Notes in MP.S1.L02. Infections of CVS(Lec)

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Status	Last Update	Fields
Published	10/21/2024	Infection of CVSMost common cause: {{c1::Bacteria}}
Published	10/21/2024	Infection of CVSThese diseases are caused by the constant shedding of organisms into the blood and cause persistent {{c1::low-grade fever}}
Published	10/21/2024	Infection of CVS (5 conditions){{c1::EndocarditisMyocarditisRheumatic Heart Disease (RHD) ThrombophlebitisEndarteritis}}
Published	10/21/2024	Infective EndocarditisPreviously referred to as {{c1::Bacterial Endocarditis}}
Published	10/21/2024	Infective EndocarditisAffects: {{c1::Heart valves}} {{c1::Septa of the heart}} {{c1::Cardiac sinus}}
Published	10/21/2024	Infective EndocarditisCardiac abnormalities increase the risk of developing IE such as (6):{{c1::Artificial (prosthetic) valves Bicuspid aortic v…
Published	10/21/2024	Infective EndocarditisPathogenesis (5){{c1::Endothelium of the Heart is Altered by the Infecting Pathogens Colonization of the Endothelium by the…
Published	10/21/2024	Infective EndocarditisPathogenesis{{c1::Endothelium of the Heart is Altered by the Infecting Pathogens::what step in pathogenesis}} Microorganism…
Published	10/21/2024	Infective EndocarditisPathogenesis{{c1::Colonization of the Endothelium by the Infecting Pathogens::what step in pathogenesis}} Facilitated by th…
Published	10/21/2024	Infective EndocarditisPathogenesis{{c1::Deposition of Platelets and Fibrin::what step in pathogenesis}} The turbulence of blood flow around the d…
Published	10/21/2024	Infective EndocarditisPathogenesisDeposition of Platelets and FibrinThe circulating pathogens adhere to the fibrin and plateletsCausing an inflammator…
Published	10/21/2024	Infective EndocarditisPathogenesisMesh VegetationThrombotic “mesh” composed of {{c1::platelets}}, {{c1::fibrin}}, and {{c1::inflammatory cells}} form
Published	10/21/2024	Infective EndocarditisPathogenesis{{c1::Mesh Vegetation}}Protects pathogens from host defense and antibiotics
Published	10/21/2024	Infective EndocarditisPathogenesis{{c1::Embolus}}As mature vegetation causes alteration in the cardiac endothelium, it obstructs blood flow and increa…
Published	10/21/2024	Infective EndocarditisClinical Presentation{{c1::Acute}} Infective Endocarditis Infection of a previously normal heart valve
Published	10/21/2024	Infective EndocarditisClinical Presentation{{c1::Acute}} Infective Endocarditis Infection by a highly virulent organism that rapidly produces des…
Published	10/21/2024	Infective EndocarditisClinical Presentation{{c1::Acute}} Infective Endocarditis Rapid onset of fever, chills, weakness, lassitudePhysical examina…
Published	10/21/2024	Infective EndocarditisClinical Presentation{{c1::Acute}} Infective Endocarditis Rapid destruction of valves frequently resulting in fatal cardiac…
Published	10/21/2024	Infective EndocarditisClinical Presentation{{c1::Subacute}} Infective Endocarditis Caused by organisms with lower virulence
Published	10/21/2024	Infective EndocarditisClinical Presentation{{c1::Subacute::Acute or Subacute}} Infective Endocarditis Cause insidious infections of deformed valv…
Published	10/21/2024	Infective EndocarditisClinical Presentation{{c1::Subacute}} Infective Endocarditis Low-grade feverweight lossnight sweats
Published	10/21/2024	Infective EndocarditisClinical Presentation{{c1::Subacute}} Infective Endocarditis Most common organism that causes it: {{c2::Viridans strep…
Published	10/21/2024	Infective EndocarditisClinical Presentation{{c1::Acute}} Infective Endocarditis Most common organism that causes it: {{c2::Staphylococcus au…
