Notes in 01_Vitamin B12 and Folate Deficiency Anaemia

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Published 02/10/2024 Presentation of {{c2::Macrocytic (B12/Folate Deficiency) Anaemia}}  {{c1::Usually asymptomatic (i.e. in megaloblastic)}} {{c1::Fatigue}} {{c…
Published 02/10/2024 Causes of Megaloblastic Anaemia are {{c1::Folate deficiency}}, {{c1::Vitamin B12 deficiency}}, and {{c1::Pernicious anaemia}}
Published 02/10/2024 Causes of Nonmegaloblastic Anaemia {{c1::Alcoholism}} {{c1::Hypothyroidism}} {{c1::Liver disease}} {{c1::Myelodysplastic syndromes}} {{c1::Drugs e.g. …
Published 02/10/2024 Causes of {{c2::Vitamin B12}} Deficiency{{c1::Malnutrition}}{{c1::Pernicious anaemia}}{{c1::Gastric/Ileal disease}}{{c1::Gastric Surgery}}
Published 02/10/2024 Causes of Folate Deficiency{{c1::Malnutrition}}{{c1::Increased Requirements due to Haemolysis}}{{c1::Coeliac Disease}}
Published 02/10/2024 Investigations of {{c2::Megaloblastic}} Anaemia {{c1::Full Blood Count and Blood Film:Low haemoglobinMacrocytic (MCV >100) and Hypersegmented Neutr…
Published 02/10/2024 Diagnosis of {{c2::Pernicious}} Anaemia is {{c1::Antibodies against Intrinsic Factor}}
Published 02/10/2024 Treatment of Megaloblastic Anaemia due to B12 Deficiency {{c1::B12 I/M injection if pernicious anaemia, if not then oral}} {{c1::Loading dose then 3 m…
Published 02/10/2024 Treatment of Megaloblastic Anaemia due to Folate Deficiency {{c1::Oral folate replacement (5mg daily for 4 months)}}
Published 02/10/2024 Why should you correct B12 levels first before correcting Folate levels if there are Neuropathic Symptoms?{{c1::Ensure that B12 levels are normal befo…
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