Notes in 17 Antimicrobials

To Subscribe, use this Key

Status	Last Update	Fields
Published	07/30/2024	All Protein Synthesis Inhibitors are ORAL except: {{c1::Tigecycline}} and {{c1::Streptogramin}}
Published	07/30/2024	Tetracyclines are the DOC for,{{c1::ChlamydiaPlague (Cholera, Tularemia)MalariaLeptospirosis Prophylaxis::4}}
Published	07/30/2024	{{c1::Minocyline::Antimicrobial}} reaches very high concentration in excretions such as tears, saliva, and breaskmilk, making it useful for eradicatio…
Published	07/30/2024	Can Tetracyclines be given to pregnant px?{{c1::N::Y/N}}
Published	07/30/2024	Tetracyclines are an alternative therapy for,{{c1::LeprosyCommunity-Acquired MRSA::2}}
Published	07/30/2024	Tetracycline ADEMost Common: Nausea, Vomiting, Diarrhea (GI)Teratogenic{{c1::Damage to teeth and bones (fluorescence, discoloration, and enamel dyspla…
Published	07/30/2024	Tetracyclines can alter the normal gastrointestinal flora and can cause Clostridium difficile-associated colitis.{{c1::TRUE::T/F}}
Published	07/30/2024	Tetracycline Contraindications:Pregnant px{{c1::children <8 y/o}}
Published	07/30/2024	Protein Synthesis Inhibitors: TETRACYLINEAdverse Effects{{c1::Renal tubular acidosis}} and {{c2::Fanconi syndrome}} have been attributed to the admini…
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDESDrug of Choice for {{c2::Mycoplasma}}, {{c2::Legionella}}, and {{c2::Chlamydial}} infections: {{c1::Erythromyc…
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDES - ErythromycinAdverse Effects: {{c1::Gastrointestinal Intolerance}}
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDES - ErythromycinErythromycin {{c1::inhibits::induces/inhibits}} CYP450 enzymes and is therefore associated with…
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDES{{c3::Erythromycin}} is the traditional drug of choice for {{c2::corynebacterial}} infections and respiratory,…
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDES{{c1::Erythromycin}} is recommended as prophylaxis against {{c2::endocarditis}} during dental procedures for p…
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDESQC: Half-life1) Erythromycin2) Clarithromycin{{c1::B}}
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDESQC: GI Intolerance1) Erythromycin2) Clarithromycin{{c1::A}}
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDESQC: Activity against Mycobacterium avium complex1) Erythromycin2) Clarithromycin{{c1::B}}
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDESQC: Activity against Staph and Strep1) Azithromycin2) Clarithromycin{{c1::B}}
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDESQC: Activity against H. influenzae1) Azithromycin2) Erythromycin{{c1::A}}
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDESQC: Coverage for atypical pathogens (Mycoplasma, Legionella, Chlamydia)1) Azithromycin2) Erythromycin{{c1::C}}
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDESQC: CYP450 inactivation1) Azithromycin2) Erythromycin{{c1::B}}
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDESQC: CYP450 inactivation1) Clarithromycin2) Erythromycin{{c1::C}}
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDESVR: 1) Aluminum and magnesium antacids2) Azithromycin bioavailability{{c1::C}}
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDESCommon cardiac adverse effect among macrolides: {{c1::Prolongation of QT interval}}
Published	07/30/2024	Protein Synthesis Inhibitors: LINCOSAMIDES{{c1::Clindamycin::Drug}} Coverage:Bacteriostatic against gram (+) aerobes ({{c2::strep, staph, pneumococci:…
Published	07/30/2024	Protein Synthesis Inhibitors: MACROLIDEST/FAzithromycin penetrates the CSF.{{c1::FALSE}}
