Notes in Building Blocks

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Status	Last Update	Fields
Published	08/30/2023	DNA (test)
Published	08/30/2023	Three main components of the ECM
Published	08/30/2023	Two main adhesive proteins
Published	08/30/2023	Three main structural/fibrous proteins
Published	08/30/2023	Proteoglycans are composed of  a {{c2::protein core}} that’s attached to chains of sugars called {{c1::glycosaminoglycans.}}
Published	08/30/2023	Proteoglycans trap {{c1::water molecules}} due to the {{c2::negative charge}} of its GAG chains and create a cushioning gel-like substance.
Published	08/30/2023	Elastin is commonly found in {{c1::ligaments, blood vessels, skin, and lungs}} (regions of the body).
Published	08/30/2023	Keratin is mostly found in our {{c1::hair and nails.}} (parts of the body)
Published	08/30/2023	Type I Collagen is found in the {{c1::Bone, Skin, and Tendons}}.
Published	08/30/2023	Type II collagen is found in our {{c1::Cartilage}}.
Published	08/30/2023	Type III collagen is found in {{c1::Reticulin and Blood vessels.}}
Published	08/30/2023	{{c1::Adhesive proteins}} stick the individual cells together and organize the tissue into a neat structure.
Published	08/30/2023	Collagen is made and released into the {{c1::extracellular space}} as its precursor, {{c2::procollagen.}}
Published	09/07/2023	Formation of collagen (pathway)
Published	08/30/2023	Type IV collagen is found in the {{c1::Basement membrane.}}
Published	08/31/2023	In insulin, the A and B chains are held together by {{c1::disulfide}} bonds
Published	08/31/2023	Sickle cell disease is caused by a substitution of {{c1::valine}} in the place of glutamic acid, increasing the {{c2::hydrophobicity}} of the hemoglob…
Published	08/31/2023	In cystic fibrosis, the CFTR gene regulates the transport of {{c1::chlorine ions}}
Published	08/31/2023	Hydroxyurea increases the concentration of {{c1::fetal hemaglobin}} to treat {{c2::sickle-cell anemia. }}
Published	08/31/2023	Glycosylation
Published	08/31/2023	Hydroxylation of proline
Published	08/31/2023	Carboxylation
Published	08/31/2023	There are {{c1::two}} high-energy {{c1::anhydride}} bonds in ATP.
Published	08/31/2023	{{c1::AZT}} is a modified version of {{c1::thymine}} used to treat {{c2::HIV}} via {{c2::chain termination. }}
Published	09/05/2023	{{c1::Ciprofloxacin}} treats {{c1::anthrax}} by inhibiting {{c2::bacterial gyrase}} (analog of topoisomerase) which prevents {{c2::DNA replication}}
Published	08/31/2023	Functions of p53 (summarized)
Published	09/05/2023	{{c2::Imatinib (Gleevec)}} inhibits {{c1::kinase activity}} in cancer cells and prevents {{c1::cell proliferation}}
Published	08/31/2023	Two main factors increasing cell membrane fluidity
Published	08/31/2023	Key events of prophase
Published	08/31/2023	Key events of metaphase
Published	08/31/2023	Key events of anaphase
Published	08/31/2023	Prophase I subdivisions
Published	08/31/2023	Key event of Leptotene
Published	08/31/2023	Key events of zygotene
Published	08/31/2023	Key events of pachytene
Published	08/31/2023	Key events of diplotene
Published	08/31/2023	Key events of Diakinesis
Published	08/31/2023	Mismatch repair pathway
Published	08/31/2023	Non-homologous end joining pathway
Published	08/31/2023	Homologous end joining pathway
Status	Last Update	Fields