Notes in head.neck

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Published	12/13/2024	The thymus is located in the {{c1::anterior}} mediastinum and is a site of maturation for {{c2::T}} cells.
Published	12/13/2024	The tissue shown is normal {{c1::fetal thymus}} (specifc age group) with:Asterisk = {{c2::medulla}}.Arrow = {{c2::cortex}}.
Published	12/13/2024	Normal thymic T cells begin as {{c1::immature}} T cells at the {{c2::periphery of the outer cortex}} and migrate toward the {{c2::medulla}} where they…
Published	12/13/2024	The term {{c1::thymoma}} refers to tumors of {{c2::thymic epithelium}}.
Published	12/13/2024	The general classifcation of thymomas in order of worsening prognosis include:1. {{c1::Type A thymoma}}.2. {{c1::Type B1 thyoma}}.3. {{c1::Type B2 thy…
Published	12/13/2024	Thymus resection.Most likely diagnosis?{{c1::Type A thymoma}}.
Published	12/13/2024	Thymus resection.Most likely diagnosis?{{c1::Type B3 thymoma}}.
Published	12/13/2024	Before maturity, {{c1::immature T}} cells of the thymus are called {{c2::thymocytes}}.
Published	12/13/2024	The autoimmune disease {{c1::myasthenia gravis}} is associated with follicular hyperplasia within the thymus.
Published	12/13/2024	Thymic {{c3::hyperplasia}} is more of a clinical diagnosis than a pathologic one, as the thymus appears histologically {{c2::normal}}, …
Published	12/13/2024	Thymomas presumably arising from {{c1::medullary}} epithelium are type {{c2::A}}.
Published	12/13/2024	Thymomas presumably arising from {{c1::cortical}} epithelium are type {{c2::B}}.
Published	12/13/2024	Thymomas that are type A differ from type B for immunostains as:1. {{c1::EMA}}: {{c2::positive}} vs {{c2::negative}}.2. {{c1::CK5/6}}: {{c3::negative}…
Published	12/13/2024	The ratio of {{c1::epithelial-to-lymphocytes}} {{c2::increases}} for thymomas B1 to B3.
Published	12/13/2024	{{c1::Type A}} thymoma should {{c2::NOT}} have a significant {{c3::lymphocytic}} cell population.
Published	12/13/2024	Two immunohistochemical markers that are unique to thymic {{c1::squamous}} carcinomas are {{c2::CD5}} and {{c3::CD117 (c-kit)…
Published	12/13/2024	The {{c1::thyroid}} has two basic cell types:1. {{c2::Follicular epithelium}}.2. {{c3::C-cells}}.
Published	12/13/2024	Immunohistochemistry for the {{c1::follicular epithelium}} of thyroid is positive for: 1. {{c2::TTF-1}}. 2. {{c3::PAX8}}. 3. …
Published	12/13/2024	Immunohistochemistry for the {{c1::C-cells}} of thyroid is positive for: 1. {{c2::TTF-1}}. 2. {{c3::Calcitonin}}. 3. {{c4::Ne…
Published	12/13/2024	The thyroid {{c3::epithelium}} encloses small cystic spaces called {{c1::follicles}}, which are filled with gelatinous {{c2::thyro…
Published	12/13/2024	Thyroid resection.Most likely diagnosis?{{c1::Hashimoto thyroiditis}}.
Published	12/13/2024	Key microscopic features of {{c1::Hashimoto thyroiditis}} of the thyroid include:1. Prominent {{c2::lymphoplasmacytic}} infiltrate with {{c3…
Published	12/13/2024	Thyroid resection.Most likely diagnosis?{{c1::Graves disease}}.
Published	12/13/2024	The defining microscopic feature of a thyroid follicular carcinoma is the presence of {{c1::capsular invasion}} or {{c2::vascular …
Published	12/13/2024	Thyroid resection.Most likely diagnosis?{{c1::Hurthle cell adenoma}}.
Published	12/13/2024	Key microscopic features of Hürthle cell adenoma of the thyroid include:1. {{c1::Encapsulated}} lesion (interface).1. Large pink oncocytes2. {{c2::Rou…
Published	12/13/2024	The diagnosis of thyroid papillary carcinoma is based solely on {{c1::nuclear}} features (NOT {{c2::papillary architecture}}).
