Notes in 01_Glomerulonephritis

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Published	02/10/2024	{{c1::Glomerulonephritis}} is {{c2::inflammation of the glomerulus and nephron, associated with nephrotic syndrome (proteinuria), …
Published	02/10/2024	{{c1::Nephrotic and Nephritic Syndromes}} are {{c2::a group of symptoms that show an underlying pathology in the kidney which can be acquired or conge…
Published	02/10/2024	Criteria of {{c2::Nephritic Syndrome}} {{c1::Haematuria (can be microscopic i.e. not visible or macroscopic i.e. visible)}} {…
Published	02/10/2024	Conditions associated with {{c2::Nephritic/Proliferative}} Glomerulonephritis {{c1::IgA nephropathy}} {{c1::Thin Basement Membrane Disease (TBMD)}} {{…
Published	02/10/2024	Presentation of {{c2::IgA Nephropathy}} {{c1::Around 20 yrs}} {{c1::1-2 DAYS Post-Infection (i.e. URTI or GI infection)}} {{c1::Nephritic syndrom…
Published	02/10/2024	Presentation of {{c2::Thin Basement Membrane Disease (TBMD)}} {{c1::Inherited disorder}} {{c1::Microscopic haematuria (incidental finding)}} {{c1::No …
Published	02/10/2024	Presentation of {{c2::Alport Syndrome}}Remembered as {{c1::can’t see}}, {{c1::can’t pee}}, {{c1::can’t hear a bee}} {{c1::Inherited disorder…
Published	02/10/2024	Presentation of {{c2::Goodpasture’s Syndrome}} {{c1::Nephritic syndrome (Haematuria, Oliguria)}} {{c1::Acute renal failure}} {{c1::Haemoptysis}}{{c1::…
Published	02/10/2024	Presentation of {{c2::Rapidly Progessive Glomerulonephritis (RPGN)}} {{c1::Nephritic syndrome (Haematuria, Oliguria)}} {{c1::Acute Illness}} {{c1::Hae…
Published	02/10/2024	Presentation of {{c2::Post Streptococcal Glomerulonephritis (PSGN)}} {{c1::Under 20s: 5-12 years}} {{c1::1-3 WEEKS Post-Infection (i.e. tonsillitis, i…
Published	02/10/2024	Presentation of {{c2::Henoch Schonlein Purpura (HSP)/IgA Vasculitis}} {{c1::5-15 yrs}} {{c1::1-3 DAYS post trigger}} {{c1::Nephritic syndrome (Haematu…
Published	02/10/2024	Criteria of {{c2::Nephrotic Syndrome}} {{c1::ProteinuriaAdults (>3.5g/24hrs or urine protein:creatinine ratio >350 mg/mmol)Children (>2g/24hr…
Published	02/10/2024	Conditions associated with {{c2::Nephrotic/Non-Proliferative}} Glomerulonephritis {{c1::Minimal Change Disease (MCD)}} {{c1::Focal and Segmental …
Published	02/10/2024	Presentation of {{c2::Minimal Change Disease (MCD)}} {{c1::Children (1-10 yrs)}} {{c1::Sudden onset of oedema}} {{c1::Nephrotic syndrome (Proteinuria,…
Published	02/10/2024	Presentation of {{c2::Focal and Segmental Glomerulosclerosis (FSGS)}} {{c1::15-30 yrs}} {{c1::Nephrotic syndrome (Proteinuria, Hypoalbuminaemia, Oedem…
Published	02/10/2024	Presentation of {{c2::Membranous Nephropathy (MN)}} {{c1::50-60 yrs}} {{c1::Nephrotic syndrome (Proteinuria, Hypoalbuminaemia, Oedema)}} {{c1::Majorit…
Published	02/10/2024	Investigations of Glomerulonephritis{{c1::Presenting Symptoms (Age, Oliguria, Fluid retention)}}{{c1::Bloods (Albumin and Lipid levels)}}{{c1::Urine d…
Published	02/10/2024	In the context of Glomerulonephritis, blood tests results of {{c1::Hypoalbuminaemia}} and {{c1::Hyperlipidaemia}} suggest a diagnosis of {{c2::Nephrot…
Published	02/10/2024	Protein findings in urine dipstick and protein:creatinine ratio suggestive of Nephrotic Syndrome are:In an Adult:{{c1::Proteinuria >3.5g/24hrs…
