Notes in ABG

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Published 02/18/2024 14dc68cfc55b4889a0aa229c08c696a7-oa-1
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Published 02/18/2024 Alternative to calculating compensation for metabolic disorders:In a metabolic disorder (both acidosis and alkalosis) with approperiate compensation, …
Published 02/18/2024 General Rule{{c1::Compensation}} never returns pH to normal
Published 02/18/2024 An {{c1::elevated anion gap}} usually indicates the production of a pathologic acid, which is not routinely measured.
Published 02/18/2024 Anion GapIs the {{c1::difference between unmeasured cations and unmeasured anions}}Anion gap = {{c2::[Na] - ([CL] + [HCO3])}}Normal range of anion gap…
Published 02/18/2024 Normal Gap Metabolic Acidosis{{c1::HCO3}} is decreased and {{c1::Cl}} is increased in a {{c1::1:1}} ratio.Is due to {{c2::loss of HCO3}} or {{c2::decr…
Published 02/18/2024 Elevated Gap Metabolic Acidosis{{c1::HCO3}} is decreased and {{c1::Cl}} is normalCaused by:Most commonly {{c3::excess production of an unmeasured acid…
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Published 02/18/2024 Anion Gap Adjustion in HypoalbuminemiaAlbumin is {{c1::charged}} and can alter AGAG adjusted = {{c1::AG measured + 2.5 (4 - [Alb measured])}}
Published 02/18/2024 Triple Disorders DiagnosisThe diagnostic accuracy of an ABG is {{c1::less}} as the level of disorders increasesThus, clinical decisions should only be…
Published 02/18/2024 Maintaining Neutrality During an Elevated Gap AcidosisThere should be a 1:1 ratio between {{c1::↑ anion gap (AG)}} and {{c1::↓ in HCO3}}However some p…
Published 02/18/2024 Delta RatioDelta ratio = {{c1::(AG adjusted - AG normal) / (HCO3 normal - HCO3 measured)}}Used in {{c5::high AG metabolic acidosis to diagnose additio…
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Published 02/18/2024 Mixed acid-base disorders with normal pHJust because different disorders balance each other in the pH, that doesn't mean:{{c1::They share the same imp…
Published 02/18/2024 ecccdb8844e0465eab2d1a216ac621b1-oa-1
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Published 02/18/2024 Impossible to Diagnose Mixed Acid Disorders{{c1::Metabolic acidosis and metabolic alkalosis}}{{c1::Respiratory acidosis and respiratory alkalosis}}
Published 02/18/2024 Having a normal pH despite abnormal levels of pCO2 and HCO3 indicates the presence of {{c1::opposing disorders}}
Published 02/18/2024 08b6e6c8f9cf4d3e8b5946244789ac96-oa-1
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Published 02/18/2024 The delta ratio is not vaild in investigating {{c1::acute metabolic disorders}} in patients with {{c1::severe chronic respiratory disorders}}, as thes…
Published 02/18/2024 Pneumonic for Etiologies of Elevated Gap Metabolic AcidosisK{{c1::etoacidosis}}U{{c1::remia}}L{{c1::actic acidosis}}T{{c1::oxins}}
Published 02/18/2024 Sources of Lactate{{c1::RBS (lack mitochondria)}}{{c2::Non-functioning mitochondria (hypoxia or medications / toxins)}}{{c3::Exercising skeletal muscl…
Published 02/18/2024 Clearane of Lactate{{c1::Liver: is responsible for converting it back to glucose}}{{c2::Kidneys: get involved once lactate levels =/> 5 mmol}}
Published 02/18/2024 Medications causing lactic acidosis
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Published 02/18/2024 KetoacidosisKetoacids (a.k.a keton bodies) are synthesized by the {{c1::liver}} to be used as alternative fuel by cells during periods of {{c1::relati…
Published 02/18/2024 8bd3840adb5b4ff4bf633ca3c746ac33-oa-1
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Published 02/18/2024 Acidosis in Renal FailureThe elevated anion gap metabolic acidosis frequently seen in renal failure occurs for 2 reasons:{{c1::Failure to excrete H+ i…
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Published 02/18/2024 Lactate GapIs {{c1::a large difference between simultaneous POC and laboratory measurements of serum lactate}}Can indicate the presence of {{c2::ethyl…
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Published 02/18/2024 Serum Osmolal GapIs predominantly determined by {{c1::Na+}}, {{c1::HCO3-}}, {{c1::Cl-}}, {{c1::glucose}} and {{c1::urea}}. It is used to identify…
Published 02/18/2024 General indications for the osmolal gap{{c1::Suspected poisoning with unkown toxin}}{{c2::Elevated anion gap in the presence of normal lactate, ketone…
Published 02/18/2024 Limitations of Osmolal Gap in Methanol Injestion
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