Published	12/13/2024	Thyroid papillary microcarcinomas are by definition:1. {{c1::Incidental findings}}.2. {{c2::<1 cm}}.
Published	12/13/2024	Thyroid resection.Most likely diagnosis?{{c1::Papillary thyroid carcinoma}}.
Published	12/13/2024	{{c2::Psammoma bodies}} (arrowhead) are almost diagnostic of {{c1::papillary thyroid carcinoma}} in the thyroid or neck lymph node.
Published	12/13/2024	Major risk factors for thyroid papillary carcinoma include:1. {{c1::Radiation}}. 2. {{c2::Thyroiditis}}.
Published	12/13/2024	Unlike thyroid {{c1::follicular}} carcinoma, thyroid {{c1::papillary}} carcinoma does spread to {{c2::lymphatically to lymph …
Published	12/13/2024	Thyroid resection.Most likely diagnosis?{{c1::Medullary carcinoma}}.
Published	12/13/2024	A {{c1::thyroglossal duct cyst}} is a {{c2::midline}} cyst (location) occuring between the {{c3::thyroid}} and the …
Published	12/13/2024	{{c1::Branchial cleft cyst}} is a {{c2::congenital/developmental}} lesion located on the {{c3::anterolateral}} neck that has …
Published	12/13/2024	The most common thyroid cancer in children and adults is {{c1::papillary thyroid carcinoma}}.
Published	12/13/2024	The most common genetic alteration associated with papillary thyroid carcinoma is {{c1::BRAF V600E}}.
Published	12/13/2024	What variant of papillary thyroid carcinoma is depicted?{{c1::Papillary thyroid carcinoma, conventional/classic}}.
Published	12/13/2024	What variant of papillary thyroid carcinoma is depicted?{{c1::Papillary thyroid carcinoma, follicular variant}}.
Published	12/13/2024	What variant of papillary thyroid carcinoma is depicted?{{c1::Papillary thyroid carcinoma, tall cell variant}}.
Published	12/13/2024	What variant of papillary thyroid carcinoma is depicted?{{c1::Papillary thyroid carcinoma, tall cell variant}}.
Published	12/13/2024	What variant of papillary thyroid carcinoma is depicted?{{c1::Papillary thyroid carcinoma, columnar cell variant}}.
Published	12/13/2024	What variant of papillary thyroid carcinoma is depicted?{{c1::Papillary thyroid carcinoma, cribriform-morular variant}}.
Published	12/13/2024	Thyroid resection.Most likely diagnosis?{{c1::Follicular thyroid carcinoma ("mushroom" capsular invasion)}}.
Published	12/13/2024	Follicular thyroid carcinoma is associated with {{c1::Cowden}} syndome.
Published	12/13/2024	Unlike normal parathyroid tissue, a parathyroid adenoma architecturally conains little to no {{c1::fat}}.
Published	12/13/2024	A minority of parathyroid adenoma cases are associated with {{c1::MEN1}} or {{c2::MEN2a}} syndrome.
Published	12/13/2024	Parathyroid glands are composed of 3 main cell types: 1. {{c1::Chief cells}} (main cell type, round central nucleus, clear to amphophilic cy…
Published	12/13/2024	Common primary neoplasms of the parathyroid gland are classified as:1. {{c1::Parathyroid adenoma}}.2. {{c1::Atypical parathyroid adenoma}}.3. {{c1::Pa…
Published	12/13/2024	The 3 main morphologic patterns of anaplastic thyroid carcinoma are:1. {{c1::Sarcomatoid (spindled, "UPS-like")}}.2. {{c2::Giant cell}}.3. {{c3::Epith…
Published	12/13/2024	Anplastic thyroid carcinomas frequently lose expression of {{c1::TTF-1}} and {{c1::CK7}}, but maintain {{c1::PAX8}} expressio…
Published	12/13/2024	"{{c1::Black thyroid}}" usually results secondary to {{c2::minocyline}}/{{c2::tetracycline}} administration and has {{c3::NO}} eff…
Published	12/13/2024	Thyroid resection.Most likely diagnosis?{{c1::Amyloid goiter}}.