Published	10/21/2024	Infective Endocarditis{{c1::Modified Duke Criteria}}Diagnostic Critera for Infective Endocarditis
Published	10/21/2024	Infective EndocarditisModified Duke CriteriaPathologic Criteria (2){{c1::Microorganisms, demonstrated by culture or histologic examination in vegetati…
Published	10/21/2024	Infective EndocarditisModified Duke CriteriaMajor Clinical Criteria (3){{c1::Blood culture(s) positive for a characteristic organism or persistently p…
Published	10/21/2024	Infective EndocarditisModified Duke CriteriaMinor Clinical Criteria (5){{c1::Predisposing heart lesion or intravenous drug use}}{{c1::Fever}}{{c1::Vas…
Published	10/21/2024	Infective EndocarditisModified Duke CriteriaClinical Criteria: Definitive DiagnosisHow many major and minor criteria{{c1::2 major}}{{c1::1 major, 3 mi…
Published	10/21/2024	Infective EndocarditisModified Duke CriteriaClinical Criteria: Possible IEHow many major and minor criteria{{c1::1 major, 1 minor}}{{c1::3 minor}}
Published	10/21/2024	Infective EndocarditisModified Duke Criteria{{c1::Janeway lesions}}small, erythematous, or hemorrhagic macular, non tender lesion on the palms and sol…
Published	10/21/2024	Infective EndocarditisModified Duke Criteria{{c1::Osler nodes}}small, tender, subcutaneous nodules that develop in the pads of the digits or occasiona…
Published	10/21/2024	Infective EndocarditisModified Duke Criteria{{c1::Roth spots}}oval retinal hemorrhages with pale centers
Published	10/21/2024	Infective Endocarditis{{c1::Viridans streptococci}}Most common pathogen (50-60%) in damaged or abnormal valves
Published	10/21/2024	Infective Endocarditis{{c1::Viridans streptococci}}Normal component of oral cavity flora
Published	10/21/2024	Infective Endocarditis{{c1::Viridans streptococci}}Most common pathogenic organism in patients who underwent {{c2::dental procedures}}, predisposed to…
Published	10/21/2024	Infective Endocarditis{{c1::Viridans streptococci}}Gram-{{c2::positive::+ or -}} cocci in {{c3::pairs or chains::pairs or chains, or clusters}}Catalas…
Published	10/21/2024	Infective EndocarditisViridans streptococciDifferentiates them from staphylococci{{c1::Catalase-negative}}
Published	10/21/2024	Infective EndocarditisViridans streptococciDifferentiates viridans streptococci from other species of streptococci{{c1::Colonies are NOT soluble in bi…
Published	10/21/2024	Infective EndocarditisViridans streptococciGrowth is NOT inhibited by Optochin meansThere will be a {{c1::clear area}} surrounding it
Published	10/21/2024	Infective Endocarditis{{c1::Staphylococcus aureus}}Responsible for 20-30% of cases and affects healthy or deformed valves
Published	10/21/2024	Infective Endocarditis{{c1::Staphylococcus aureus}}Most common pathogen causing IE in {{c2::intravenous drug abusers::what group of people}}
Published	10/21/2024	Infective Endocarditis{{c1::Staphylococcus aureus}}Gram-{{c2::positive::+ or -}} cocci in {{c3::grape-like clusters::pairs or chains, or clusters}}Cat…
Published	10/21/2024	Infective Endocarditis{{c1::Staphylococcus aureus}}Culture: grow readily on most bacteriologic media under {{c2::aerobic}} or {{c2::microaerophil…
Published	10/21/2024	Infective Endocarditis{{c1::Staphylococcus aureus}}Colonies: Round Smooth Raised Glistening {{c2::Gray to deep golden yellow:…
Published	10/21/2024	Infective EndocarditisStaphylococcus aureusAll staphylococci are Catalase-{{c1::positive::+ or -}}
Published	10/21/2024	Infective EndocarditisStaphylococcus aureusFrom all staphylococci, only Staphylococcus aureus is Coagulase-{{c1::positive::+ or -}}
Published	10/21/2024	Infective Endocarditis{{c1::Staphylococci}}Slowly ferment many carbohydrates, producing {{c2::lactic acid}}
