Notes in Hemostasis & Bleeding/Clotting (16)

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Status	Last Update	Fields
Published	11/11/2023	Primary regulator of Hematopoiesis
Published	11/11/2023	Primary sequence of hemostasis (3)
Published	11/11/2023	Platelets role in hemostasis
Published	11/11/2023	GP {{c1::VI}} receptor facilitates adhesion by binding {{c2::collagen}}.
Published	11/11/2023	Glycoprotein receptor {{c1::Ib}} is primary receptor of {{c2::adhesion}}
Published	11/11/2023	Glycoprotein receptor {{c1::IIb}} is the primary receptor for aggregation
Published	11/11/2023	Platelets contain {{c1::3}} types of granules which release their contents after platelet activation
Published	11/11/2023	{{c1::Dense (δ)}} granules signal platlets through {{c2::surface receptors}} playing a central role in {{c2::plug formation}}
Published	11/11/2023	{{c1::α}} granules contain mostly proteins and is released following dense granule secretion
Published	11/11/2023	{{c1::vWF}} is synthesized in {{c2::megakaryocytes}} and stored in {{c2::α}} granules
Published	11/11/2023	vWF acts as a carrier for and stabilizes factor {{c1::VIII}}
Published	11/11/2023	{{c1::vWF}} acts as a bridging molecule for platelet adhesion to the subendothelium at sites of vascular injury (GPIb/IX/V receptor)
Published	11/11/2023	vWF, along with {{c1::fibrinogen}}, promotes platelet aggregation to other platelets (GP{{c2::IIb}}/{{c2::IIIa}} receptor)
Published	11/11/2023	{{c2::Scurvy}} & {{c2::Ehlers-Danlos syndrome}} are examples of {{c1::blood vessel wall abnormalities}}
Published	11/11/2023	Pathologies associated with platlet deficiency
Published	11/11/2023	Pathologies associated with platlet dysfunction
Published	11/11/2023	{{c1::Thrombocytopenia}} is a low number of platlets
Published	11/11/2023	In chronic {{c2::Immune Thrombocytopenia Purpura (ITP)}} autoantibodies are directed against glycoprotein {{c1::IIb}}-{{c1::IIIa}} receptor
Published	11/11/2023	{{c2::ITP}} results in {{c1::opsonization}} of {{c1::platelets}}
Published	11/11/2023	{{c2::Thrombotic Microangiopathies}} are disorders involving {{c1::non-immunologic}} destruction of thrombocytes resulting in {{c1::schistocytes}}
Published	11/11/2023	Thrombotic Thrombocytopenic Purpura (TTP) is an example of a {{c1::thrombotic microangiopathy}}  resulting from an inherited {{c2::ADAMTS13}} def…
Published	11/11/2023	HIV-associated Thrombocytopenia
Status	Last Update	Fields