Published	07/30/2024	Protein Synthesis Inhibitors: LINCOSAMIDEST/FClindamycin penetrates the CSF.{{c1::FALSE}}
Published	07/30/2024	Protein Synthesis Inhibitors: LINCOSAMIDES{{c1::Clindamycin::Drug}} Indications:{{c2::Anaerobic}} infection (outside CNS) (e.g., intraabdominal infect…
Published	07/30/2024	Protein Synthesis Inhibitors: LINCOSAMIDESAdverse EffectMost common: {{c1::Diarrhea, Nausea, Skin Rashes::3}}
Published	07/30/2024	Protein Synthesis Inhibitors: CHLORAMPHENICOLQC: Blood levels of chloramphenicol1) Oral Administration2) Parenteral Administration{{c1::A}}
Published	07/30/2024	Protein Synthesis Inhibitors: CHLORAMPHENICOLT/FChloramphenicol can penetrate CSF.{{c1::TRUE}}
Published	07/30/2024	Protein Synthesis Inhibitors: CHLORAMPHENICOLChloramphenicol is bacterio{{c1::static::static/cidal}} to:Aerobic and anerobic gram (+) and (-)Rick…
Published	07/30/2024	Protein Synthesis Inhibitors: CHLORAMPHENICOLChloramphenicol is bacterio{{c1::cidal::static/cidal}} to:H. influenzaeNeisseria meningitidisSome st…
Published	07/30/2024	Protein Synthesis Inhibitors: CHLORAMPHENICOLVR1) Chloramphenicol2) RBC production{{c1::B}}
Published	07/30/2024	Protein Synthesis Inhibitors: {{c1::CHLORAMPHENICOL}}Gray Baby Syndrome is associated with {{c1::Chloramphenicol::which antibiotic?}}
Published	07/30/2024	Protein Synthesis Inhibitors: OXAZOLIDINONESLinezolid bioavailbility (oral): {{c1::100%}}
Published	07/30/2024	Protein Synthesis Inhibitors: OXAZOLIDINONESQC: Linezolid1) CYP450 inducer2) CYP450 inhibitor{{c1::C}}
Published	07/30/2024	Protein Synthesis Inhibitors: OXAZOLIDINONESLinezolid Antimicrobial Activity:Gram ({{c1::+}}){{c2::Streptococci::Linezolid is primarily bacteriostatic…
Published	07/30/2024	Protein Synthesis Inhibitors: OXAZOLIDINONESLinezolid Indications:{{c1::Vancomycin::Drug}}-resistant E. faecium, nosocomia, pneumonia, and skin-infect…
Published	07/30/2024	Protein Synthesis Inhibitors: OXAZOLIDINONES - LinezolidMost common adverse effect: {{c1::Thrombocytopenia}}
Published	07/30/2024	Protein Synthesis Inhibitors: OXAZOLIDINONESLinezolid is also a {{c1::MAO inhibitor::its other MOA}}, hence there is a risk of severe hypertension if …
Published	07/30/2024	Protein Synthesis Inhibitors: OXAZOLIDINONES{{c1::Linezolid}} is also a MAO inhibitor, hence there is a risk of {{c2::severe hypertension}} if taken w…
Published	07/30/2024	Protein Synthesis Inhibitors: OXAZOLIDINONESCoadministration of linezolid with SSRI may lead to {{c1::Serotonin Syndrome}} (fever, agitation, mental s…
Published	07/30/2024	Protein Synthesis Inhibitors: {{c5::AMINOGLYCOSIDES::Drug Class}}{{c5::Aminoglycosides::Drug Class}} are used most widely Serious infections with…
Published	07/30/2024	Protein Synthesis Inhibitors: AMINOGLYCOSIDESMost associated adverse effect: {{c1::Ototoxicity}} and {{c1::Nephrotoxicity}}
Published	07/30/2024	f3fc26d71d284b748fe694fdbf233b4d-ao-1
Published	07/30/2024	f3fc26d71d284b748fe694fdbf233b4d-ao-2
Published	07/30/2024	f3fc26d71d284b748fe694fdbf233b4d-ao-3
Published	07/30/2024	f3fc26d71d284b748fe694fdbf233b4d-ao-4
Published	07/30/2024	f3fc26d71d284b748fe694fdbf233b4d-ao-5
Published	07/30/2024	Time-Dependent Killing Drugs{{c1::Clindamycin, Linezolid, All beta lactams, Macrolides, Tetracycline, Vancomycin}}
Published	07/30/2024	Concentration Dependent Killing Drugs{{c1::Streptogramins (Dalfopristin, Quinupristin), Aminoglycosides, Daptomycin, Metronidazole, Fluroquinolones, K…
Published	07/30/2024	Drug AbsorptionAll Penicillins must be taken without food except{{c1::AMOXICILLIN}}All Macrolides must be taken without food except{{c1::CLARITHROMYCI…
Published	07/30/2024	Elimination PathwaysAll Aminoglycosides - {{c1::renal}}All Penicillins - renal EXCEPT {{c2::Ampicillin, Oxacillin}} - {{c1::Renal & Biliary}}…
