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Chapter_22:_Thyroid
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six-kansas-green-mirror-angel-island
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Published
07/07/2024
The embryologic origin of the thyroid is the {{c2::1st}} and {{c2::2nd}} pharyngeal {{c1::arches}}
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The first branch off the external carotid artery is the {{c1::superior thyroid}} artery
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The inferior thyroid artery branches off the {{c1::thyrocervical trunk}}
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1% of patients have a(n) {{c1::thyroid ima}} artery, which goes to the isthmus of the thyroid
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The {{c2::superior}} and {{c2::middle}} thyroid veins drain into the {{c1::internal jugular}} vein
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The {{c2::inferior}} thyroid vein drains into the {{c1::innominate}} vein
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The superior laryngeal nerve supplies motor innervation to the {{c1::cricothyroid}} muscle
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The superior laryngeal nerve runs {{c1::lateral}} to the thyroid lobes
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The recurrent laryngeal nerve runs {{c1::posterior}} to the thyroid lobes in the {{c2::tracheoesophageal groove}}
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The most commonly injured nerve during a thyroidectomy is the {{c1::superior laryngeal}} nerve
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Injury to the superior laryngeal nerve results in loss of {{c1::high pitched voice}} and easy voice fatigability
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The left recurrent laryngeal nerve loops around the {{c1::aorta}}
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The right recurrent laryngeal nerve loops around the {{c1::innominate artery}}
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Unilateral injury to the recurrent laryngeal nerve results in {{c1::hoarseness}}
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Bilateral injury to the recurrent laryngeal nerve results in {{c1::airway obstruction}}
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The presence of a non-recurrent laryngeal nerve is more common on the {{c1::right}} side
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The thyroid is connected to the trachea via the ligament of {{c1::Berry}}
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The ligament of Berry is also known as the {{c1::suspensory}} ligament of the thyroid
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The thyroid protein that stores T3 and T4 in colloid is {{c1::thyroglobulin}}
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The normal plasma T4:T3 ratio is {{c1::15}} to {{c1::1}}
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The liver protein that binds the majority of T3 and T4 in circulation is {{c1::thyroxine-binding globulin (TBG…
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Projections of normal thyroid tissue from the posteromedial margin of the thyroid gland are known as {{c1::tubercles of Zuckerkandl}}
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Stridor after thyroidectomy due to bleeding is treated with {{c1::surgical removal of the hematoma}}
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Thyroid storm is most common after surgery in a patient with undiagnosed {{c1::Graves' disease}}
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The first drug to give during thyroid storm is {{c1::beta blockers}}
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Iodine administration treats thyroid storm due to the {{c1::Wolff-Chaikoff}} effect
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Most (90%) of thyroid nodules are {{c1::benign}}(benign or malignant)
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The best initial test for an asymptomatic thyroid nodule is {{c1::fine needle aspiration (FNA)}}
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A thyroid nodule that shows follicular cells on FNA is treated with {{c1::lobectomy}}
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A thyroid nodule that shows cyst fluid on FNA is treated with {{c1::drainage}}
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Cystic fluid from a thyroid nodule on FNA that recurs or is bloody is treated with {{c1::lobectomy}}
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A thyroid nodule that shows colloid tissue on FNA has a {{c1::low}} chance of being malignant(low or high)
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The treatment for a thyroid nodule that shows colloid tissue on FNA is {{c1::thyroxine}}
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A thyroid nodule that has normal thyroid tissue on FNA but with elevated thyroid function tests is likely a(n) {{c1::solitary toxic nodule}}
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A thyroid nodule that has an indeterminant FNA is followed up with a(n) {{c1::radionuclide}} study
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A thyroid nodule is treated with lobectomy if it is {{c1::cold}} on a radionuclide study(hot or cold)
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Any abnormal enlargement of the thyroid is known as a(n) {{c1::goiter}}
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The most common identifiable cause of a thyroid goiter is {{c1::iodine deficiency}}
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Diffuse enlargement of the thyroid without evidence of functional abnormality is known as a(n) {{c1::nontoxic}} goiter
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Diffuse enlargement of the thyroid with evidence of hyperfunctionality is known as a(n) {{c1::toxic}} goiter
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Nontoxic thyroid goiters are typically treated with {{c1::thyroxine}}
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Goiters that extend into the thoracic cavity are known as {{c1::substernal}} goiters
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A substernal goiter that arises from ectopic thyroid tissue in the mediastinum is known as a {{c1::primary}} substernal goiter(primary or secondary)
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A substernal goiter that descends from the neck and passes below the thoracic inlet is known as a {{c1::secondary}} substerna…
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Primary substernal goiters are {{c1::less}} common than secondary substernal goiters(more or less)
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10% of patients have a(n) {{c1::pyramidal}} lobe of the thyroid, which extends towards the thymus
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A lingual thyroid is thyroid tissue that persists in the {{c1::foramen cecum}} at the base of the tongue
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Thyroglossal duct cysts present as midline cervical masses between the {{c2::hyoid bone}} and the {{c1::thyroid isthmus}}
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The first line drug for hyperthyroidism is {{c1::methimazole}}
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Patients with hyperthyroidism who are poor surgical candidates or unresponsive to methimazole are treated with {{c1::131I}}
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Pregnant patients with hyperthyroidism can be treated with surgical resection during the {{c1::2nd}} trimester
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The most common cause of hyperthyroidism is {{c1::Graves' disease}}
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Symptoms specific to Graves' disease are {{c2::exophthalmos}} and {{c1::pretibial edema}}
