Notes in Cervical cancer

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Status	Last Update	Fields
Published	02/18/2024	FRS \| Cervix \| 1.4.1 \| HPV \| Describe the mechanism of HPV mediated loss of p53 and pRB function. How is p16 expression related to HPV-associated canc…
Published	02/18/2024	FRS \| Cervix \| 1.6.1 \| Natural history \| Precursor lesions
Published	02/18/2024	FRS \| Cervix \| 1.4 \| Aetiology
Published	02/18/2024	FRS \| Cervix \| 2.2 \| Pathology \| Invasive carcinoma \| List the types of invasive cancer of the cervix
Published	02/18/2024	FRS \| Cervix \| 2.2 \| Pathology \| SCC \| Subtypes \| List the subtypes of invasive cervix SCC
Published	02/18/2024	FRS \| Cervix \| 2.3.1.1 \| Pathology \| Adenocarcinoma \| Describe the clinicopathologic feaures of invasive adenocarcinoma of the cervix
Published	02/18/2024	FRS \| Cervix \| 2.3.2 \| Pathology \| Adenocarcinoma \| Subtypes \| List the subtypes of invasive adenocarcinoma
Published	02/18/2024	FRS \| Cervix \| 1.7 \| Clinical presentation
Published	02/18/2024	FRS \| Cervix \| 1.6.2 \| Natural history \| Patterns of spread
Published	02/18/2024	FRS \| Cervix \| 1.6.3 \| Natural history and prognosis \| Create a table to describe the risk of pelvic and PA LN involvement as well as the 5yr OS by FI…
Published	02/18/2024	FRS \| Cervix \| 3.3 \| Prognostic factors
Published	02/18/2024	FRS \| Cervix \| 4.1 \| Management overview \| Provide a brief overview of the stage-by-stage management of cervical cancer
Published	02/18/2024	FRS \| Cervix \| 6.1 \| Carcinoma in situ (or HGSIL) \| Provide a brief overview of the managent of HGSIL
Published	02/18/2024	FRS \| Cervix \| 6.2.1 \| Early microinvasive \| IA1 \| Approach
Published	02/18/2024	FRS \| Cervix \| 6.2.3.1 \| Early non-bulky (<=4cm) \| IB1, IB2, IIA1 \| Approach
Published	02/18/2024	FRS \| Cervix \| 6.2.2 \| Early microinvasive \| IA2 (or IA1 with LVSI) \| Approach
Published	02/18/2024	FRS \| Cervix \| 6.2.4 \| Early bulky (>4cm) \| IB3, IIA2 \| Approach
Published	02/18/2024	FRS \| Cervix \| 6.2.5.1 \| Early stage \| Adjuvant treatment after surgery \| Approach
Published	02/18/2024	FRS \| Cervix \| 6.3.1 \| Locally advanced \| IIB, III, IVA \| Approach
Published	02/18/2024	FRS \| Cervix \| 6.2.5.2 \| Early stage \| Adjuvant treatment after surgery \| Evidence \| Intermediate risk \| GOG 92 (Sedlis Gyn Onc 1999; Rotman IJROBP 20…
Published	02/18/2024	FRS \| Cervix \| 6.2.5.0.1 \| Early \| RT vs. Surgery \| Landoni trial (Milan), Lancet 1997 (1986-91)
Published	02/18/2024	FRS \| Cervix \| 6.2.5.3 \| Early stage \| Adjuvant treatment after surgery \| Evidence \| High risk \| GOG 109 Peters JCO 2000
Published	02/18/2024	FRS \| Cervix \| 6.4.1 \| Advanced \| IVB \| Approach
Published	02/18/2024	FRS \| Cervix \| 6.3.2.1 \| Locally advanced \| IIB, III, IVA \| Evidence \| Concurrent chemoRT
Published	02/18/2024	FRS \| Cervix \| 6.5.2 \| Special scenarios \| Role of anemia/hypoxia
Published	02/18/2024	FRS \| Cervix \| 6.5.1 \| Special scenarios \| Neoadjuvant chemotherapy prior to surgery
Published	02/18/2024	FRS \| Cervix \| 6.5.4 \| Special scenarios \| Urgent presentation with PV bleeding, low Hb (localised disease)
Published	02/18/2024	FRS \| Cervix \| 6.5.3 \| Special scenarios \| Role of surgery in LN positive disease
Published	02/18/2024	FRS \| Cervix \| 6.5.5 \| Special scenarios \| Perforation at first fraction of brachytherapy
Published	02/18/2024	FRS \| Cervix \| 6.5.6 \| Special scenarios \| Incidental diagnosis of cervicla cancer after simple hysterectomy
Published	02/18/2024	FRS \| Cervix \| 6.5.7 \| Special scenarios \| Cervical cancer in pregnancy
Published	02/18/2024	FRS \| Cervix \| 6.5.8 \| Special scenarios \| Small cell cervix cancer
Published	02/18/2024	FRS \| Cervix \| 6.3.2.2 \| Locally advanced \| IIB, III, IVA \| Evidence \| Adjuvant chemo (controversial)
Published	02/18/2024	FRS \| Cervix \| 5.4 \| Principles of Surgery \| Lymph node dissection
Published	02/18/2024	FRS \| Cervix \| 5.1 \| Principles of Surgery \| Excisional biopsy (Cone / LEEP/ LLETZ)
Published	02/18/2024	FRS \| Cervix \| 5.2 \| Principles of Surgery \| Fertility preserving surgery (trachelectomy)
Published	02/18/2024	FRS \| Cervix \| 5.3.1 \| Principles of Surgery \| Hysterectomy