Published	07/30/2024	Penicillin DrugsChemistry & Basic Structureconsists of 2 rings: {{c1::1 beta-lactam ring1 thiazolide ring}}
Published	07/30/2024	Narrow Spectrum Penicillins Beta lactamase {{c1::sensitive}}{{c1::Penicillin G}}{{c1::Procaine Pen G}}{{c1::Benzathine Pen G}}{{c2::used in rheum…
Published	07/30/2024	Very Narrow Spectrum PenicillinsBeta lactamase {{c1::resistant}}Drugs:{{c1::Nafcillin, Oxacillin (IV), Cloxacillin (oral), Dicloxacillin}}Uses/Sp…
Published	07/30/2024	Broad Spectrum Penicillinsbeta lactamase {{c1::sensitive}}{{c3::Amoxicillin}}{{c1::oral}}side effects: {{c1::Diarrhea}}Indication: {{c1::Gra…
Published	07/30/2024	Extended Spectrum PenicillinsBeta lactamase {{c1::sensitive}}{{c1::Carboxy/Ureidopenicillins}}Use: {{c1::Pseudomonas, Enterobacteriaceae, Proteus}}
Published	07/30/2024	Extended Spectrum PenicillinsCarboxypeniocillins{{c1::Ticarcillin, Carbenicillin}}not active against {{c2::Enterococci}}
Published	07/30/2024	Extended Spectrum PenicillinsUreidopenicillins{{c2::Piperacillin}}has activity against {{c1::Enterococcus faecalis}}
Published	07/30/2024	Penicillin resistanceBeta lactam ring is hydrolyzed into {{c1::penicilloic acid}} (no antibacterial activity){{c1::Modification of target PB…
Published	07/30/2024	Penicillin dose for active inflammation of meninges i.e. bacterial menigits{{c1::Daily parenteral dose of 18-24 million units}}
Published	07/30/2024	Penicillin contraindicationsHypersensitivityAll penicillins share {{c1::cross allergenicity}}Bleeding abnormalitiescauses by {{c1::extended spect…
Published	07/30/2024	Penicillin adverse effectsFrequent: {{c1::Maculopapular rash}}after 72 hoursnot IgE mediatedOccasional:{{c2::Neutropenia}} - {{c1::Nafcillin…
Published	07/30/2024	Penicillin Drug Interactions{{c2::Carbenicillin or Ticarcillin }}{{c1::inactivate aminoglycosides }}{{c3::Ampicillin}}{{c1::decreased effect…
Published	07/30/2024	Beta Lactamase Inhibitors{{c1::Clavulanic Acid, Sulbactam, Tazobactam}}against {{c1::Staphylococci}}not good inhibitors of {{c1::Class C beta lac…
Published	07/30/2024	e01a7327e0ad4a7996211f5652222774-oa-1
Published	07/30/2024	e01a7327e0ad4a7996211f5652222774-oa-2
Published	07/30/2024	{{c1::Carbapenem::Antimicrobial}} Activity:G (-)G (+)P. aeruginosaAnaerobesEnterobacterEnterobactericeaeESBLpenicillin non-susceptible strains of pneu…
Published	07/30/2024	Carbapenems are {{c1::resistant::susceptible/resistant}} to most β lactamasesHowever, the following bacteria are still resistant{{c2::Enterococcus fae…
Published	07/30/2024	Carbapenems are all are cleared {{c1::renally}}, and the dose must be reduced in patients with {{c1::renal insufficiency}}
Published	07/30/2024	Out of all the carbapenems, {{c1::Ertapenem}} has the weakest Pseudomonas activity
Published	07/30/2024	CARBAPENEMS{{c1::Ertapenem::Drug}}Insufficiently active against P. aeruginosaIts spectrum of activity against Gram (+), Enterobacteriaceae, and anaero…
Published	07/30/2024	Out of all the carbapenems, {{c1::Ertapenem}} has the longest half-life (4 hours), and is given once a day
Published	07/30/2024	Carbapenem w/ Greater Gram (+) Activity{{c1::Imipenem}}
Published	07/30/2024	Carbapenem w/ Greater Gram (-) Activity{{c1::Doripenem, Meropenem}}
Published	07/30/2024	{{c1::Imipenem::Carbapenem}} is often combined w/ {{c2::cilastatin}} because is it degraded by renal dehydropeptidase
Published	07/30/2024	Can Carbapenems cross the BBB?{{c1::Y::Y/N}}
Published	07/30/2024	Out of all carbapenems, {{c1::imipenem}} has the highest frequency of causing {{c1::seizures::ADE}}
Published	07/30/2024	Patients allergic to penicillin are not allergic to carbapenems{{c1::False::T/F}}