Published	10/21/2024	Infective Endocarditis{{c2::Staphylococci}}Relatively resistant to:{{c1::drying}}{{c1::heat}}{{c1::10% sodium chloride}}
Published	10/21/2024	Infective Endocarditis{{c2::Staphylococci}}Can withstand {{c1::50}} degrees celsius
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic Structures{{c1::Peptidoglycan}}{{c1::Protein A}}{{c1::Polysaccharide capsule}}{{c1::Clumping factor}}{{c1…
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic Structures{{c1::Peptidoglycan}}Rigid exoskeleton of the cell wall Anchors the adhesins Elicits …
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic StructuresPeptidoglycanRigid exoskeleton of the cell wall Anchors the {{c1::adhesins}}
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic StructuresPeptidoglycanElicits production of {{c2::IL-1}} and {{c2::opsonic antibodies monocytes}} C…
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic StructuresPeptidoglycanHave {{c1::endotoxin}}-like activity Activate {{c2::complement}}
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic Structures{{c1::Teichoic acid}}Cross-linked to the {{c2::peptidoglycan}} and can be {{c3::antigenic}}&nbs…
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic Structures{{c1::Teichoic acid}}Important in {{c2::cell wall}} metabolism {{c3::Anti-teichoic acid}} …
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic Structures{{c1::Protein A}}Bacterial surface proteins in S. aureus strains
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic Structures{{c1::Protein A}}{{c2::Microbial surface components recognizing adhesive matrix molecules (MSCR…
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic Structures{{c1::Clumping factor}}Binds nonenzymatically to {{c2::fibrinogen}} and {{c2::platelets}}, yiel…
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic Structures{{c1::Polysaccharide complex}}Seen in S. aureus strains which inhibit {{c2::phagocytosis}}
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic Structures{{c1::Peptidoglycan}} assembly is the target of:{{c2::beta lactam::what drug types}}{{c2::glyco…
Published	10/21/2024	Infective EndocarditisStaphylococciAntigenic StructuresAnti-teichoic acid antibodies Detectable by {{c1::gel diffusion}}
Published	10/21/2024	Infective EndocarditisStaphylococciEnzymes and Toxins (6){{c1::CatalaseCoagulaseClumping FactorHemolysinsOther enzymesPanton-Valentine Leukocidin}}
Published	10/21/2024	Infective EndocarditisStaphylococciEnzymes and Toxins (6){{c1::Coagulase}} binds to {{c3::prothrombin}} Together they become enzymatically a…
Published	10/21/2024	Infective EndocarditisStaphylococciEnzymes and Toxins (6)Other enzymes {{c1::hyaluronidase}} or {{c2::spreading factor}}
Published	10/21/2024	Infective EndocarditisStaphylococciEnzymes and Toxins (6){{c2::Hemolysins}}regulated by {{c1::agr (accessory gene regulator)}}
Published	10/21/2024	Infective EndocarditisStaphylococciEnzymes and Toxins (6)Hemolysins{{c1::α-hemolysin}}acts on broad spectrum of eukaryotic cell membranes
Published	10/21/2024	Infective EndocarditisStaphylococciEnzymes and Toxins (6)Hemolysins{{c1::β-toxin}}degrades {{c2::sphingomyelin}}
Published	10/21/2024	Infective EndocarditisStaphylococciEnzymes and Toxins (6)Hemolysins{{c1::δ-toxin}}disrupts {{c2::biologic membranes}}
Published	10/21/2024	Infective EndocarditisStaphylococciEnzymes and Toxins (6)Hemolysins{{c1::γ-hemolysin}}leukocidin that lyses white blood cells
Published	10/21/2024	Infective EndocarditisStaphylococciEnzymes and Toxins (6){{c1::Panton-Valentine Leukocidin}}kill white blood cells The two components designated …
Published	10/21/2024	Infective EndocarditisStaphylococciEnzymes and Toxins (6){{c1::Panton-Valentine Leukocidin}}important virulence factor for {{c2::community-acquired MR…
