipsychotic is stopped early}}
Published	09/03/2024	Any patient taking {{c3::antipsychotics::drug class}} should regularly be screened for {{c2::tardive dyskinesia}} using the {{c1::Abnormal Involu…
Published	09/03/2024	Do you need to stop antipsychotics if patient develops neuroleptic malignant syndrome?{{c1::Yes, absolutely}}
Published	09/03/2024	If you start to notice signs of metabolic syndrome in a patient taking antipsychotics, the first step is to {{c1::switch to a different antipsych…
Published	09/03/2024	If you start to notice signs of metabolic syndrome in a patient taking antipsychotics, the second step is to try {{c1::metformin}} or {{c2::topir…
Published	09/03/2024	{{c2::Risperidone}} is an atypical antipsychotic that acts more like a typical antipsychotic at {{c1::high}} doses
Published	09/03/2024	Which atypical antipsychotic is approved for pediatric use?{{c1::Risperidone}}
Published	09/03/2024	Paliperidone is like risperidone, but it acts more like a(n) {{c1::atypical::a/typical}} antipsychotic
Published	09/03/2024	Which antipsychotic is preferentially used to treat psychotic symptoms in Parkinson's disease with dementia?{{c1::Quetiapine}}
Published	09/03/2024	Aripiprazole has low risk of weight gain, but it does cause {{c1::akathisia}}
Status	Last Update	Fields