Published	07/30/2024	{{c1::Vancomycin::Antimicrobial}} ActivityPoorly absorbed from the intestinal tract and is administered orally only for the treatment of {{c…
Published	07/30/2024	Can Vancomycin cross the BBB?{{c1::Y w/ inflammation::Y/N}}
Published	07/30/2024	For prosthetic device infections, CSF shunt infections, and catheter-related infections caused by MRSA to provide activity against coagulase-nega…
Published	07/30/2024	Vancomycin in combination with {{c1::cefotaxime or ceftriaxone::drug}} is recommended for treatment of meningitis suspected or known to be caused…
Published	07/30/2024	{{c1::Vancomycin::Drug}} ADE:{{c2::PhebitisNephrotoxicityOtotoxicity"Red Man Syndrome"::4}}
Published	07/30/2024	{{c1::Daptomycin::Antimicrobial}} ActivityVRSAUsed to treat skin or soft tissue infections and bacteremia/endocarditis
Published	07/30/2024	Daptomycin is contraindicated in px w/ {{c1::pneumonia}}
Published	07/30/2024	Daptomycin ADE{{c1::myopathyallergic pneumonitis::2}}
Published	07/30/2024	Vancomycin in combination with {{c1::gentamicin::drug}} is recommended as an alternative regimen for treatment of enterococci endocarditis in a patien…
Published	07/30/2024	Active against Gram (+) and (-) organisms and approved as a single 3-g dose for {{c2::uncomplicated UTI::disease}} in women, even pregnant women{{c1::…
Published	07/30/2024	{{c1::Bacitracin::Antimicrobial}} Activity:G ({{c2::+}}) microorganisms.Used by some neurosurgeons to irrigate meninges intraoperativelyCombined w/ po…
Published	07/30/2024	Bacitracin ADE{{c1::NephrotoxicHSR w/o CA::2}}
Published	07/30/2024	Bacitracin is administered {{c1::topically::ROA}} often w/ {{c1::polymyxin or neomycin::2}} to treat mixed flora of surface lesions
Published	07/30/2024	[QC] Treatment on UTI in pregnant px1. Cephalosporins2. Fosfomycin{{c1::A. Fosfomycin-resistant::Also give why}}*Both are safe to use
Published	07/30/2024	[QC] Eradicating SA Nasal Carriage1. Bacitracin2. Muciprocin{{c1::B}}
Published	07/30/2024	ANTIFOLATE DRUGS - SULFONAMIDESActivity against gram (+) and gram (-)? {{c1::Both are inhibited}}
Published	07/30/2024	{{c2::Sulfonamide::Antimicrobial}} Activity:G (+)G (-), enteric bacteria{{c1::Nocardia}}{{c1::Chlamydia trachomatis}}Some protozoaCommunity Acquired M…
Published	07/30/2024	Sulfonamides are bactericidal.{{c1::False. Sulfonamide alone is bacteriostatic and becomes bactericidal only when combined with a dihydrofolate reduct…
Published	07/30/2024	Sulfonamides have poor activity against {{c1::anaerobes}} and {{c1::pseudomonas}}
Published	07/30/2024	TMP-SFX is the DOC for,{{c1::P. jiroveci (formerly P.carinii) pneumonia in HIV/AIDS}}{{c1::Burkholderia cepacia}}{{c1::Stenotrophomonas maltophilia}}
Published	07/30/2024	{{c1::Sulfonamides}} - First line drug for Burkholderia cepacia and Stenotrophomonas maltophilia
Published	07/30/2024	Sulfonamides are an alternative drug for:{{c1::H. ducreyi}}{{c1::Bacillary (shigella) dysentery}}{{c1::Dermatitis herpetiformis}}{{c1::Plasmodium Falc…
Published	07/30/2024	Sulfonamide combinations that are second line drugs for Falciparum malaria:{{c1::Sulfadoxine pyrimethamine}}{{c1::Sulfalene pyrimethamine}}
Published	07/30/2024	Sulfonamide ADE:{{c1::Steven-Johnson Syndrome}}{{c1::Crystalluria}}{{c1::Nephrosis and nephritis}}{{c1::Hemolysis in px w/ G6PD Deficiency}}{{c1::Kern…
Published	07/30/2024	DNA gyrase inhibitors include what antimicrobial classes?{{c1::Fluoroquinolones}}{{c1::Nitroimidazoles}}
