Notes in 01_Hepatitis

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Published 02/10/2024 Causes of Hepatitis {{c1::Alcoholic hepatitis}}{{c1::Non alcoholic fatty liver disease (NAFLD)}} {{c1::Viral hepatitis}} {{c1::Autoimmune hepatitis}} …
Published 02/10/2024 Presentation of {{c2::Hepatitis}} {{c1::Abdominal pain}} {{c1::Fatigue}} {{c1::Pruritis (itching)}} {{c1::Muscle and joint aches}}  {{c1::Nausea}…
Published 02/10/2024 Presentation of {{c2::Alcoholic hepatitis}}{{c1::Smelling of alcohol and Hx of alcohol}}{{c1::Jaundice}} {{c1::Encephalopathy}} {{c1::Infection}} {{c1…
Published 02/10/2024 Viral hepatitis is caused by five main types of viruses {{c1::A}}, {{c1::B}}, {{c1::C}}, {{c1::D}} and {{c1::E}}
Published 02/10/2024 Hepatitis {{c1::A}} and {{c1::E}} are {{c2::enteric}} viruses
Published 02/10/2024 Hepatitis {{c1::B}}, {{c1::C}} and {{c1::D}} are {{c2::parenteral}} viruses
Published 02/10/2024 Hepatitis {{c1::A}} and {{c1::E}} cause {{c2::self limiting}} and {{c2::acute}} infections
Published 02/10/2024 Hepatitis {{c1::B}}, {{c1::C}} and {{c1::D}} cause {{c2::chronic}} infections
Published 02/10/2024 Investigation of HAV involves assessing {{c1::Anti-HAV IgM}} in serum
Published 02/10/2024 Management of Hepatitis A{{c1::Vaccine for travellers to endemic areas}}  {{c1::Supportive therapy since it is self-resolving}} 
Published 02/10/2024 Hepatitis {{c1::B (HBV)}} is a DNA virus transmitted viaVertical transmission. Contaminated needles. Infected blood products. Sexual interco…
Published 02/10/2024 Markers of Hepatitis B (HBV) Investigation {{c1::Surface antigen (HBsAg)}} – active infection {{c1::E antigen (HBeAg)}} – marker of viral replica…
Published 02/10/2024 We can measure {{c1::IgM}} and {{c1::IgG}} versions of the Hep B core antibodies (HBcAb).
Published 02/10/2024 In HBV, {{c1::Hep B core antibodies (HBcAb)}} can help distinguish acute, chronic and past infections
Published 02/10/2024 {{c1::High}} titre of IgM with an {{c2::acute}} infection{{c1::Low}} titre of IgM with a {{c2::chronic}} infection
Published 02/10/2024 In HBV, presence of {{c1::IgG}} indicates a {{c2::past}} infection where the HBsAg is negative
Published 02/10/2024 Presence of {{c1::IgM}} implies an {{c2::active}} infection in Hepatits B
Published 02/10/2024 {{c2::Hepatitis B e antigen (HBeAg)}} implies that the patient is in an {{c1::acute}} phase of the Hep B infection where the virus is actively replica…
Published 02/10/2024 The level of {{c1::HBeAg}} correlates with the infectivity of a Hepatitis B patient
Published 02/10/2024 In HBV, If {{c2::HBeAg}} is {{c1::negative}} but the {{c2::HBeAb}} is {{c1::positive}} this implies that the patient has been through a phase whe…
Published 02/10/2024 Screening for Hepatitis BFirst: test {{c1::HBcAb}} for previous infection and {{c1::HBsAg}} for active infection. Second: If these are positive then d…
Published 02/10/2024 Major Complication of Hepatitis B {{c1::Liver Cirrhosis leading to end-stage liver disease (ESLD) or hepatocellular carcinoma}} 
Published 02/10/2024 Management of Hepatitis B{{c1::Oral antiviral drugs (to slow progression and reduce infectivity)}} {{c1::Pegylated interferon}}
Published 02/10/2024 Hepatitis {{c1::C}} is an RNA virus that causes inflammation of liver.
Published 02/10/2024 {{c1::Hepatitis C antibody}} is the screening test of HCV
Published 02/10/2024 {{c1::Hepatitis C RNA}} testing is used to confirm the diagnosis of HCV
Published 02/10/2024 Management of Hepatits C{{c1::Antiviral treatment withdirect acting antivirals (DAAs)}} 
Published 02/10/2024 Hepatitis {{c1::D}} is an RNA virus that can only survive in patients who also have a hepatitis B infection, by attaching itself to the HBsA…
Published 02/10/2024 Management of {{c2::Paracetamol overdose}} is via giving {{c1::n-acetylcysteine}} infusion
Published 02/10/2024 Autoimmune hepatitis is a rare cause of chronic hepatitis with two types:Type 1: occurs in {{c1::adults}}Type 2: occurs in {{c1::children}}
Published 02/10/2024 Features of Type 1 Autoimmune hepatitis  {{c1::Affects women in their late forties or fities}} {{c1::Presents with fatigue and enlarged liver}} {…
Published 02/10/2024 Features of Type 2 Autoimmune hepatitis {{c1::Patients in their teenage years or twenties}}{{c1::Presents with acute hepatitis and raised AL…
Published 02/10/2024 Treatment of Autoimmune hepatitis({{c1::High dose steroids e.g. prednisolone}})({{c1::Immunosuppressants e.g. azathioprine}})If End-sta…
Published 02/10/2024 Diagnosis of Alcoholic hepatitis {{c1::Alcohol history}} {{c1::Low albumin and raised prothrombin time/INR}}  {{c1::Raised ALP}}{{c1::R…
Published 02/10/2024 {{c1::Oral steroids (e.g. prednisolone)}} are given to treat severe alcohol hepatitis
Published 02/10/2024 {{c1::Thiamine}} is given to Alcoholic hepatitis patients to counteract {{c1::thiamine (B1)}} deficiency  which causes Wernicke–Korsakoff syndrom…
Published 02/10/2024 Scores to grade Alcoholic Hepatitis{{c1::Glasgow Alcoholic Hepatitis Score}}{{c1::Maddreys Discriminent Function Score}}
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