Published	10/21/2024	Infective EndocarditisStaphylococciResistanceβ lactamase productionmake organism resistant to many {{c1::penicillin}}
Published	10/21/2024	Infective EndocarditisStaphylococciResistance{{c1::mecA}} and {{c1::mecC}} genesresistance to:{{c2::nafcillin}}{{c2::methicillin}}{{c2::oxacillin}}
Published	10/21/2024	Infective EndocarditisStaphylococciResistance{{c1::Vancomycin}} resistancePlasmid-mediated resistance
Published	10/21/2024	Infective EndocarditisStaphylococciResistance{{c1::Vancomycin}} resistanceIncreased cell wall synthesis and alterations in the cell wall
Published	10/21/2024	Infective EndocarditisStaphylococciResistanceVancomycin resistanceSusceptible to vancomycin: MIC is {{c1::2}} mg/mL or less Intermediate Suscepti…
Published	10/21/2024	{{c1::Prosthetic Valve}} EndocarditisOccuring in {{c3::1 to 2 months}} after surgeryTypically caused by skin flora:{{c2::Staphylococcus aureus}} …
Published	10/21/2024	{{c1::Prosthetic Valve}} EndocarditisOccuring after {{c2::1 year or more}} after surgery: Provide the infecting agent:{{c3::Staphylococcus aureus…
Published	10/21/2024	Prosthetic Valve EndocarditisS. epidermidisCoagulase {{c2::negative::+ or -}}{{c1::non}}-hemolytic
Published	10/21/2024	Prosthetic Valve Endocarditis{{c2::S. epidermidis}}Colonies are usually {{c1::gray::color}} to {{c1::white::color}} in primary isolation May be r…
Published	10/21/2024	Prosthetic Valve EndocarditisOther causes:{{c1::Enterococci HACEK Group}}{{c1::Gram negative bacilli}}{{c1::Fungi}}
Published	10/21/2024	Prosthetic Valve EndocarditisEnterococci (HACEK group){{c1::Haemophilus}}{{c1::Actinobacillus}}{{c1::Cardiobacterium}}{{c1::Eikenella}}{{c1::Kingella}…
Published	10/21/2024	Prosthetic Valve Endocarditis{{c5::Enterococci}} Previously classified as Group {{c1::D}} streptococciPart of normal enteric flora{{c2::Non}}-hem…
Published	10/21/2024	Prosthetic Valve EndocarditisEnterococci Grow in {{c1::6.5% NaCl}} More resistant to penicillin G and many isolates are vancomycin-resistant…
Published	10/21/2024	Infective EndocarditisComplications Formation of {{c1::immune complexes(glomerular antigen antibody complex deposition) causing glomerulonephriti…
Published	10/21/2024	Infective EndocarditisTreatment {{c2::Empirical IV}} before shifting to a pathogen-specific treatment for {{c3::4-6::range}} weeks once a pathoge…
Published	10/21/2024	{{c2::Myocarditis}}Most commonly caused by {{c1::Coxsackie viruses A and B::what virus and what are the two types}} and other {{c1::enteroviruses}}
Published	10/21/2024	{{c1::Myocarditis}}Clinical FeaturesFlu-like symptoms ({{c3::7-14::range}} days)Dyspnea, chest pain, arrhythmia Infections may be fatal to {{c2::…
Published	10/21/2024	MyocarditisCoxsackievirusesUnder the {{c1::Picornaviridae}} family and the subgroup of {{c1::enterovirus}}Divided into 2 groups, A and B, having diffe…
Published	10/21/2024	MyocarditisCoxsackievirusesIncubation period of {{c1::2 to 9::range}} days
Published	10/21/2024	MyocarditisCoxsackievirusesLaboratory diagnosisRecovery of virusIsolated from {{c1::throat washings}} during the first few days of illness and from {{…
Published	10/21/2024	MyocarditisCoxsackievirusesLaboratory diagnosis{{c1::Inoculated into the tissue cultures and suckling mice}}{{c1::Nucleic acid detection}} {{c1::…
Published	10/21/2024	Myocarditis{{c1::Coxsackie B viruses}}Most commonly identified causative agent of viral heart disease in humans
Published	10/21/2024	MyocarditisImportant Properties of PicornavirusesVirion{{c1::Icosahedral::shape}}28-30 nm in diametercontains {{c2::60}} subunits