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONESFluoroquinolones were originally developed because of their excellent activity against gram-{{c1::negative::po…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONESMechanism of ActionQuinolones block bacterial DNA synthesis by inhibiting bacterial enzymes:{{c1::topoisomeras…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONES{{c1::Delafloxacin::Drug that}} has a uniquely balanced affinity for both topoisomerase II and topoisomerase I…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONES2nd Generation{{c1::Norfloxacin}} - least active of the fluoroquinolones against both gram-negative and gram-p…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONES2nd Generation{{c1::Ciprofloxacin, Enoxacin, Lomefloxacin, Levofloxacin, Ofloxacin and Perfloxacin::6 Drugs}}E…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONES2nd Generation{{c1::Ciprofloxacin}} - drug that is the most active agent of this group against gram-negative o…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONES2nd Generation{{c1::Levofloxacin}} - drug that has greater activity than Ciprofloxacin against gram-positive o…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONES3rd GenerationRespiratory fluoroquinolones include what three drugs?{{c1::Gemifloxacin, Levofloxacin, Moxiflox…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONES3rd Generation{{c1::Moxifloxacin}} - drug with modest activity against anaerobic bacteria BUT lacks appreciabl…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONES3rd Generation{{c1::Moxifloxacin}} - drug that is the most active fluoroquinolone against M. tuberculosis
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONES3rd Generation{{c1::Gatifloxacin}} - drug that is available only as an ophthalmic solution in the USA due to i…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONESClinical Uses{{c2::UTI}} except for {{c1::Moxifloxacin}}{{c2::Bacterial diarrhea}}Infections of {{c2::soft tis…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONESClinical Uses{{c1::Ciprofloxacin}} - Anthrax Treatment AND Prophylaxis{{c1::Levofloxacin}} - Anthrax prop…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONESClinical Uses: Chlamydial urethritis and cervicitisDrugs: {{c1::Levofloxacin, Ofloxacin::2}}
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONESClinical Uses: Second line for tuberculosis and non-tuberculous infectionsMeningococci EradicationProphyl…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONESClinical Uses: Gram-positive activityAtypical pneumonia agents (Chlamydia, Mycoplasma, Legionella)Drugs: …
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONESPharmacokineticsOral absorption is impaired by {{c1::divalent and trivalent cations}}, including {{c1::antacid…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONESAdverse effects:{{c1::Gatifloxacin}}, {{c1::Levofloxacin}}, {{c1::Gemifloxacin}} and {{c1::Moxifloxacin}} may …
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONESAdverse effects:{{c1::Gatifloxacin}} - been associated with hyperglycemia in diabetic patients and with hypogl…
Published	07/30/2024	DNA GYRASE INHIBITORS - FLUOROQUINOLONESOther Adverse effects:{{c1::Athropathy}}{{c1::Peipheral neuropathy}}NOT routinely recommended for patients und…
Published	07/30/2024	{{c1::Metronidazole}} is the DOC for,{{c2::Anaerobic infectionsPseudomembranous colitisTrichomonal vaginitisSymptomatic amebiasesGiardasis::5}}
Published	07/30/2024	Can Metronidazole cross the BBB?{{c1::Y::Y/N}}
Published	07/30/2024	Metronidazole is metabolized by the {{c1::liver}} and accumulation may result in {{c1::hepatic insufficiency}}
Published	07/30/2024	{{c1::Metronidazole}} - Drug of choice for:{{c2::Clostridium difficile}}{{c2::Trichomonal vaginitis}}{{c2::All symptomatic amebiasis}}
Published	07/30/2024	Metronidazole ADE:{{c1::Peripheral neuropathy}}{{c1::Disulfiram-like effect}}
