Notes in pharma

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Published	11/05/2024	major types of drugs to treat thrombotic disease (based on mechanism)
Published	11/05/2024	Delete
Published	11/05/2024	types of parenteral anticoagulants
Published	11/05/2024	types of oral anticoagulants
Published	11/05/2024	types of new oral anticoagulant
Published	11/05/2024	types of indirect thrombin inhibitors (parenteral)
Published	11/05/2024	chemically heparin is formed of what?
Published	11/05/2024	pH and charge on heparin
Published	11/05/2024	heparin is effective in {{c1::both}} (vivo/vitro)
Published	11/05/2024	mechanism of anticoagulant action of heparin
Published	11/05/2024	pharmacological effects of heparin
Published	11/05/2024	delte
Published	11/05/2024	mechanism of action of plasma clearing effect of heparin
Published	11/05/2024	classification of antiplatelets according to mechanism of action
Published	11/05/2024	antiplatelets that act on COX enzyme
Published	11/05/2024	antiplatelets that increases cAMP
Published	11/05/2024	Effect on platelet induced by PGI2 attachment
Published	11/05/2024	low dose aspirin ranges from {{c1::75}} to {{c1::325 mg}}/day
Published	11/05/2024	{{c1::clopidogrel}} or {{c1::dipyridamole}} anticoagulants may be combined with aspirin
Published	11/05/2024	mechanism of antiplatelet effect of aspirin
Published	11/05/2024	{{c1::epoprostenol}} is a PGI2 analogue
Published	11/05/2024	mechanism of action of PGI2 analogue (epoprostenol)
Published	11/05/2024	theraputic effects of epoprostenol
Published	11/05/2024	epoprostenol effect is {{c1::short acting}} (long-acting/short-acting)
Published	11/05/2024	mode of delivery of epoprostenol
Published	11/05/2024	mechanism of dipyridamole & cilostazol
Published	11/05/2024	side effects of aspirin
Published	11/05/2024	mode of delivery of dipyridamole & cilostazol
Published	11/05/2024	therapeutic effects of dipyridamole & cilostazol
Published	11/05/2024	dipyridamole is a {{c1::weak antiplatelet}} so it can be combined with {{c2::warfarin}} or {{c2::aspirin}}
Published	11/05/2024	why is (dipyridamole + warfarin) preferred over (aspirin + warfarin)
Published	11/05/2024	side effects of epoprostenol
Published	11/05/2024	side effects of dipyridamole
Published	11/05/2024	dipyridamole is contraindicated in {{c1::coronary ischemia}}
Published	11/05/2024	explain the steal phonemena in dipyridamole
Published	11/05/2024	antiplatelets that act on ADP recpetor
Published	11/05/2024	mode of delivery of antiplatelets that act on ADP receptors
Published	11/05/2024	antiplatelets that act on fibrinogen receptor
Published	11/05/2024	chemical composition of abciximab
Published	11/05/2024	mode of delivery of antiplatelet acting on fibrinogen receptor
Published	11/05/2024	antiplatelets that act on fibrinogen recpetor are {{c1::reversible}} (reversible/irreversible) inhibitors
Published	11/05/2024	arterial thrombosis is usually treated with {{c1::antiplatelets}} (antiplatelets/anticoagulants)
Published	11/05/2024	therapeutic uses of antiplatelet drugs
Published	11/05/2024	{{c1::antiplatelets}} may be given in atrial fibrillation if anti-coagulants are CI
Published	11/05/2024	side effects of ticlopidine
Published	11/05/2024	side effects of clopidogrel
Published	11/05/2024	{{c1::omeprazole}} inhibits activation of clopidogrel (a prodrug) in the liver
Published	11/05/2024	side effects of prasugrel
Published	11/05/2024	prasugrel is contraindicated in patients with {{c1::history of TIA or stroke}}
Published	11/05/2024	side effects of ticagrelor
Published	11/05/2024	side effects of abciximab
Published	11/05/2024	side effects of cilostazol
Published	11/05/2024	cilostazol is contraindicated in {{c1::congestive heart failure}}
Published	11/05/2024	mode of delivery of ticlopidine
Published	11/05/2024	mode of delivery of clopidogrel
Published	11/05/2024	why is clopidogrel preferred over ticlopidine
Published	11/05/2024	mode of delivery of prasugrel
Published	11/05/2024	mode of delivery of cilostazol
Published	11/05/2024	duration of action of heparin
Published	11/05/2024	site of metabolism/excretion of heparin
Published	11/05/2024	why can't heparin pass into placenta or be secreted in milk
Published	11/05/2024	route of administration of heparin
Published	11/05/2024	why isn't heparin given by IM injection
Published	11/05/2024	how is heparin therapy controlled
