Notes in Week 6

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Published 10/29/2023 {{c1::B2 agonists}} work by activating {{c2::adenylyl cyclase}}, increase {{c3::cAMP}} production and causing smooth muscle {{c4::relaxation}}. It can…
Published 10/29/2023 Albuterol, metaproteronol, and tertbutaline are examples of {{c1::short acting B2 agonists (SABA)}}
Published 10/29/2023 Salmeterol and formoterol are examples of {{c1::long acting B2 agonists (LABA)}}
Published 11/07/2023 {{c2::Muscarinic antagonists::Medication}} for the lungs work by blocking {{c1::acetylcholine}}, resulting in {{c3::decreased}} smooth muscle contract…
Published 10/29/2023 Montelukast and zafirlukast are examples of {{c1::leukotriene receptor antagonists}}, which are mainly used for asthma {{c2::prophylaxis}}
Published 10/29/2023 Zileuton is an example of a {{c1::leukotriene synthesis inhibitor}}, which works by inhibiting {{c2::5-lipoxygenase}}. It is effective for asthma {{c3…
Published 10/29/2023 Theophylline is a {{c1::methylxanthine}}, which inhibits {{c2::phosphodiesterase (PDE)}}, increasing {{c3::cAMP}} within the cell, leading to smooth m…
Published 10/29/2023 Corticosteroids effect in mast cells:Increase {{c1::annexin-1}} proteins, which inhibits synthesis of {{c2::arachidonic acid}} (and therefore leukotri…
Published 10/31/2023 Corticosteroids effect in Th2 cells:Decrease {{c1::IL-4}} and {{c1::IL-5}} production, decreasing activity of {{c2::mast cells}} and {{c2::eosinophils…
Published 10/29/2023 Common suffix for corticosteroids is {{c1::-sone}} or {{c1::-lone}}
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