Notes in Antimicrobials

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Status	Last Update	Fields
Published	11/10/2024	Define antimicrobial stewardship
Published	11/10/2024	What is the BVA's 7 point plan for responsible use of antibiotics?
Published	11/10/2024	Derfine primary/1st line use/prudent antibiotics and give some examples
Published	11/10/2024	Define secondary/2nd line use/cautious antbiotics and give some examples
Published	11/10/2024	Define tertiary/3rd line use/restricted antibiotics and give some examples
Published	11/10/2024	Define restricted/voluntary prohibition/avoid antibiotics and give an example
Published	11/10/2024	What is a CIA?
Published	11/10/2024	Define Antibiotic
Published	11/10/2024	What does the term "Magic bullet" mean?
Published	11/10/2024	What are common adverse reactions to antibiotics?
Published	11/10/2024	Describe narrow sepctrum antibiotics
Published	11/10/2024	Describr broad spectrum antibiotics
Published	11/10/2024	Describe the difference between bacteriocidal and bacteriostatic antibiotics
Published	11/10/2024	How do bacteriostatic antibiotics remove bacteria from the host?
Published	11/10/2024	Define MIC
Published	11/10/2024	Define MBC
Published	11/10/2024	What is the main target of cell wall targeting antibiotics?
Published	11/10/2024	What is the mechanism of action for beta lactam antibiotics?
Published	11/10/2024	What are the two classes of beta lactams?
Published	11/10/2024	Why is resistance to penicillins common?
Published	11/10/2024	Give 4 examples of penicillins
Published	11/10/2024	Why is amoxycillin combined with clavulanic acid in Amoxy/Clav?
Published	11/10/2024	How does methicillin differ to other penicillins?
Published	11/10/2024	Describe the different cephalosporin generations (1-5)
Published	11/10/2024	Describe the mechanism of action of peptide antibiotics
Published	11/10/2024	What are the two classes of peptide antibiotics?
Published	11/10/2024	Describe the mechanism of action of ribosome targeting enzymes
Published	11/10/2024	Why are ribosome targeting antibiotics always selective (magic bullet)?
Published	11/10/2024	How is resistance to ribosome taregting antibiotics generated?
Published	11/10/2024	Which 4 classes of antibiotics are ribosome targeting?
Published	11/10/2024	What is the spectrum of activity of aminoglycosides?
Published	11/10/2024	What is the spectrum of activity of tetracyclines?
Published	11/10/2024	What is the spectrum of activity of chloramphenicol?
Published	11/10/2024	What is the spectrum of activity of macrolides?
Published	11/10/2024	Describe the mechanism of action of TMPS
Published	11/10/2024	Describe the mechanism of action of quinolones
Published	11/10/2024	Describe the mechanism of action of nitroimidazoles
Published	11/10/2024	Describe the mechanism of action of rifampicin
Published	11/10/2024	Describe the use of cationic antimicrobial peptides
Published	11/10/2024	Which antibiotic classes rely on anaerobic/aerobic conditions to function?
Published	11/10/2024	How do we measure antibiotic resistance?
Published	11/10/2024	How is disk diffusion used for antibiotic resistance determination?
Published	11/10/2024	How do breakpoints work for AMR determination?
Published	11/10/2024	What is the difference between intrinsic and acquired AMR?
Published	11/10/2024	Define MDR
Published	11/10/2024	Define XDR
Published	11/10/2024	Define PDR
Published	11/10/2024	Why do we combien antimicrobials?
Published	11/10/2024	Give two examples of common antibiotic synergies?
Published	11/10/2024	Give 2 examples of antagonistic relationships between antibiotics
Published	11/10/2024	Give an example of two antibiotics that are used together empirically to cover a wide range of bacteria
Status	Last Update	Fields