Published	11/05/2024	heparin adverse effects
Published	11/05/2024	treatment of hemorrhage induced by heparin
Published	11/05/2024	potassium levels is monitored for if heparin is given for more than {{c1::7}} days
Published	11/05/2024	osteoporosis by heparin is more common {{c1::on long term use}} and {{c1::pregnancy}}
Published	11/05/2024	cause of heparin thrombocytopenia
Published	11/05/2024	management of heparin induced thrombocytopenia
Published	11/05/2024	examples of low molecular weight heparins (LMWHs)
Published	11/05/2024	mechanism of action of low molecular weight heparins (LMWHs)
Published	11/05/2024	route of administration of low molecular weight heparins (LMWHs)
Published	11/05/2024	advantages of low molecular weight heparins (LMWHs)
Published	11/05/2024	effect of protamine sulfate on indirect thrombin inhibitors & indirect selective inhibitors of factor Xa
Published	11/05/2024	chemical structure of indirect selective inhibitors of factor Xa
Published	11/05/2024	mechanism of indirect selective inhibitors of factor Xa
Published	11/05/2024	advantages of indirect selective inhibitors of factor Xa (fondaparinux)
Published	11/05/2024	uses of fondaparinux
Published	11/05/2024	route of administration of fondaparinux
Published	11/05/2024	major side effect of fondaparinux
Published	11/05/2024	why fondaparinux requires less monitoring than heparin
Published	11/05/2024	each mg of protamine sulfate neutralizes {{c1::100IU}} of heparin
Published	11/05/2024	why avoid overdose of protamine sulfate
Published	11/05/2024	examples of parenteral direct thrombin inhibitors
Published	11/05/2024	mechanism of action of parenteral direct thrombin inhibitors
Published	11/05/2024	route of administration of parenteral direct thrombin inhibitors
Published	11/05/2024	major side effect of parenteral direct thrombin inhibitors
Published	11/05/2024	uses of argatroban
Published	11/05/2024	uses of bivalirudin
Published	11/05/2024	{{c1::bivalirudin}} (parenteral direct thrombin inhibitor) inhibits platelet activation
Published	11/05/2024	mechanism of action of warfarin
Published	11/05/2024	effect of enzyme inhibition by warfarin
Published	11/05/2024	degree of absorption of warfarin
Published	11/05/2024	{{c1::99}}% of warfarin is bound to plasma proteins
Published	11/05/2024	metabolism & excretion of warfarin
Published	11/05/2024	does warfarin pass the placenta
Published	11/05/2024	can warfarin be given in lactation
Published	11/05/2024	why does warfarin have delayed onset
Published	11/05/2024	duration of action of warfarin {{c1::up to 6 days (long duration)}}
Published	11/05/2024	how to control warfarin therapy
Published	11/05/2024	normal PT
Published	11/05/2024	antidotes for warfarin
Published	11/05/2024	adverse effects of warfarin
Published	11/05/2024	disadvantages of warfarin
Published	11/05/2024	time for onset of action of warfarin
Published	11/05/2024	why does warfarin require overlapping therapy with heparin
Published	11/05/2024	Drugs that increase effect of warfarin (effect at level of GIT)
Published	11/05/2024	Drugs that increase effect of warfarin (effect at level of blood)
Published	11/05/2024	Drugs that increase effect of warfarin (effect at level of liver)
Published	11/05/2024	enzyme inhibitors of warfarin metabolism
Published	11/05/2024	Drugs that decrease effect of warfarin (effect at level of GIT)
Published	11/05/2024	Drugs that decrease effect of warfarin (effect at level of Blood)
Published	11/05/2024	Things that decrease effect of warfarin (effect at level of Liver)
Published	11/05/2024	enzyme inducers for warfarin
Published	11/05/2024	examples of newer oral anticoagulants (NOAC)
Published	11/05/2024	advantages of newer oral anticoagulants (NOAC) over warfarin
Published	11/05/2024	mechanism of action of rivaroxaban
Published	11/05/2024	mechanism of action of dabigatran
Published	11/05/2024	onset time of rivaroxaban and dabigatran
Published	11/05/2024	duration time of rivaroxaban
Published	11/05/2024	duration time of dabigatran
Published	11/05/2024	antidote for rivaroxaban
Published	11/05/2024	suspend
Published	11/05/2024	is warfrin used in renal impairment
Published	11/05/2024	is rivaroxaban used in renal impairment
Published	11/05/2024	is dabitgatran used in renal impairment
Published	11/05/2024	are rivaroxaban and dabigatran used in pregnancy?