Published	12/13/2024	The major causes of amyloid goiter are:1. {{c1::Primary amyloidosis}}.2. {{c2::Secondary amyloidosis}}.3. {{c3::Medullary carcinoma}}.
Published	12/13/2024	{{c1::Graves disease}} is an autoimmune disease characterized by auto-antibodies that stimulate the {{c2::thyroid stimulating hormone recept…
Published	12/13/2024	Key microscopic features of Graves disease include:1. {{c4::Non-branching papillary}} projections.2. {{c1::Scalloping}} of colloid.3. Often {{c2::tall…
Published	12/13/2024	"{{c1::Leukoplakia}}" is a clinical term for {{c2::white plaque}} on a {{c3::mucous membrane}}.
Published	12/13/2024	"{{c1::Erythroplakia}}" is a clinical term for {{c2::red plaque}} on a {{c3::mucous membrane}}.
Published	12/13/2024	For mucous membrane lesions, {{c1::erythro}}-plakia has a higher risk of dysplasia than {{c1::leuko}}-plakia.
Published	12/13/2024	The {{c1::hyphae}} form of Candidiasis can cause tissue invasion symptoms.
Published	12/13/2024	Major HPV-related squamous lesions of the upper aerodigestive tract are:1. {{c1::Verruca vulgaris}}.2. {{c2::Multifocal epithelial hyperplasia}}.3. {{…
Published	12/13/2024	{{c1::Verruca vulgaris}} is a {{c2::benign squamous}} proliferation in the oral cavity caused by {{c3::LOW}}-risk HPV subtypes (e.…
Published	12/13/2024	>{{c2::90}}% of aerodigestive squamous cell carcinomas associated with HPV cases are caused by HPV type {{c1::16}}.
Published	12/13/2024	For the aerodigestive tract, grading {{c1::IS}} performed fo HPV-{{c2::negative}} squamous cell carcinoma and {{c1::IS NOT}} …
Published	12/13/2024	For the aerodigestive tract, the prognosis of HPV-positive squamous cell carcinoma is {{c1::BETTER}} than HPV-negative squamous cell carcoma…
Published	12/13/2024	Major modifiable risk factors for HPV-negative squamous cell carcinoma of the aerodigestive tract are:1. {{c1::Smoking}}.2. {{c2::Alcohol}}.3. {{…
Published	12/13/2024	The most common cause of rhinosinusitis in adults is {{c1::allergies}}.
Published	12/13/2024	The most common cause of rhinosinusitis in children is {{c1::viral upper respiratory tract infections}}.
Published	12/13/2024	Histological features of rhinosinusitis with a predmominate neutrophilic inflammatory infiltrate.Most likely diagnosis?{{c1::Bacterial rhinosinusitis}…
Published	12/13/2024	General histological features of rhinosinusits include:1. {{c1::Submucosal chronic}} inlammation (location and type).2. {{c2::Thickened, hyalinzed}} b…
Published	12/13/2024	Rhinosinusitis with prominant {{c4::eosinophilic}} inflammatory infiltrate.Differential?1. {{c1::Allergic rhinosinusitis}}.2. {{c2::Fungal r…
Published	12/13/2024	{{c1::Granulomatosis with polyangitis}} is a {{c2::vascul}}-itis with {{c3::necrotizing granulomatous}} inflammation that commonly…
Published	12/13/2024	The {{c1::SMARCB1-deficient sinonasal carcinoma}} (aka {{c2::SWI/SNF complex-deficient sinonasal carcinoma}}) is as {{c3::poorly}}…
Published	12/13/2024	SMARCB1-deficient sinonasal carcinoma most commonly occur in the {{c1::nasal ethmoid region}} (anatomical location).
