Notes in 09_pulm

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Published 12/28/2023 A child presents with nasal polyps - what diseases should he be worked up for (2)?
Published 12/28/2023 What is the triad of aspirin-intolerant asthma?
Published 12/28/2023 In what population are angiofibromas classically seen? What is the classic presentation?
Published 12/28/2023 A Chinese adult male presents with large cervical lymph nodes and masses in the nasopharynx. Biopsy reveals pleomorphic keratin-positive epithelial ce…
Published 12/28/2023 Most common cause of acute epiglottitis?
Published 12/28/2023 Most common cause of laryngotracheobronchitis (croup)?
Published 12/28/2023 What causes laryngeal papilloma (a benign tumor of the vocal cord)?
Published 12/28/2023 What is the difference in presentation of laryngeal papilloma in adults vs. children?
Published 12/28/2023 What are the risk factors for laryngeal carcinoma?
Published 12/28/2023 What are the two most common causes of lobar pneumonia?
Published 12/28/2023 A lobar pneumonia in a patient with increased risk for aspiration is suspicious for what organisms (4)? 
Published 12/28/2023 What are the functions of type I and II pneumocytes? 
Published 12/28/2023 What are the gross phases of lobar pneumonia? Describe each: 
Published 12/28/2023 Describe the radiologic appearance of bronchopneumonia: 
Published 12/28/2023 What are the 5 most common causes of bronchopneumonia and what disease processes are each organism associated with? 
Published 12/28/2023 What is the most common cause of interstitial (atypical) pneumonia? Who is most at risk?Common complications (2)?
Published 12/28/2023 Most common cause of interstitial (atypical) pneumonia in infants?
Published 12/28/2023 What is the most common cause of interstitial (atypical) pneumonia in patients taking post-transplant immunosuppressive therapy?
Published 12/28/2023 Which lobe is most commonly involved in cases of aspiration pneumonia?
Published 12/28/2023 Compare primary TB  and secondary TB in terms of:Initiating factorsLocationCharacteristic lesions/gross pathological featuresSymptoms
Published 12/28/2023 What are the key spirometry readings for chronic obstructive pulmonary disease?TLC:FEV1:FVC:FEV1/FVC ratio:
Published 12/28/2023 What is the definiton of chronic bronchitis? What is it highly associated with?
Published 12/28/2023 What is the Reid index? What is diagnostic value for chronic bronchitis?
Published 12/28/2023 What type of cell undergoes hypertrophy in chronic bronchitis?
Published 12/28/2023 4 clinical features of chronic bronchitis:
Published 12/28/2023 What is the underlying physical/functional pathophys of emphysema? 
Published 12/28/2023 Emphysema is caused by an imbalance of proteases and antiproteases. What are the 2 most common causes, and how do they create these imbalances? 
Published 12/28/2023 What type of emphysema does alpha-1 antitrypsin (A1AT) deficiency result in?
Published 12/28/2023 What is the most common clinically relevant mutation causing A1AT deficiency? How do heterozygotes and homozygotes present? 
Published 12/28/2023 5 clinical features of emphysema: 
Published 12/28/2023 What are 2 key histopathological findings in the sputum of asthmatics?
Published 12/28/2023 What are 6 causes of bronchiectasis? 
Published 12/28/2023 2 serious complications of bronchiectasis? 
Published 12/28/2023 Bronchiectasis symptoms (3)?
Published 12/28/2023 What are the key spirometry reading for restrictive diseases?TLC:FEV1:FVC:FEV1/FVC ratio:
Published 12/28/2023 What is the key cytokine involved in the pathogenesis of idiopathic pulmonary fibrosis?
Published 12/28/2023 The patient from whom this lung specimen was taken likely had what disease?
Published 12/28/2023 What is Caplan syndrome?
Published 12/28/2023 What is anthracosis?
Published 12/28/2023 What are the 4 most common pneumoconioses?
Published 12/28/2023 What is the only pneumoconiosis that increases the risk for tuberculosis infection?
Published 12/28/2023 Differential diagnosis for noncaseating granulomas in the lung, hilar lymph nodes and systemic organs?
Published 12/28/2023 What is a ferruginous body?
Published 12/28/2023 Any disease involving noncaseating granulomas can induce hypercalcemia. Why? 
Published 12/28/2023 How is pulmonary HTN defined? 
Published 12/28/2023 Plexiform lesions are characteristic of what? 
Published 12/28/2023 What is the gene that is classically associated with familial forms of primary pulmonary HTN? What does it do?
Published 12/28/2023 What is the hallmark of acute respiratory distress syndrome (ARDS)? How do they arise? 
Published 12/28/2023 What are the 2 key treatments for ARDS?
Published 12/28/2023 What immune cell is key to the pathogenesis of ARDS and what does it do? List some initiating causes of ARDS:
Published 12/28/2023 Recovery from ARDS may be complicated by what? Why does this happen? 
Published 12/28/2023 What is the main component of surfactant? (& other name)
Published 12/28/2023 What happens to the amniotic lecithin:sphingomyelin ratio as the fetal lungs mature? What is the target ratio? 
Published 12/28/2023 What are 3 factors that neonatal respiratory distress syndrome (NRDS) is associated with? 
Published 12/28/2023 What are the 2 key mutagens found in cigarette smoke?
Published 12/28/2023 What are 3 exposures that greatly increase risk of developing lung cancer? 
Published 12/28/2023 What is the key finding on imaging for lung cancer? What does the subsequent work-up entail?
Published 12/28/2023 What are two non-cancer causes of "coin lesions" seen on X-ray?
Published 12/28/2023 What are the 3 paraneoplastic syndromes associated with small cell carcinoma of the lung?
Published 12/28/2023 Which neuroendocrine cells does small cell carcinoma stem from?
