Notes in Clinical pharmacology

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Status	Last Update	Fields
Published	11/10/2024	Define pharmacodynamics?
Published	11/10/2024	Define pharmacokinetics
Published	11/10/2024	What are the 4 processes involved in pharmacokinetics?
Published	11/10/2024	Define clinical pharmacology
Published	11/10/2024	What must we consider when choosing a drug?
Published	11/10/2024	What molecules can drugs target inside the body and give an example of a drug for each?
Published	11/10/2024	Describe an agonist dose response curve
Published	11/10/2024	How does a partial agonist's dose response curve differ to a full agonist's
Published	11/10/2024	Define potency
Published	11/10/2024	Define ED50
Published	11/10/2024	Define efficacy
Published	11/10/2024	Define specificity of a drug
Published	11/10/2024	Define selectivity of a drug
Published	11/10/2024	Define theraputive index of a drug
Published	11/10/2024	Define a competitive antagonist
Published	11/10/2024	Define non-competitive antagonists
Published	11/10/2024	Describe the dose response curve of an antagonist
Published	11/10/2024	How do drugs act on enzymes?
Published	11/10/2024	Define tachyphylaxis
Published	11/10/2024	What can cause tachyphylaxis?
Published	11/10/2024	Define dose
Published	11/10/2024	What is a 1% w/v solution in mg/ml
Published	11/10/2024	How do we calculate drip rate?
Published	11/10/2024	If the dose for a species is unknown, how could we calculate the amount of a drug to administer?
Published	11/10/2024	What 4 factors determine the dosage regime of a drug?
Published	11/10/2024	What factors affect the dose of a drug?
Published	11/10/2024	What factors affect the onset of activity of a drug?
Published	11/10/2024	Define the loading dose of a drug
Published	11/10/2024	Define the maintenance dose of a drug
Published	11/10/2024	Describe saturation kinetics
Published	11/10/2024	What are the main plasma binding proteins for acidic drugs and basic drugs?
Published	11/10/2024	What factors affect the absorption of a drug?
Published	11/10/2024	What factors affect the distribution of a drug?
Published	11/10/2024	What factors affect the clearance/metabolism of a drug?
Published	11/10/2024	What factors affect the excretion of a drug?
Published	11/10/2024	How does ADME change for neonate and paediatric patients?
Published	11/10/2024	How does ADME change for geriatric patients?
Published	11/10/2024	Define the onset of action time of a drug?
Published	11/10/2024	Define the Tmax of a drug
Published	11/10/2024	Define the Cmax of a drug
Published	11/10/2024	Define the therapeutic window of a drug
Published	11/10/2024	Define drug elimation rate
Published	11/10/2024	Describe the process of drug metabolism
Published	11/10/2024	Define drug clearance
Published	11/10/2024	Define bioavailabilty (F) of a drug
Published	11/10/2024	Define the volume of distribution of a drug
Published	11/10/2024	Define the half life of a drug
Published	11/10/2024	What are the three types of enhanced effects of drug-drug interactions
Published	11/10/2024	How can drugs interact with each other physically and chemically?
Published	11/10/2024	What are the different mechanisms of drug-drug interactions in ADME?
Published	11/10/2024	Define additive drug-drug interactions
Published	11/10/2024	Define synergistic drug-drug interactions
Published	11/10/2024	Deine negation drug-drug interaction
Published	11/10/2024	Define an adverse event to a drug
Published	11/10/2024	What are the different types of adverse events in response to drugs?
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