Published	10/21/2024	MyocarditisImportant Properties of PicornavirusesGenomeSingle-stranded RNAlinear{{c2::positive::+ or -}} sense7.2-8.4 kb in sizemolecular weight 2.5 m…
Published	10/21/2024	MyocarditisImportant Properties of PicornavirusesProteinsFour major polypeptides cleaved from a large precursor polyprotein. Surface capsid prote…
Published	10/21/2024	MyocarditisImportant Properties of Picornaviruses{{c2::Envelope}}{{c1::None::where}}
Published	10/21/2024	MyocarditisImportant Properties of PicornavirusesReplication{{c1::Cytoplasm}}
Published	10/21/2024	MyocarditisImportant Properties of PicornavirusesOutstanding characteristicFamily is made up of many {{c1::enterovirus}} and {{c1::rhinovirus}} types …
Published	10/21/2024	MyocarditisImportant Properties of PicornavirusesCoxsackievirusesFamily is made up of many {{c1::enterovirus}} and {{c1::rhinovirus}} types that infec…
Published	10/21/2024	MyocarditisPicornaviridae Family  Includes 2 major groups of human pathogen; {{c1::enteroviruses}} {{c1::rhinoviruses}}
Published	10/21/2024	MyocarditisCoxsackievirusesRecovery of virus {{c1::NOT done, very difficult to isolate}}
Published	10/21/2024	MyocarditisCoxsackievirusesNucleic acid detection through {{c1::PCR}}
Published	10/21/2024	MyocarditisCoxsackievirusesSerology Neutralizing antibodies appear {{c1::early::early or late}} in the course of infectionSpecific for infecting …
Published	10/21/2024	MyocarditisManagement{{c1::Symptomatic}} treatment Vaccine: {{c2::NONE}}Antiviral drugs: {{c2::NONE}}
Published	10/21/2024	MyocarditisManagementSymptomatic treatment Patient’s activity is limited to preserve cardiac function or patients with heart failure may require …
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseManagementSymptomatic treatment Patient’s activity is limited to preserve cardiac function or patients…
Published	10/21/2024	{{c1::Rheumatic Fever and Rheumatic Heart Disease}}Acute, immunologically mediated multisystem inflammatory disease Classically occurring a few w…
Published	10/21/2024	{{c1::Rheumatic Fever and Rheumatic Heart Disease}}Most serious sequelae of {{c2::Streptococcus pyogenes}} infection Results from host immune res…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseClinical FeaturesThe onset is often preceded by {{c1::S. pyogenes pharyngitis::what disease}} {{c2::1-5}} w…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseSigns and symptoms:Fevermalaisemigratory {{c1::nonsuppurative::suppurative or nonsuppurative}} polyarthriti…
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Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseS. PyogenesMorphology and IdentificationGram-{{c1::positive::+ or -}} cocci arranged in chains Grow in…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseS. PyogenesMorphology and IdentificationProduce capsules composed of {{c1::hyaluronic acid}} Contains …
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseS. PyogenesGrowthEnergy is obtained from the utilization of {{c1::glucose}} with {{c1::lactic acid}} as the…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseS. PyogenesGrowthGrowth and hemolysis are aided by incubation in {{c2::10}}% CO2 Grow best at {{c1::37…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseS. PyogenesMorphology and Identification{{c1::Hyaluronic acid}} impedes {{c3::phagocytosis}} {{c2::Lip…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseS. PyogenesAntigenic Structure{{c1::M Protein}} (major virulence factor) Filamentous structure anchore…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseS. PyogenesAntigenic StructureM Protein (major virulence factor) Resist phagocytosis by inhibiting act…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseS. PyogenesCan a person get repeated infection of S. pyogenes{{c1::YES, there are {{c2::>150}} types of …