Published	02/10/2024	Protein findings in urine dipstick and protein:creatinine ratio suggestive of Nephrotic Syndrome are:In Children:{{c1::Proteinuria >2g/24hrs}}…
Published	02/10/2024	In the context of Glomerulonephritis, the finding of {{c1::Haematuria}} on urine dipstick is suggestive of {{c2::Nephritic}} Syndrome
Published	02/10/2024	Antibody Associated with {{c2::Goodpasture’s Syndrome}}{{c1::Anti-GBM (glomerular basement membrane) antibodies}}
Published	02/10/2024	Antibody Associated with {{c2::Membranous Nephropathy (MN)}}{{c1::Anti-phospholipase A2 receptor antibody (70% of cases)}}
Published	02/10/2024	Antibodies Associated with {{c2::Type 1 Rapidly Progessive Glomerulonephritis (RPGN)}}{{c1::Goodpasture’s syndrome: Anti-GBM (glomerular basement memb…
Published	02/10/2024	Antibodies Associated with {{c2::Type 2 Rapidly Progessive Glomerulonephritis (RPGN)}}{{c1::Lupus: Anti-double stranded DNA and anti-Smith antibodies}…
Published	02/10/2024	Antibodies Associated with {{c2::Type 3 Rapidly Progessive Glomerulonephritis (RPGN)}}{{c1::VasculitisMicroscopic polyangiitis and Eosinophilic Granul…
Published	02/10/2024	Two Conditions Associated with Acute Renal Failure and HaemoptysisName, Antibody, and Presentation:{{c1::Goodpasture syndromeAntibodies: anti-GBM anti…
Published	02/10/2024	{{c1::Biopsy}} and {{c1::Histology}} is the gold standard for diagnosis of Glomerulonephritis
Published	02/10/2024	Approach to Management of Glomerulonephritis {{c1::Fluid restriction and Diuretics (for Oedema)}} {{c1::ACE inhibitors, ARBs, or CCBs (for Hypertensio…
Published	02/10/2024	Treatment of Minimal Change Disease (MCN) {{c1::Prednisolone}} {{c1::Cyclosporin}} {{c1::Cyclophosphamide}} {{c1::Tacrolimus}} {{c1::Rituximab}}
Published	02/10/2024	Treatment of Focal and Segmental Glomerulosclerosis (FSGS) Usually resistant to {{c1::steroids}} (80% of cases) {{c1::Cyclosporin}} {{c1::Cyclophospha…
Published	02/10/2024	Treatment of Membranous Nephropathy (MN) {{c1::Tacrolimus}} {{c1::Cyclophosphamide}}
Published	02/10/2024	Treatment of IgA Nephropathy {{c1::ACE inhibitors for persistent proteinuria or hypertension}} {{c1::Immunosuppression for moderate-severe disease (if…
Published	02/10/2024	Treatment of Thin Basement Membrane Disease (TBMD) {{c1::If benign, no active treatment}} {{c1::Manage symptoms of chronic kidney disease:Slow down th…
Published	02/10/2024	Treatment of Alport Syndrome{{c1::Manage symptoms of chronic kidney disease:Slow down the disease progression (control diabetes and hypertension, stop…
Published	02/10/2024	Treatment of Post Streptococcal Glomerulonephritis (PSGN) {{c1::Antibiotics}} {{c1::Support renal function (electrolytes, acid-base)}} {{c1::Diuretics…
Published	02/10/2024	Treatment of Goodpasture’s Syndrome {{c1::Steroids +/- Plasma exchange}} {{c1::Cyclophosphamide}}
Published	02/10/2024	Treatment of Rapidly Progessive Glomerulonephritis (RPGN) {{c1::Cyclophosphamide}} {{c1::Rituximab (if vasculitis)}} {{c1::Steroids +/- Plasma exchang…
Published	02/10/2024	Treatment of Henoch Schonlein Purpura (HSP)/IgA Vasculitis {{c1::Symptomatic relief with Analgesia for Joints and Antacids for Gut}} {{c1::Monitor and…
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