Notes in Metabotropic Neurotransmitters Receptors and Postsynaptic Mechanisms

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Published	09/07/2023	metabotropic receptors require {{c1::metabolic steps}} within the cell to mediate the opening/closing of ion chanels
Published	09/07/2023	True or False: Metabotropic receptors and ion channel are separate molecules in the membrane
Published	09/07/2023	{{c1::G-protein couple receptors or GPCRs}} are a common example of metabrotropic receptors
Published	09/07/2023	GPCRs are {{c1::monomeric integral proteins}} that can be associated with either a {{c2::heterotrimeric}} G-protein or a {{c2::monomeric}} G-protein. …
Published	09/07/2023	{{c1::Ras}} is common example of a monomeric G-protein.
Published	09/07/2023	The signal produced by a neurotransmitter binding to a GPCR is {{c1::amplifed}} and {{c1::diversified}} by the triggering of effectors and secondary m…
Published	09/07/2023	Metabotropic receptors mediate {{c1::slower}} developing and more {{c1::persistent}} post synaptic effects than the ionotropic receptors
Published	09/07/2023	GPCRs can have long term affect on the cell by indirectly activating {{c1::transcription factors}}, like CREB.
Published	09/07/2023	Describe the GPCR structure (3 key points)
Published	09/07/2023	{{c1::muscarinic acetylcholine}} receptors are GPCRs that bind acetylcholine in the heart
Published	09/07/2023	An example of a metabotropic glutamate receptor is {{c1::mGluR}}
Published	09/07/2023	{{c1::β adrenergic}} receptors are a GPCR bound by norepinephrine
Published	09/07/2023	An example of a metabotropic dopamine receptor is {{c1::Dopamine D2}}
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