Published 12/28/2023 What is the paraneoplastic syndrome associated with squamous cell carcinoma of the lung?
Published 12/28/2023 What are 2 characteristic histological features of squamous cell carcinoma of the lung?
Published 12/28/2023 What is the most common tumor in non-smokers as well as in female smokers?
Published 12/28/2023 What is the location of the following lung tumors: small cell, squamous cell, adenocarcinoma, large cell, bronchioloalveolar carcinoma?
Published 12/28/2023 Which lung cancer classically presents as a pneumonia-like consolidation on imaging (and has an excellent prognosis)?
Published 12/28/2023 Which type of cell does a bronchioloalveolar carcinoma arise from? What is that cell's function?
Published 12/28/2023 Which lung tumor is chromogranin positive?
Published 12/28/2023 Which type of lung tumor classically forms a polyp-like mass in the bronchus?
Published 12/28/2023 What is more common to the lung: primary tumor or metastasis?
Published 12/28/2023 To where does lung cancer most commonly metastasize?
Published 12/28/2023 Which two lung cancers are not in any way related to smoking?
Published 12/28/2023 What is a Pancoast tumor and what can it cause?
Published 12/28/2023 What type of pneumothorax shifts the trachea to the side of the collapse?
Published 12/28/2023 What type of pneumothorax shifts the trachea to the opposite side of the collapse?
Published 12/28/2023 What does mesothelioma present with (3 symptoms)? 
Published 12/28/2023 Diagnosis?
Published 12/28/2023 Type of pneumonia? 
Published 12/28/2023 Type of Pneumonia? 
Published 12/28/2023 Type of pneumonia? 
Published 12/28/2023 What type of pneumonia? 
Published 12/28/2023 What type of pneumonia?
Published 12/28/2023 What organism can be seen in this specimen stained with an AFB stain?
Published 12/28/2023 What pathology is this histological specimen taken from the lung indicative of?
Published 12/28/2023 What is depicted in the histology specimen taken from the lung seen below? What disease would this be found in?
Published 12/28/2023 What can be seen on this histological specimen taken from the lung? Underlying disease? 
Published 12/28/2023 What is this?
Published 12/28/2023 This radiograph is characteristic of what condition?
Published 12/28/2023 What condition might this radiograph be indicative of? 
Published 12/28/2023 What lung cancer is this?
Published 12/28/2023 What cancer?
Published 12/28/2023 What lung cancer?
Published 12/28/2023 What lung cancer?
Published 12/28/2023 What lung cancer? 
Published 12/28/2023 What type of lung cancer is this? 
Published 12/28/2023 What is this lung tumor? 
Published 12/28/2023 What type of lung tumor is this?
Published 12/28/2023 What type of lung cancer is this? What type of stain?
Published 12/28/2023 What pathology can be seen on this radiograph?
Published 12/28/2023 What lung malignancy?
Published 12/28/2023 What disease might this histopathological specimen taken from the bronchi be indicative of? 
Published 12/28/2023 What disease is this histolopathologic specimen indicative of? 
Published 12/28/2023 What can be seen in this histology specimen from the liver? 
Published 12/28/2023 What is the most common cause of rhinitis? 
Published 12/28/2023 An inflammatory infiltrate in the nasopharynx in a patient with asthma and eczema indicates what pathology? 
Published 12/28/2023 This radiograph is supsicious for what respiratory tract pathology? 
Published 12/28/2023 What are vocal cord nodules composed of? 
Published 12/28/2023 What are the 3 patterns of pneumonia commonly seen on X-ray? 
Published 12/28/2023 How does atypical pneumonia present, both clinically and radiographically? 
Published 12/28/2023 Atypical pneumonia in the elderly is most commonly caused by what infectious entity? 
Published 12/28/2023 A veternarian comes to you with a high fever and symptoms of atypical (interstitial) pneumonia. What organism should be on your differential? 
Published 12/28/2023 Asthma is often associated with what 3 things? 
Published 12/28/2023 Asthma is driven by what immune cells? 
Published 12/28/2023 What 3 cytokines largely drive the pathogenesis of asthma? 
Published 12/28/2023 Describe the overall general pathogenesis of asthma: 
Published 12/28/2023 What is the treatment for idiopathic pulmonary fibrosis? 
Published 12/28/2023 What are some causes of secondary pulmonary fibrosis? 
Published 12/28/2023 Though the exact etiology is unknown, what likely causes sarcoidosis? 
Published 12/28/2023 What is the classic histological structure seen in sarcoidosis? 
Published 12/28/2023 What are the two most common sites of involvement in sarcoidosis? 
Published 12/28/2023 What are 3 less commonly involved tissues involved in sarcoidosis? 
Published 12/28/2023 In silicosis, where do fibrotic nodules typically form?
Published 12/28/2023 4 clinical features/lab values of sarcoidosis: 
Published 12/28/2023 What 3 processes lead to artery thickening in cases of pulmonary hypertension? 
Published 12/28/2023 What are the cardiac sequelae of pulmonary hypertension? 
Published 12/28/2023 What are 3 causes of secondary pulmonary HTN?
Published 12/28/2023 What is the most common lung tumor in male smokers? 
Published 12/28/2023 Into what 2 general categories is lung carcinoma typically divided? How do these classifications affect treatment? 
Published 12/28/2023 Pleural involvement is classically seen with which lung tumor? 
Published 12/28/2023 What is superior vena cava syndrome? 
Published 12/28/2023 What two nerves can be involved with a central lung tumor? 
Published 12/28/2023 Does lung cancer often present early or late? 
Published 12/28/2023 How does a spontaneous pneumothorax commonly arise, and in whom? 
Published 12/28/2023 How does a tension pneumothorax arise? 
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