Notes in 07 Neuromuscular Blocking Agents

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Published 12/13/2023 When ACh binds both α subunits of the nicotinic receptor, {{c1::Na+}} and {{c1::Ca2+}} ions influx while {{c1::K+}} ions&nbsp…
Published 12/13/2023 The dose for succinylcholine is {{c1::1.5 - 2}} mg/kg if a defasciculating dose of rocuronium has already been given.
Published 12/13/2023 ESRD patients with a normal potassium level {{c1::is NOT::is/is not}} a contraindication for succinylcholine
Published 12/13/2023 Myalgia caused by succinylcholine is less frequent in {{c1::children::age group}} and those with good muscle training.
Published 12/13/2023 Myalgia caused by succinylcholine is more frequent in {{c1::women::gender}}.
Published 12/13/2023 Nondepolarizing paralytics cause {{c1::fade}} on train-of-four by blocking {{c2::pre}}synaptic nAChR.
Published 12/13/2023 The intubation dose of paralytics is typically {{c1::2-3}}x the {{c1::ED95}}.
Published 12/13/2023 Nondepolarizing NMBA ED95 = average dose to achieve {{c1::95}}% supression of twitch height in {{c1::50}}% of population.
Published 12/13/2023 Excretion of rocuronium occurs through {{c1::bile}} and {{c1::urine}}.
Published 12/13/2023 Most clinicians cannot distinguish a TOF ratio >{{c1::0.4}}
Published 12/13/2023 Full recovery from NMB is illustrated by TOF ratio = {{c1::0.9}}
Published 12/13/2023 Vecuronium's 3-OH active metabolite accumulates in {{c1::renal failure::disease state}}
Published 12/13/2023 When would you dose sugammadex at 16 mg/kg?{{c1::Deep blocks requiring immediate reversal (cannot intubate, cannot ventilate)}} 
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