Published	12/13/2024	Immunohistochemistry is critical for SWI/SNF complex-deficient sinonasal carcinomas to demonstrate:1. {{c1::Loss of INI-1}}.2. OR {{c2::BIRG1 protein …
Published	12/13/2024	Genetic alerations associated with SWI/SNF complex-deficient sinonasal carcinoma are:1. {{c1::SMARCB1 inactivation}}.2. OR {{c2::SMARCA4 ina…
Published	12/13/2024	{{c1::Sinonasal undifferentiated carcinoma}} is a {{c2::poorly}}-differentiated carcinoma with {{c3::squamous, glandular, or neuroendoc…
Published	12/13/2024	Important immunohistochemistry markers for a sinonasal undifferentiated carcinoma will be:1. Positive: {{c1::Cytokeratins (e.g. CK AE1/AE3, CK5/6…
Published	12/13/2024	Most cases of sinonasal undifferentiated carcinoma will have genetic alterations involving {{c1::IDH2 codon R172 mutations}}.
Published	12/13/2024	The 3 major types of sinonasal papillomas are:1. {{c1::Exophytic sinonasal papilloma}}.2. {{c2::Inverted sinonasal papilloma}}.3. {{c3::Oncocytic sino…
Published	12/13/2024	The molecular alterations associated with sinonasal papillomas are:1. {{c1::Exophytic sinonasal papilloma}} = {{c2::low risk HPV}}.2. {…
Published	12/13/2024	The risk of transfomation associated with sinonasal papillomas are:1. {{c1::Exophytic sinonasal papilloma}} = {{c2::very low}}.2. {{c1::Inve…
Published	12/13/2024	The classic location associated with sinonasal papillomas are:1. {{c1::Exophytic sinonasal papilloma}} = {{c2::nasal septum}}.2. {{c1::…
Published	12/13/2024	{{c1::Hairy leukoplakia}} is a neoplastic lesion characterized by {{c2::epithelial hyperplasia}}, most commonly on the {{c3::lateral to…
Published	12/13/2024	Key microscopic features of hairy leukoplakia are:1. {{c1::Hyperkeratosis}}.2. {{c2::Parakeratosis}}.3. "{{c5::Ballloon}}" cells in spinous layer.4. {…
Published	12/13/2024	What special investigation is best to confirm the diagnosis of hairy leukoplakia?{{c1::EBER in situ hybridization}}.
Published	12/13/2024	Tongue biopsy from a 72 year-old man.Most likely diagnosis?{{c1::Hairy leukoplakia}}.
Published	12/13/2024	{{c1::Geographic tongue}} is an {{c2::idopathic}} inflammatory condition that clinically appears as {{c4::multiple}}, {{c3::w…
Published	12/13/2024	{{c2::Geographic tongue}} is also known as {{c1::benign migratory glossitis}} and frequently {{c3::self-resolves}} (prognosis…
Published	12/13/2024	30 year-old female with biopsy from "tongue lesions that move".Most likely diagnosis?{{c1::Geographic tongue}}.
Published	12/13/2024	The most common adult malignancy in the sinonasal region is {{c1::squamous cell carcinoma}}.
Published	12/13/2024	An inital immunohistochemistry panel for nasal small round blue cell tumors should include:1. {{c1::CK AE1/AE3}}.2. {{c1::p40}}.3. {{c1::Synaptophysin…
Published	12/13/2024	{{c1::Lymphoepithelial carcinoma}} is an {{c4::un-differentiated}} carcinoma with prominent {{c2::non-neoplastic lymphoplasmacytic…
Published	12/13/2024	Lymphoepithelial carcinoma most commonly affects the {{c1::major salivary glands}} ({{c1::parotid}} > {{c1::submandiubular…
Published	12/13/2024	Lymphoepithelial carcinoma most commonly occurs in {{c1::middle}}-aged patients of {{c2::Asian}} ethnicity/ancestry (especial…
Published	12/13/2024	{{c1::Pleomorphic adenomas}} are the most common tumor of the salivary glands.
Published	12/13/2024	The most common genetic alteration of pleomorphic adenomas are {{c1::PLAG-HMGA2 fusions}}.
Published	12/13/2024	The pyramidal lobe of the thyroid is a remnant of the {{c1::thyroglossal duct}}.
Published	12/13/2024	Partoid mass from a 72 year-old female.Most likely diagnosis?{{c1::Oncocytoma}}.
Published	12/13/2024	Oncocytomas of the head and neck most commonly occur in the {{c1::parotid gland}} (anatomical location) in {{c2::eldery}} (age gro…
Published	12/13/2024	Common fungal infections of the sinonasal/nasopharyngeal tract include?1. {{c1::Aspergillosis}}.2. {{c3::Mucormycosis}}.3. {{c2::Rhinosporidosis}}.
