Notes in ACS

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Published	09/08/2024	Acute Coronary Syndromes (1 year of DAPT + lifelong ASA)BARE METAL STENT DAPT: Clopidogrel/prasugrel/ticagrelor + ASA 81mg daily for {{c1::1…
Published	09/08/2024	All patients presenting with ACS will recieve {{c1::nitrates}} unless contraindicated
Published	09/08/2024	Unless contraindicated, all patients presenting with ACS should receive {{c1::ASA}}
Published	09/08/2024	{{c1::Carvedilol and metoprolol }} (2) are BB choices for ACS
Published	09/08/2024	Routine use of beta blockers within 1st 24 hours is not generally recommended unless patient is {{c1::hypertensive}} or has {{c2::refractory…
Published	09/08/2024	Maintenance BB therapy is given as an adjunctive therapy which can be {{c1::peri-MI}} period & {{c1::24h post-MI}} period, onc…
Published	09/08/2024	Tenecteplase (TNK, TNKase) and Alteplase (TPA, Activase) are {{c1::fibrinolytics }}
Published	09/08/2024	{{c1::Fibrinolytic}} are “clot busting”
Published	09/08/2024	{{c1::Altepase}} has Proven valueIndicated for ACS, PE, ischemic stroke
Published	09/08/2024	You will know fibrinolytic therapy has worked when the {{c1::EKG}} normalizes and {{c2::chest pain}}/symptoms resolve
Published	09/08/2024	Contraindications of {{c1::fibrinolytics}}:High risk for {{c2::catastrophic bleeding}}Prior {{c3::ICH}} or known {{c3::cerebrovasc…
Published	09/08/2024	Indications of {{c2::fibrinolytics}} : {{c3::Chest pain}} (or angina equivalent){{c4::<6}} hours (up to 12h is ok)ST eleva…
Published	09/08/2024	Adjuvant therapies during {{c1::PCI}}:{{c3::ASA}}{{c4::anticoagulation}} - UFH, LMWH, or {{c6::bivalirudin}} (cath lab), no fondaparinu…
Published	09/08/2024	PCI needs {{c1::DAPT}}: {{c2::thienopyradine}} / {{c2::non-thienopyridine}} + {{c2::ASA}}
Published	09/08/2024	{{c1::GP IIb/IIIa blockers}} prevent further platelet aggregation
Published	09/08/2024	GP IIb/IIIa blocker are: {{c1::AbciximabEptifibatideTirofiban}}
Published	09/08/2024	after receiving primary PCI for a NSTEMI or STEMI all patients will receive {{c2::DAPT}} consisting of {{c3::ASA}} + {{c4::clopidogrel}}, {{…
Published	09/08/2024	for a patient who had {{c4::stable ischemic heart disease (SIHD)}} and PCI with stent placement and received a {{c3::drug eluting stent…
Published	09/08/2024	both altepase and tenecteplaes have the advantage of {{c1::proven value}}
Published	09/08/2024	{{c1::alteplase}} (fibrinolytic)  is indicated also indicated for ischemic stroke, and PE
Published	09/08/2024	an advantage of tenecteplase is that it is given in a {{c1::bolus}}
Published	09/08/2024	patients who do not qualify for fibrinolytics or PCI are given {{c4::anticoagulation}} with {{c1::UFH}} / {{c1::LMWH}} ({{c2::enoxapa…
Published	09/08/2024	all treatment plans for patients who have ACS include giving patients {{c1::BBs}}, {{c2::ACEIs/ARBs}}, and a {{c3::high intensity statin}} initiated g…
Published	09/08/2024	{{c1::Fondaparinux}} is not the best choice for anticoagulation if the patient is heading the cath lab due to its long half life.
Published	09/08/2024	a {{c1::SL NTG}} should be considered in a treatment plan for ALL patients who have been treated for ACS.
Published	09/08/2024	tirofiban and eptifiban both have {{c1::competitive binding}}(structure) while abciximab has {{c2::steric hindrance}}(structure).
Published	09/08/2024	Abciximab is an {{c1::Ab fragment}} (chemical).
Published	09/08/2024	eptifiban is a {{c1::peptide}} (chemical).
Published	09/08/2024	tirofiban is a {{c1::nonpeptide}} (chemical).
Published	09/08/2024	tirofiban and eptifiban both have {{c1::fast}} reversibility while abcximab has {{c1::slow}} reversibility.
Published	09/08/2024	tirofiban and eptifiban both have {{c1::fast}} return of platelet function while abcximab has {{c1::slow (>48 hours)}} return of platelet func…
Published	09/08/2024	abciximab has a very slow clearance and can be measured for {{c1::10 days}}
Published	09/08/2024	{{c2::eptifiban}} has the shortest half life of its drug class (GP2b/3a) with {{c1::90 minutes}} while {{c2::tirofiban}} has a half life of {{c1::120 …
Published	09/08/2024	patients with a STEMI who need fibrinolytic treatment should receive initially {{c1::Alteplase (TPA, Activase)}} and {{c1::Tenecteplase (TNK…
Published	09/08/2024	patients who had {{c4::ACS}} and PCI with stent placement and received a {{c3::drug eluting stent}} are given DAPT for {{c1::1 yea…
Published	09/08/2024	{{c1::Prasugrel}} is the choice of thienopyrdine for DAPT if a stent was placed in PCI.
Published	09/08/2024	patients with ASA intolerance should be given {{c1::clopidogrel }}
Published	09/08/2024	{{c1::Atorvastatin}} and {{c1::Rosuvastatin}} are high intensity statins that should be given for long term post ACS treatment
Published	09/08/2024	DAPT is only indicated for patients who had a {{c2::PCI}}. For other patients that were treated for ACS, they should receive {{c3::antiplatelet therap…
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