Published	02/18/2024	FRS \| Cervix \| 6.2.5.0.2 \| Surgery vs. RT \| Discuss the advantages and disadvantages of surgery and radiotherapy for early (bulky or non-bulky) cervix…
Published	02/18/2024	FRS \| Cervix \| x.x \| GOG score
Published	02/18/2024	FRS \| Cervix \| 6.3.1.x \| Management - Locally advanced: Stage IIB, III and IVA
Published	02/18/2024	FRS \| Cervix \| 1.1 \| Anatomy
Published	02/18/2024	FRS \| Cervix \| 1.2 \| Epidemiology
Published	02/18/2024	FRS \| Cervix \| 1.3 \| Risk factors
Published	02/18/2024	FRS \| Cervix \| 1.5 \| HPV vaccine \| List the strains covered by the HPV vaccine, describe the schedule, funding and efficacy
Published	02/18/2024	FRS \| Cervix \| 1.8 \|  Workup
Published	02/18/2024	FRS \| Cervix \| 1.8 \| Screening
Published	02/18/2024	FRS \| Cervix \| 2.1.1 \| Pathology \| Pre-invasive lesions \| Squamous \| Describe the categories of pre-invasive squamous epithelial lesions (AMBS, 2004) …
Published	02/18/2024	FRS \| Cervix \| 2.1.2 \| Pathology \| Pre-invasive lesions \| Squamous \| Create a table to compare the various classification systems for squamous pre-inv…
Published	02/18/2024	FRS \| Cervix \| 2.1.3 \| Pathology \| Pre-invasive lesions \| Glandular \| Describe the categories of pre-invasive glandular epithelial lesions (AMBS, 2004…
Published	02/18/2024	FRS \| Cervix \| 2.4 \| Pathology \| Summary \| Create a table to summarise the epidemiology, risk factors, natural history, biological behaviour, pre…
Published	02/18/2024	FRS \| Cervix \| 2.5 \| Pathology report \| List the features to include on a pathology report for cervical cytology/ HPV test report or colposcopic speci…
Published	02/18/2024	FRS \| Cervix \| 2.6 \| Colpsocopy report
Published	02/18/2024	FRS \| Cervix \| 2.7 \| Pathology report \| Hysterectomy pathology report
Published	02/18/2024	FRS \| Cervix \| 3.1 \| Staging \| Outline the differences between 2009 and 2018 staging of cervical cancer
Published	02/18/2024	FRS \| Cervix \| 3.2 \| Staging \| Describe the FIGO 2018 staging system for cervical cancer
Published	02/18/2024	FRS \| Cervix \| 4.2 \| Follow up
Published	02/18/2024	FRS \| Cervix \| 4.3 \| Management at recurrence
Published	02/18/2024	FRS \| Cervix \| 5.3.2 \| Principles of surgery \| Hysterectomy and trachelectomy types \| Create a table to compare the three types of hysterectomy and tw…
Published	02/18/2024	FRS \| Cervix \| 5.3.3 \| Principes of surgery \| Exenteration \| Create a table to compare the types of pelvic exenteration for cervix cancer; including t…
Published	02/18/2024	FRS \| Cervix \| x.x \| Chemotherapy regimens (NCCN)
Published	02/18/2024	FRS \| Cervix \| 4.4 \| Prognosis \| 5yr OS by stage
Published	02/18/2024	FRS \| Cervix \| 6.6 \| Recurrent disease
Published	02/18/2024	FRS \| Cervix \| 7.1 \| RT technique \| Adjuvant RT
Published	02/18/2024	FRS \| Cervix \| 7.2 \| RT technique \| Definitive chemoradiotherapy
Published	02/18/2024	FRS \| Cervix \| 7.3 \| RT technique \| Brachytherapy
Published	02/18/2024	FRS \| Cervix \| 8.1 \| Brachytherapy \| Indications and contraindications
Published	02/18/2024	FRS \| Cervix \| 8.2 \| Brachytherapy \| Overview
Published	02/18/2024	FRS \| Cervix \| 8.3 \| Brachytherapy \| Assessing response to EBRT
Published	02/18/2024	FRS \| Cervix \| 8.4 \| Brachytherapy \| Applicators
Published	02/18/2024	FRS \| Cervix \| 8.6 \| Brachytherapy \| Procedure \| Describe the procedure for cervial intracavitatory brachytherapy (in particular inseriton of applicat…
Published	02/18/2024	FRS \| Cervix \| 8.5.1 \| Brachytherapy \| Planning and dose prescription
Published	02/18/2024	FRS \| Cervix \| 8.5.2 \| Brachytherapy \| Manchester system
Published	02/18/2024	FRS \| Cervix \| 8.7 \| Brachytherapy \| HDR vs. LDR
Published	02/18/2024	FRS \| Cervix \| 8.8 \| Brachytherapy \| RIsks
Published	02/18/2024	FRS \| Cervix \| 8.9 \| Brachytherapy \| Evidence
Published	02/18/2024	FRS \| Cervix \| 2.3.1.2 \| Pathology \| Adenocarcinoma \| Differentiation between cervix adenocarcinoma vs. cervical involvement by endometrial adeno…
Published	02/18/2024	FRS \| Cervix \| 8.5.3 \| Brachytherapy \| MRI guidance \| EMBRACE I trial
Published	02/18/2024	FRS \| Cervix \| 8.5.3 \| Brachytherapy \| MRI guidance \| EMBRACE II trial
Published	02/18/2024	Cervical cancer pathogenesis
Published	02/18/2024	FRS \| Cervix \| 6.3.3 \| Locally advanced \| Extended field RT
Status	Last Update	Fields