Published	12/13/2024	Key histologic features of {{c4::aspergillus orgranisms}} include:1. {{c1::Thin hyphae}}.2. {{c2::Acute angle branching (45 degrees)}}.3. {{…
Published	12/13/2024	Aspergillus sinonasal/nasopharyngeal infections come in 3 major forms of infection:1. {{c1::Allergic fungal sinusitus}}.2. {{c2::Aspergillus mycetoma …
Published	12/13/2024	Key histologic features of mucormycosis include:1. {{c1::Large diameter}}.2. {{c2::"Ribbon"-like non-septated hyphae}}.3. {{c3::Branching at 90 degree…
Published	12/13/2024	Mucormycosis classically causes infections in patients with {{c2::diabetic ketoacidosis}} and/or are {{c1::immunocomprised}}.
Published	12/13/2024	{{c2::Olfactory neuroblastomas}} are a malignant {{c3::neuroectodermal}} neoplasm confined to the {{c1::cribriform plate}} (a…
Published	12/13/2024	Cribriform plate resection from a 54 year-old male.Most likely diagnosis?{{c1::Olfactory neuroblastoma}}.
Published	12/13/2024	Olfactory neuroblastomas have the following key immunohistochemistry profile:1. {{c1::Synapophysin}}, {{c1::chromogranin}}, {{c1::CD56}} = diffuse pos…
Published	12/13/2024	A simple differential for oncocytic salivary gland neoplasms would include:1. {{c1::Warthin tumor}}.2. {{c1::Oncocytoma/oncocytic carcinoma}}.3. {{c1:…
Published	12/13/2024	The key microscopic features of a Warthin tumor include:1. {{c3::Bilayered oncocytic}} epithelium.2. Underlying {{c2::mature lymphoid}} tissue.3. {{c1…
Published	12/13/2024	Warthin tumors are strongly linked to {{c2::smoking}} and almost exclusively arise in the {{c1::parotid gland}} (anatomical locati…
Published	12/13/2024	50 year old Caucasian female with a thyroid mass.Most likely diagnosis?{{c1::Papillary thyroid carcinoma}}.
Published	12/13/2024	The tall cell variant of papillary thyroid carcinoma has cells that are {{c1::3}}x as tall as it is wide.
Published	12/13/2024	65 year old female with a rapidly growing neck mass.Most likely diagnosis?{{c1::Anaplastic thyroid carcinoma}}.
Published	12/13/2024	Genetic alterations associated with anaplasic thyroid carcinoma include (main genes):1. {{c1::P53}}.2. {{c2::BRAF}}.3. {{c3::PTEN}}.4. {{c4::RAS}}.
Published	12/13/2024	50 year old female with left neck mass.Most likely diagnosis?{{c1::Medullary thyroid carcinoma}}.
Published	12/13/2024	Medullary thyroid carcinoma has frequent {{c1::RET}} mutations and occasional {{c2::RAS}} mutations.
Published	12/13/2024	Medullary throid carcinoma is associated with {{c1::MEN2A}} syndrome (~{{c2::30}}% of cases).
Published	12/13/2024	What is a common and key microscopic feature of medullary thyroid carcinoma is depicted?{{c1::Frequent stromal amyloid}}.
Published	12/13/2024	What is a common and key microscopic feature of medullary thyroid carcinoma is depicted?{{c1::Occasional pseudoinclusions}}.
Published	12/13/2024	Key microscopic features of a medullary thyroid carcinoma include:1. {{c1::Variable}} tumor architecture (solid, lobular, trabecular, and/or insu…
Published	12/13/2024	Secretory carcinoma is associated with molecular alterations involving {{c1::ETV6-NTRK3 gene fusions}} (most common) or {{c2::ETV6…
Published	12/13/2024	{{c5::Secretory carcinomas}} have immunohistochemistry results that are positive for:1. {{c1::S100}}.2. {{c3::SOX10}}.3. {{c2::Mammoglobin}}.4. {…
Published	12/13/2024	Parotid mass from a 52 year-old male.Most likely diangosis?{{c1::Secretory carcinoma}}.
