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01_Hyperparathyroidism
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Published
02/10/2024
{{c2::Primary hyperparathyroidism}} is the {{c1::presence of parathyroid gland tumour or hyperplasia which leads to excess PTH production, causin…
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02/10/2024
{{c2::Secondary hyperparathyroidism}} is {{c1::where there is vitamin D insufficiency or chronic renal failure, leading to excess PTH produc…
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02/10/2024
{{c2::Tertiary hyperparathyroidism}} is {{c1::hyperplasia of the parathyroid glands due to prolonged secondary hyperparathyroidism, causing parathyroi…
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02/10/2024
Causes of {{c2::Primary}} Hyperparathyroidism{{c1::Parathyroid gland pathology (i.e. tumour)}}
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02/10/2024
Causes of {{c2::Secondary}} Hyperparathyroidism {{c1::Low vitamin D}}{{c1::Chronic Kidney Disease (CKD)}}
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02/10/2024
Causes of {{c2::Tertiary}} Hyperparathyroidism {{c1::Long-standing secondary hyperparathyroidism (Parathyroid Hyperplasia)}}
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02/10/2024
Presentation of {{c1::Hypercalcaemia}} can be remembered by the mnemonic:{{c2::Renal stones, Painful bones, Abdominal groans, and Psychiatric moans}}
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02/10/2024
Presentation of {{c2::Hypercalcaemia}}:{{c1::Renal (i.e. kidney stones, nephrogenic diabetes insipidus)}} {{c1::Bones (i.e. pain, osteoporosis, f…
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02/10/2024
Investigations of Hyperparathyroidism {{c1::PTH and Calcium levels}} {{c1::U&Es (assess electrolyte disturbances and renal function)}} {{c1:…
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02/10/2024
Levels of PTH and Calcium{{c2::Primary}} Hyperparathyroidism{{c1::High}}, {{c1::High}}
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02/10/2024
Levels of PTH and Calcium{{c2::Secondary}} Hyperparathyroidism {{c1::High}}, {{c1::Low/Normal}}
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02/10/2024
Levels of PTH and Calcium{{c2::Tertiary}} Hyperparathyroidism {{c1::High}}, {{c1::High}}
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02/10/2024
95% of patients with {{c1::Multiple Endocrine Neoplasia 1 (MEN 1)}} have primary hyperparathyroidism
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02/10/2024
Treatment of Primary Hyperparathyroidism is by {{c1::Surgery: removing the tumour}}{{c1::If surgery unsuitable: usage of Cinacalcet}}
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02/10/2024
Treatment of Secondary Hyperparathyroidism is by correcting the {{c1::vitamin D deficiency}} or managing {{c1::kidney impairment}}
Published
02/10/2024
Mechanism of Action of {{c1::Cinacalcet}} {{c2::It is a calcimetic i.e. mimics the effect of calcium on the calcium sensing receptor on Chief cel…
Published
02/10/2024
Treatment of Tertiary Hyperparathyroidism {{c1::Surgery: removing part hyperplastic parathyroid tissue to return the PTH to an appropri…
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