Notes in 15 Genetics

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1. Understanding Genetics
2. Genetic Syndromes

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Published	02/10/2024	Mendelian Inheritance is a {{c1::type of inheritance that occurs when the cause of a disease is a single abnormal gene on a non-sex chromosome (i.e. a…
Published	02/10/2024	Features of Autosomal {{c2::Dominant}} Inheritance {{c1::There are no carriers; if one has the single gene disease then they have the diseas…
Published	02/10/2024	Features of Autosomal {{c2::Recessive}} Inheritance {{c1::There are carriers; if one has the single gene disease.}} {{c1::It is possible to inherit an…
Published	02/10/2024	Examples of Autosomal Dominant Conditions {{c1::Tuberous sclerosis (TS)}} {{c1::Neurofibromatosis 1 (NF1)}} {{c1::Myotonic dystrophy}}
Published	02/10/2024	Examples of Autosomal Recessive Conditions{{c1::Cystic Fibrosis (CF)}}
Published	02/10/2024	Examples of X-Linked Conditions{{c1::Duchenne Muscular Dystrophy}}
Published	02/10/2024	Type of Gene Mutations that give rise to Cancer are {{c1::Germline}} Mutations which are heritable, and {{c1::Somatic}} Mutations which are nonhe…
Published	02/10/2024	In Familial cancer, the first mutation is {{c1::inherited}} and the second is {{c1::somatic}}
Published	02/10/2024	In Sporadic cancer, both mutations are {{c1::somatic i.e. not inherited}}
Published	02/10/2024	Three Stops/Processes of the Cell Cycle that play a role in Cancer Development [1] {{c1::Oncogenes (involved in cell growth)}}[2] {{c1:…
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