Published	12/13/2024	Secretory carcinomas usually present as an {{c1::asymptomatic}} {{c2::parotid gland}} mass in a {{c3::middle}}-aged {{c4::mal…
Published	12/13/2024	40 year-old male with fixed painful salivary gland mass.Most likely diagnosis?{{c1::Acinic cell carcinoma}}.
Published	12/13/2024	Acinic cell carcinomas have immunohistochemistry/special stains positive for:1. {{c1::SOX10}}.2. {{c2::DOG-1}}.3. {{c3::S100}} (occasionally).4. {{c4:…
Published	12/13/2024	Acinic cell carcinoma most commonly occurs in the {{c1::parotid gland}} (anatomical location).
Published	12/13/2024	The genetic alteration associated with acininc cell carcioma is translocation {{c2::t(4;9)(q13;q31)}} which drives nuclear overexpression of…
Published	12/13/2024	Canalicular adenomas almost always occur on the {{c1::upper lip}} (anatomical location).
Published	12/13/2024	Key microscopic features of a salivary gland cellular adenoma include:1. {{c1::Encapsulated}} (interface).2. {{c2::Mono}}-phasic tumor of {{c3::b…
Published	12/13/2024	HPV-positive squamous cell carcinoma of the upper digestive tract has a strong predilection for the {{c1::oropharynx}} (predominately the&nb…
Published	12/13/2024	Key microscopic features of HPV-positive squamous cell carcinoma include:1. {{c1::Non-keratinizing}} (keratin).2. {{c2::Basaloid}} appearenc…
Published	12/13/2024	Squamous papillomas of the upper aerodigestive tract are usually associated with HPV types {{c1::6}} and {{c1::11}} with {{c2::rar…
Published	12/13/2024	If there are multiple {{c1::squamous papillomas}} of the upper aerodigestive tract, you should consider {{c2::recurrent respiratory pap…
Published	12/13/2024	Female child with a "lesion" in her mouth.Most likely diagnosis?{{c1::Squamous papilloma}}.
Published	12/13/2024	{{c1::Condyloma acuminatum}} are {{c2::anogenital}} warts (anatomical location) most commonly caused by HPV types {{c3::6}} a…
Published	12/13/2024	Patient presenting with painful ulcers in mouth.Most likely diagnosis?{{c1::Herpes simplex virus mucositis}}.
Published	12/13/2024	Key microscopic features of herpes simplex virus mucosal infection include:1. {{c1::Classic ground glass}} intranuclear inclusions.2. 3Ms = {{c2:…
Published	12/13/2024	Herpes simplex virus infects {{c1::epithelial}} cells and {{c1::ganglion}} cells with predilection of {{c2::type 1}…
Published	12/13/2024	{{c2::Inflammatory sinonasal polyps}} are non-neoplastic swellings of the sinonasal mucosa secondary to {{c1::chronic sinusitus}} that …
Published	12/13/2024	{{c4::Pituitary adenomas}} are {{c1::benign}} neoplasms of the {{c2::anterior pituitary}} that are usually primary to the&nbs…
Published	12/13/2024	Mucoepidermoid carciomas are histologically composed of 3 cellular components:1. {{c1::Mucinous cells}}.2. {{c2::Squamous cells}}.3. {{c3::"Intermedia…
Published	12/13/2024	The most common malignant neoplasm of the salivary glands is {{c1::mucoepidermoid carcioma}}.
Published	12/13/2024	Mucoepidermoid carciomas commonly have genetic alterations inolving {{c1::MAML2 fusions}}.
Published	12/13/2024	Salivary gland tumors that are generally ALWAYS considered high-grade include (treated aggressively):1. {{c1::Salivary duct carcinoma}}.2. {{c4::Neuro…
Published	12/13/2024	{{c1::Adenomatous hyperplasia}} of the thyroid is clinically {{c2::multinodular goiter}} due to {{c3::follicular epithelial hyperp…
Published	12/13/2024	Normal salivary gland.Circle 1 depicts {{c1::salivary ducts}}.
Published	12/13/2024	Normal salivary gland.Circle 2 depicts {{c1::salivary acini}}.
Published	12/13/2024	Normal salivary gland.Circle 3 depicts {{c1::fat}}.