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseToxins and Enzymes (6){{c1::Pyrogenic Exotoxins (Erythrogenic Toxin)HyaluronidaseHemolysinsDeoxyribonucleas…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseToxins and Enzymes{{c1::Streptokinase (Fibrinolysin)}}Transforms plasminogen of the human plasma to plasmin…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseToxins and Enzymes{{c1::Deoxyribonucleases}}Degrades DNA Facilitate the spread of streptococci in tiss…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseToxins and Enzymes{{c1::Hyaluronidase}}Aids in spreading infecting microorganisms ({{c2::spreading factor}}…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseToxins and Enzymes{{c1::Streptolysin O}}Hemolytically-active in the {{c2::reduced::oxidized or reduced}} st…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseToxins and Enzymes{{c1::Antistreptolysin O}}Blocks hemolysis by streptolysin O
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseToxins and EnzymesAntistreptolysin O (ASO) titerExcess of {{c2::160-200}} units is considered abnormally hi…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseToxins and Enzymes{{c1::Streptolysin S}}Responsible for the hemolytic zones around streptococcal colonies g…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseToxins and EnzymesStreptokinase is administered {{c1::intravenously}}
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseToxins and Enzymes{{c1::Three::how many}} antigenically distinct Streptococcal pyrogenic exotoxins: {{c1::A…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseDiagnostic and Laboratory Tests{{c1::Smears}}{{c1::Serologic Tests}}{{c1::Antigen Detection Tests}}{{c1::Cu…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseDiagnostic and Laboratory TestsCulture Blood agar plates Incubation in 10% CO2 often speeds hemol…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseDiagnostic and Laboratory TestsSerologic TestsASOanti-{{c1::DNase B}} and antihyaluronidase, antistrep…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseTreatment{{c1::Penicillin G}}{{c1::Macrolides}}{{c1::Antistreptococcal chemoprophylaxis}}
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseTreatment{{c1::Penicillin G}}All S. pyogenes are susceptible
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseTreatment{{c1::Macrolides}}For patients with Penicillin allergyExample:{{c2::Erythromycin}}{{c2::Clindamyci…
Published	10/21/2024	Rheumatic Fever and Rheumatic Heart DiseaseTreatmentAntistreptococcal chemoprophylaxisOne injection of {{c1::benzathine penicillin}} & intramuscul…
Published	10/21/2024	Infectious Vasculitis{{c1::Thrombophlebitis }}Inflammation in the veins
Published	10/21/2024	Infectious Vasculitis{{c1::Endarteritis}}Inflammation in arteries
Published	10/21/2024	Infectious VasculitisUsually caused by direct invasion of bacteria or fungi{{c1::Aspergillus}}{{c1::Mucor}}
Published	10/21/2024	Infectious VasculitisVascular infections Can weaken arterial walls Culminate in {{c1::mycotic}} aneurysms Can induce thrombosis and {{c…
Published	10/21/2024	Infectious VasculitisVascular invasion can be part of a localized tissue infection Less commonly, can arise from {{c1::hematogenous}} spread of m…
Published	10/21/2024	Infectious VasculitisExamples of {{c1::localized tissue infection}} include: Bacterial pneumonia Adjacent abscesses
Published	10/21/2024	Infectious VasculitisExamples of {{c1::hematogenous spread of microorganisms}} include: Septicemia Embolization from infective endocarditis
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