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Graves' disease is caused by IgG antibodies against the {{c1::TSH receptor}}
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95% of the time, Graves' disease is successfully treated with {{c1::medical therapy}}
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The most common indication for surgery in Graves' disease is {{c1::presence of suspicious nodule}}
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The drugs given to a patient prior to surgery for Graves' disease are {{c3::methimazole}}, {{c2::beta-blocker}}, and {{c1::Lugol's solution}}
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The preferred initial treatment for a toxic multinodular goiter is usually {{c1::surgery}}
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The preferred initial treatment for a single toxic thyroid nodule is usually {{c1::medical therapy}}
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The most common cause of hypothyroidism in adults is {{c1::Hashimoto's thyroiditis}}
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Hashimoto's thyroiditis causes a goiter due to {{c1::trapped iodide}} inside the thyroid
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The first line treatment for Hashimoto's thyroiditis is {{c1::thyroxine}}
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Bacterial thyroiditis is usually secondary to {{c2::contiguous}} spread and is treated with {{c1::antibiotics}}
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Inflammation of the thyroid that is associated with elevated ESR and a tender thyroid is {{c1::De Quervain's}} thyroiditis
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The treatment for De Quervain's thyroiditis is {{c2::steroids}} and {{c1::aspirin}}
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Extensive fibrosis and inflammatory infiltration of the thyroid that extends into adjacent tissues is {{c1::Riedel's}} thyroiditis
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The medical treatment for Riedel's thyroiditis is {{c2::steroids}} and {{c1::thyroxine}}
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Symptoms of airway compromise in Riedel's thyroiditis are treated surgically with tracheostomy or {{c1::isthmectomy}}
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The most common endocrine malignancy in the US is {{c1::thyroid}} cancer
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The most common thyroid cancer is {{c1::papillary thyroid}} carcinoma
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Childhood radiation therapy to the neck is an important risk factor for {{c1::papillary}} thyroid carcinoma
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Metastases from papillary thyroid carcinoma (rare) usually go to the {{c1::lung}}
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Papillary thyroid carcinoma in children is {{c1::more}} likely to be node positive than in adults(more or less)
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Pathology for papillary thyroid carcinoma shows {{c2::psammoma}} bodies and {{c1::Orphan Annie}} nuclei
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Papillary thyroid carcinoma is a type of thyroid cancer with the {{c1::best}} prognosis(best or worst)
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Follicular thyroid carcinoma, when metastatic, spreads {{c1::hematogenously}}
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The most common location of metastasis for follicular thyroid carcinoma is {{c1::bone}}
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Indications for a total thyroidectomy for papillary or follicular thyroid carcinoma are size > {{c2::1}} cm or previous {{c1::XRT}}
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An indication for modified radical neck dissection (MRND) for papillary or follicular thyroid carcinoma is {{c1::extra-thyroidal disease}}
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Post-op 131I treatment for papillary and follicular thyroid cancer is indicated for tumor size > {{c2::1}} cm and {{c1::extra-thyroidal}}…
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Post-op 131I treatment for papillary and follicular thyroid cancer is only effective after {{c1::total thyroidectomy}}
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Papillary thyroid carcinoma that has spread to neck lymph nodes is treated with total thyroidectomy, {{c1::MRND}}, and 131I
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Risk factors for thyroid carcinoma recurrence or metastases can be remembered with X-GAMES{{c1::Previous XRT}}{{c2::High Grade}}{{c3::Age (<20 or &…
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Medullary thyroid carcinoma from MEN 2 syndromes is {{c1::less}} common than from sporadic cases
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The first manifestation of MEN 2a and 2b syndromes is usually {{c1::medullary thyroid carcinoma}}, which presents with {{c2::diarrhea}}
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Medullary thyroid carcinoma arises from {{c1::parafollicular C}} cells that secrete calcitonin
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Amyloid deposition can be seen in {{c1::medullary}} thyroid carcinoma
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Patients with medullary thyroid carcinoma need to be screened for {{c2::hyperparathyroidism}} and {{c1::pheochromocytoma}}
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Medullary thyroid carcinoma from MEN 2a has a {{c1::better}} prognosis than from MEN 2b(better or worse)
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Medullary thyroid carcinoma is treated with {{c2::total thyroidectomy}} with {{c1::central neck node dissection}}
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Prophylactic thyroidectomy and central node dissection are performed for MEN 2a at age {{c1::6}} year(s)
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Prophylactic thyroidectomy and central node dissection are performed for MEN 2b at age {{c1::2}} yea…
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Disease recurrence for medullary thyroid carcinoma can be monitored with serum {{c1::calcitonin}} levels
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Most cases of Hurthle cell abnormalities in the thyroid are {{c1::benign}}(benign or malignant)
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Pathology of Hurthle cell carcinoma shows {{c1::Ashkenazi}} cells
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Hurthle cell carcinoma is typically treated with {{c1::lobectomy}}
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Anaplastic thyroid carcinoma is a type of thyroid cancer with the {{c1::worst}} prognosis(best or worst)
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Anaplastic thyroid carcinoma is usually treated with {{c1::palliative care}}
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Which type(s) of thyroid carcinomas does XRT effectively treat?{{c1::Papillary, Follicular, Medullary, and Hurthle}}
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Which type(s) of thyroid carcinomas does 131I effectively treat?{{c1::Papillary and Follicular}}
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Is 131I treatment safe for breast feeding?{{c1::No}}
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Thyroid replacement (thyroxine) can only be given {{c1::after}} 131I therapy(before or after)
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131I therapy is started {{c1::4}}-{{c1::6}} weeks after thyroidectomy
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In {{c2::80}}% of patients, the recurrent laryngeal nerve runs {{c3::pos}}terior and {{c3::medi}}al to the tubercle of {{c1::Zuckerkandl}}
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