Published	12/13/2024	If there is {{c1::symmetric enlargement}} of salivary glands with NO {{c1::discrete mass}}, the diagnosis of {{c2::sialadenosis}}&…
Published	12/13/2024	{{c1::IgG4-related sialadenitis}}, aka "{{c3::Kuttner}} tumor" is a multi-organ {{c2::autoimmune}} disorder that can form tumefactive l…
Published	12/13/2024	Key microscopic features of {{c1::IgG4 related siladenitis}} include:1. {{c2::Storiform}} architecture/pattern of {{c3::fibrosis}}.2. Dense …
Published	12/13/2024	{{c1::Warthin}} tumors are {{c2::benign}} lesions that likely develop due to {{c3::transformation of salivary gland tissue entrapp…
Published	12/13/2024	The aspirated fluid of a Warthin tumor is typicall described as being like "{{c1::motor oil}}" ({{c1::viscous}}, {{c1::dark}}).
Published	12/13/2024	{{c1::Warthin tumors}} were previously known as {{c2::papillary cystadenoma lymphatosum}}.
Published	12/13/2024	Pertinent negative immunohistochemistry markers for a salivary gland secretory carcinoma include:1. {{c2::DOG1}}.2. {{c1::Squamous}} markers (e.g. {{c…
Published	12/13/2024	Key microscopic features of a salivary gland {{c4::secretory}} carcinoma include:1. Tubular, papillary, or cystic growth.2. {{c3::Eosinophic…
Published	12/13/2024	Parotid gland resection.Most likely diagnosis?{{c1::Secretory carcinoma}}.
Published	12/13/2024	A salivary gland {{c1::striated duct adenoma}} is a {{c2::benign}} tumor that is {{c3::rare}} (frequency) and is associa…
Published	12/13/2024	Parotid gland resection.Most likely diagnosis?{{c1::Striated duct adenoma}}.
Published	12/13/2024	Key microscopic features of a salivary gland striated duct adenoma include:1. {{c1::Well-circumscribed, encapsulated}} interface.2. Tightly-packed {{c…
Published	12/13/2024	Immunohistochemistry results supportive of a salivary gland striated duct adenoma include:1. Positive {{c3::cytokeratin}} (general).2. …
Published	12/13/2024	Key microscopic features of a salivary gland acinic cell carcinoma include:1. Variable architecture (solid to cystic to follicular).2. {{c6::Large}}, …
Published	12/13/2024	Salivary gland {{c4::acinic cell carcinoma}} are malignant tumors composed of {{c3::acinar}} cells that are generally {{c2::N…
Published	12/13/2024	{{c1::PASD}} or {{c1::mucicarmine}} stains can help highlight the {{c2::mucinous}} cells of a mucoepidermoid carcinoma.
Published	12/13/2024	Salivary gland adenoid cystic carcinoma occurs in the {{c1::major and minor}} salivary glands that is associated with persistent {{c2::…
Published	12/13/2024	Key microscopic features of salivary gland adenoid cystic carcinoma include:1. {{c5::Infiltrative}} interface.2. {{c6::Tubular}}, {{c6::cribriform}}, …
Published	12/13/2024	Parotid gland mass fine-needle aspiration.Most likey diagnosis?{{c1::Adenoid cystic carcinoma}}.
Published	12/13/2024	Grading of salivary gland adenoid cystic carcinoma requires reporting of the {{c1::percent solid component (>30% bad)}}.
Published	12/13/2024	Salivary gland adenoid cystic carcinoma is graded as:1. Low-grade: mostly {{c1::myoepithlial}} cells (IHC: positive {{c1::p40}} and {{c1::SMA}}).2. Hi…
Published	12/13/2024	Parotid gland mass resection from a 50 year-old female.Most likely diagnosis?{{c1::Pleomorphic adenoma}}.
Published	12/13/2024	Eyelid plaque biopsy from a 40 year-old make.Most likely diagnosis?{{c1::Xanthelasma (++ lipid-laden macrophages adjacent to vessels)}}.
Published	12/13/2024	Parotid gland resection from 50 year-old female.Most likely diagnosis?{{c1::Adenoid cystic carcinoma}}.
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