Notes in 05. Asthma Pathophys

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Published	06/26/2023	asthma defintion chronic dz characterized by chronic airway inflammation at least {{c1::partially reversible}} airway obstruction …
Published	06/26/2023	asthma → pathophysiology inflammatory cell infiltrate consists mainly of {{c1::eosinophils}} and {{c1::lymphocytes}}"Sudden death" asth…
Published	06/26/2023	Multiple mechanisms contributing to asthma
Published	06/26/2023	epithelial damage in asthma
Published	06/26/2023	aftermath of inflammation reversibility occurs in most asthma episodes airway returns to {{c1::normal caliber}}flow of air through…
Published	06/26/2023	asthma is chronic inflammatory disorder of the airways {{c1::mast cells}}, eosinophils and lymphocytes infiltrate into airway lining ai…
Published	06/26/2023	risk factors for developing asthma {{c1::genetic}} predisposition hx of atopy airway hyperresponsiveness gender race/ethnicit…
Published	06/26/2023	enviornmental risk factors for development of asthma indoor {{c1::allergens}} outdoor {{c1::allergens}} {{c1::occupational}} sensitizer…
Published	06/26/2023	triggers for acute exacerbation #1 trigger → {{c1::viral respiratory infections}} → URI's allergens irritants sudden or extre…
Published	06/26/2023	acute reaction to triggers irritated airways become more inflamed after {{c1::exposure to stimuli}}muscle layers around {{c1::airway co…
Published	06/26/2023	impairment and risk domains impairment → {{c1::frequency}} and {{c1::intensity}} of symptoms and functional limitations the pt is experiencing or…
Published	06/26/2023	risk factors for death from asthma hx of severe {{c1::exacerbations}}prior intubation for {{c1::asthma}}prior admission to ICU 2 o…
Published	06/26/2023	diagnosis asthma recurrent episodes of cough/wheeze asthma may be present {{c1::without}} a wheeze → {{c1::cough}} may be sole sym…
Published	06/26/2023	spirometry should be performed initial assessment after tx is {{c1::initiated}} and symptoms and PEFs have stabilized at least&nbs…
Published	06/26/2023	peak flow may be performed in all {{c1::moderate/severe}} persistent asthmatics establish a personal best useful in exacerbations …
Published	06/26/2023	<2 years old → when is asthma {{c1::family}} hx of asthma atopy, {{c1::eczema}} perinatal exposure to aeroallergens and irritants&nb…
Published	06/26/2023	asthma predictive index in an infant or young child with {{c1::>3 episodes}} of wheezing in past year 1 of two major criteria OR 2 minor crite…
Published	06/26/2023	asthma misdiagnosis commonly misdiagnosed in kids as {{c1::chronic}} bronchitisrecurrent {{c1::croup}}recurrent URI / pneumonia co…
Published	06/26/2023	asthma children vs adults children present w/ symptoms of {{c1::cough}} +/- noisy or rapid breathing, usually before the age of {{…
Published	06/26/2023	asthma severity assessment children <6 year old often cannot perform reliable PFTs or peak flow measurements older children w/ even …
Published	06/26/2023	long term management of asthma in children: initiation of control therapy symptoms {{c1::>2xweek}}severe exacerbations {{c1::<6 w…
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