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Invaders and Defenders Intro to Immune and Micro
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Published
11/16/2023
Innate Immunity is comprised of _________ and _________. Adaptive immunity is comprised of ____ and ____.
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Complement are the _______ of the innate immune system.
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Complement is made where?
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What happens when complement is triggered? (broadly)
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What is the major role of complement?
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What happens if complement fails?
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What are the 3 encapsulated bacterial infections resulting from failed complement?
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Marines of the immune system: •Crawl through the tissues •Big appetites, big eaters - Digest what they have eaten then present antigen to T cells
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WHat is MHC?
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What if the Phagocytes don’t work?
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If phagocytes fail and you cant kill catalase(+) organisms, what are the names of the catalase(+) organisms what will kill you?
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B cells are the air force of the immune system. they mane and deploy what?
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Recurrent bacterial sinopulmonary infections are caused by what?
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These are examples of what kind of infection?Sinusitis, Ear Infections, Bronchitis, Pneumonias
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S. pneumoniae, H. influenzae, M. catarrhalis are responsible for what kind of infection?
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CD4 T cells are what?
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CD8 T Cells are what?
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Regulatory T cells do what?
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Severe viral infections, fungal infections, and autoimmunity are caused by what?
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What viral infections occur due to T cell failure?
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What fungal infection occurs due to T cell failure? (organism name)
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What determines the gram stain?
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The cell wall assembly is an important _______ target.
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_________ outer membrane contains sugar chains, called lipopolysaccharide (LPS). LPS is a type of Pathogen-Associated Molecular Patterns. (PAMP)
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Flagella -
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Pili or fimbriae -
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Bacteria have specialized...
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________ - External mucoid polysacharide layer avoids immune recognition and phagocytosis
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What cell type accomplishes what is outlined below?•Tight junctions •Mucus barrier •Movement of secretions(Cilia, peristalsis) •Secrete bactericidal c…
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Mucosal epithelia secrete bactericidal compounds including what?
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What do these points describe?•Viruses have specialized molecules that attach to specific host-cell receptors •Only cells that express the receptors c…
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11/16/2023
Complete these examples of viral tropism:- Influenza virus HA binds to ________ - _____ attaches to CCR5 R or CXCR4 R - SARS-CoV-2 spike proteins bind…
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11/16/2023
Catheter-related bloodstream infections and oral biofilm formation is caused by ____________.
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Tracheoesophageal fistula is an example of an __________ defect, allowing pathogens to cross the epithelial barrier.
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Chemotherapy-induced mucositis is an example of a __________ defect, allowing pathogens to cross the epithelial barrier.
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To establish infection, many but not all pathogens invade cells. What are the three methods pathogens may use to invade cells?
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To establish infection, many but not all pathogens invade cells.Give an example of a pathogen that doesn't invade cells
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Bordetella pertussis is the pathogen that causes...
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These are strategies pathogens do to accomplish what?•Intracellular Invasion •Capsules --> avoid phagocytosis •Antigenic variation •Immune modulati…
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How do bacteria / fungi like K. pneumoniae aquire micronutrients like iron?
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