Notes in 05_RBC

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Published	12/28/2023	What are the 4 iron measurements?
Published	12/28/2023	Hookworms can cause what? What are the 3 we should know?
Published	12/28/2023	With a gastrectomy, what happens to iron absorption? Why?
Published	12/28/2023	The initial phase of Iron Deficiency Anemia presents as _______.
Published	12/28/2023	Free Erthyrocyte Protoporphyrin (FEP) in IDA and ACD?
Published	12/28/2023	Dysphagia, IDA, and esophageal webs are the triad characteristic of which syndrome?
Published	12/28/2023	Anemia of Chronic Disease initially presents as a __________ anemia.
Published	12/28/2023	What are these cells called? What material is staining blue, and why has it accumulated?
Published	12/28/2023	Most common form of congenital sideroblastic anemia is due to?
Published	12/28/2023	Lead can denature which two enzymes?
Published	12/28/2023	Lab Findings in Sideroblastic Anemia (4)?
Published	12/28/2023	How would you characterize the differences in globin chain synthesis that cause thalassemias and sickle cell anemia?
Published	12/28/2023	Alpha Thalassemia and Beta Thalassemia are distinguished in one way by the types of mutations which cause them. Describe:
Published	12/28/2023	What is HbH? What condition might it be seen in?
Published	12/28/2023	What will you see on electrophoresis in someone who has alpha thalassemia 4 deletion?
Published	12/28/2023	What results would one expect on β-thalassemia minor hemoglobin electrophoresis?
Published	12/28/2023	Describe the pathophysiology, characteristic imaging, and clinical findings of β-Thalassemia Major
Published	12/28/2023	What is the difference between Megaloblastic Anemia and Macrocytic Anemia?
Published	12/28/2023	Causes of Vitamin B12 deficiency (4)?
Published	12/28/2023	How does B12 deficiency cause neurotoxicity? What 3 tracts are affected?
Published	12/28/2023	What does the reticulocyte count tell you about a normocytic anemia?
Published	12/28/2023	How do you identify reticulocytes on bone marrow biopsy or blood smear?
Published	12/28/2023	Why is the reticulocyte count falsely elevated in an anemic patient? How do we adjust it?
Published	12/28/2023	In a normocytic anemia, how can you tell if it is a result of underproduction or destruction?
Published	12/28/2023	Where does extravascular hemolysis occur?
Published	12/28/2023	What happens to haptoglobin levels in the early stages of an intravascular hemolytic anemia?
Published	12/28/2023	What is an early change in intravascular hemolysis?
Published	12/28/2023	Blood and urine findings in normocytic anemia due to intravascular hemolysis (3):
Published	12/28/2023	What disease demonstrates an increased mean corpuscular hemoglobin concentration (MCHC) and red cell distribution width (RDW)?
Published	12/28/2023	What cells does Parvovirus B19 infect?
Published	12/28/2023	How is hereditary spherocytosis diagnosed?
Published	12/28/2023	What is this?
Published	12/28/2023	Why are sickled cells sickled?
Published	12/28/2023	What is the common vaso-occlusive manifestation of sickle-cell disease that one classically sees in infants?
Published	12/28/2023	Howell Jolly Bodies are seen in which diseases?
Published	12/28/2023	What is Acute Chest Syndrome?
Published	12/28/2023	What is the most common cause of death of adults with sickle cell disease?
Published	12/28/2023	Vasoocclusive crises in the kidneys leads to what pathology?
Published	12/28/2023	Why do people with sickle cell trait have few symptoms? What causes the symptoms they have?
Published	12/28/2023	What is a metabisulfite screen?
Published	12/28/2023	Difference between Hb Electrophoresis in HbS and HbSS?
Published	12/28/2023	What is hemoglobin C?
Published	12/28/2023	What disease is this histological finding associated with? What is the pathogenesis?
Published	12/28/2023	Paroxysmal Nocturnal Hemaglobinuria - describe the pathogenesis:
Published	12/28/2023	Two blood findings and two urine findings in paroxysmal nocturnal hemoglobinuria?
Published	12/28/2023	How do you screen for paroxysmal nocturnal hemoglobinuria?
Published	12/28/2023	Main cause of death in patients with paroxysmal nocturnal hemoglobinuria
Published	12/28/2023	2 complications that can develop over time from paroxysmal nocturnal hemoglobinuria?
Published	12/28/2023	What are the 2 variants of G6PD deficiency?
Published	12/28/2023	How can we screen for and then confirm a diagnosis of G6PD deficiency?
Published	12/28/2023	Besides hereditary spherocytosis, what other disease is associated with spherocytes?
Published	12/28/2023	IgG autoimmune hemolytic anemia is associated with what disorders? What causes it, and what is the treatment?
Published	12/28/2023	IgM Mediated Autoimmune Hemolytic Anemia - pathogenesis and inducing conditions?
Published	12/28/2023	Direct Coombs test vs. Indirect: describe what each detects
Published	12/28/2023	What is a myelophthisic process?
Published	12/28/2023	Is malarial anemia a result of extravascular or intravascular hemolysis?
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