Published	11/05/2024	oral anticoagulants used in thromboembolic propylaxis in AF
Published	11/05/2024	{{c1::apixaban}} and {{c1::edoxaban}} are drugs similar to rivaroxaban with {{c2::less risk of bleeding}} (advantage)
Published	11/05/2024	{{c1::dabigatran}} (oral anticoagulant) is a prodrug
Published	11/05/2024	absorption of dabigatran depends on {{c1::acid environment }}
Published	11/05/2024	{{c1::proton pump inhibitors}} decrease absorption of dabigatran
Published	11/05/2024	food increase bioavailability of {{c1::rivaroxaban}} (oral anticoagulant)
Published	11/05/2024	{{c1::dabigatran}} (oral anticoagulant) has low bioavailability
Published	11/05/2024	route of administration of fibrinolytics (thrombolytics)
Published	11/05/2024	mechanism action of fibrinolytics (thrombolytics)
Published	11/05/2024	plasmin digests fibrin and what else? (with pharmaceutical importance)
Published	11/05/2024	cause of risk of bleeding due to high plasmin in blood
Published	11/05/2024	the ideal fibrinolytic
Published	11/05/2024	indications of fibrinolytics
Published	11/05/2024	classification of fibrinolytics
Published	11/05/2024	first generation of fibrinolytics
Published	11/05/2024	second generation of fibrinolytics
Published	11/05/2024	parentral direct thrombin inhibitors inhibit {{c1::fibrin bound}} thrombin more than normal
Published	11/05/2024	vasodilator effect of heparin leads to {{c1::canalization}} of thrombus
Published	11/05/2024	phosphodiesterase inhibitors that increase cAMP in platelets
Published	11/05/2024	methods to reverse the effect of ANY NOAC (new oral anticoauglants)
Published	11/05/2024	methods to reverse the effect of Rivaroxaban NOAC (new oral anticoauglants)
Published	11/05/2024	methods to reverse the effect of dabigatran NOAC (new oral anticoauglants)
Published	11/05/2024	andexanet alfa is chemically formed of {{c1::recombinant factor Xa}}
Published	11/05/2024	Functions of andexanet alfa
Published	11/05/2024	Indications for anticoagulants
Published	11/05/2024	contrindications for anticoagulants
Published	11/05/2024	causes of increased risk of bleeding leading to contrindications for anticoagulants
Published	11/05/2024	treatment protocol for DVT
Published	11/05/2024	advantage of streptokinase fibrinolytic
Published	11/05/2024	advantage of urokinase fibrinolytic
Published	11/05/2024	mechanism of action of streptokinase
Published	11/05/2024	mechanism of action of urokinase
Published	11/05/2024	Disadvantages of first generation fibrinolytics
Published	11/05/2024	Advantages of second generation fibrinolytics
Published	11/05/2024	adverse effects of fibrinolytics
Published	11/05/2024	how to treat bleeding from fibrinolytics
Published	11/05/2024	how to deal with antigenicity when taking streptokinase
Published	11/05/2024	contraindications of fibrinolytics
Published	11/05/2024	why are anti-coagulants/anti-platelets given following fibrinolytic therapy
Published	11/05/2024	Drugs used in bleeding disorders
Published	11/05/2024	types of vitamin K
Published	11/05/2024	route of delivery of Vitamin K1
Published	11/05/2024	Indications of Vitamin K
Published	11/05/2024	adverse effects of Vitamin K
Published	11/05/2024	Types of Fibrinolytic inhibitors (antiplasmin)
Published	11/05/2024	mechanism of action of Aminocaproic acid
Published	11/05/2024	Uses of Aminocaproic acid
Published	11/05/2024	tissue rich in plasminogen activators
Published	11/05/2024	adverse effects of aminocaproic acid
Published	11/05/2024	advantages of tranexamic acid
Published	11/05/2024	define cryoprecipitate
Published	11/05/2024	mechanism of desmopressin
Published	11/05/2024	use of desmopressin
Status	Last Update	Fields