Published	07/30/2024	{{c1::Ceftaroline}}5th gen cephalosporinhas some activity againstEnterococci
Published	07/30/2024	{{c1::1st Generation Cephalosporins (Cefazolin, Cefadroxil, Cephalexin, Cephalothin, Cephapirin, Cephradine)}}Alternative antistaphylococcal penicilli…
Published	07/30/2024	Proteus mirabilis are often sensitive to {{c1::first-generationcephalosporins.}}
Published	07/30/2024	{{c1::Cefazolin}}1st-generation cephalosporin that requires dose adjustments for impaired renal function
Published	07/30/2024	Route of administration for Cephalexin.{{c1::Oral}}
Published	07/30/2024	Route of administration for Cefazolin.{{c1::IV/IM}}
Published	07/30/2024	Excretion for Cefazolin and Cephalexin.{{c1::Renal}}
Published	07/30/2024	Coverage of Cefazolin and Cephalexin.{{c1::Streptococci and Staphylococci(methicillin-sensitive strains)Some Anaerobic cocci(NOT B.fragilis)}}
Published	07/30/2024	T/F: Cephalexin and cefazolin are indicated for meningitis.{{c1::F}}
Published	07/30/2024	Cephalexin or Cefazolin: Prophylaxis for recurrent UTI especially in children{{c1::Cephalexin}}
Published	07/30/2024	Cephalexin or Cefazolin: Surgical prophylaxis{{c1::Cefazolin}}
Published	07/30/2024	2nd Generation Cephalosporin Representative Drugs:{{c1::Cefaclor (PO), Cefuroxime (IV, PO), Cefoxitin (IV)}}
Published	07/30/2024	{{c1::Cefuroxime/Cefaclor::Cephalosporin}} Activity:{{c2::BL-producing H. influenzaeMoraxella}}
Published	07/30/2024	[QC] Activity against Serratia/ B. fragilis (renal)1. Cefuroxime/Cefaclor2. Cefoxitin{{c1::B}}
Published	07/30/2024	2nd Gen Cephalosporins have {{c1::poor::poor/great}} activity against Pseudomonas
Published	07/30/2024	Can 2nd Gen Cephalosporins cross the BBB?{{c1::Only Cefuroxime}}
Published	07/30/2024	Can Cefuroxime be used for meningitis?{{c1::N::Y/N}}
Published	07/30/2024	[QC] Mixed anaerobic infections & Surgical Prohylaxis1. Cefuroxime/Cefaclor2. Cefoxitin{{c1::B}}
Published	07/30/2024	Cefuroxime/Cefaclor or Cefoxitin: Can also be used as surgical prophylaxis due to anaerobic coverage{{c1::Cefoxitin}}
Published	07/30/2024	[QC] Easy to administer amongst children due to its good taste, leading to increased compliance1. Cefuroxime2. Cefaclor{{c1::B}}
Published	07/30/2024	Issue w/ Cefaclor?{{c1::For BL-producing H influenzae but it is itself, a BL-susceptible antimicrobial}}
Published	07/30/2024	3rd Generation cephalosporins that are able to cross the BBB.{{c1::Ceftriaxone, Cefotaxime}}
Published	07/30/2024	Generation of cephalosporins that are:Effective against Haemophilus and Neisseria, useful inrespiratory and genitourinary infections (Ceftazidime, Cef…
Published	07/30/2024	DOC for Pseudomonas infections{{c1::Ceftazidime}}
Published	07/30/2024	Indicated for pneumococcus and S. aureus infections{{c1:: Oral 3rd Gen Cephalosporins (cefixime, cefdinir, ceftibuten, cefpodoxime proxetil)}}
Published	07/30/2024	Cefixime or Cefpodoxime: less effective but better tasting{{c1::Cefixime}}
Published	07/30/2024	Cefixime or Cefpodoxime: more effective but has a worse taste{{c1::Cefpodoxime}}
Published	07/30/2024	Generation of cephalosporins that is:Used in the treatment of febrile neutropenia{{c1::3rd Gen Cephalosporins}}
Published	07/30/2024	T/F: Most cephalosporins are excreted renally.{{c1::T (except cefoperazone and ceftriaxone, which is biliary)}}
Published	07/30/2024	T/F: ESBL-producing strains are resistant to 3rd generationcephalosporins, thus ineffective.{{c1::T}}
Published	07/30/2024	T/F: Serratia, Providencia, and Citrobacter may have resistanceagainst cephalosporins due to a chromosomally encodedcephalosporinase{{c1::T}}
Published	07/30/2024	Give example of 4th gen cephalosporin.{{c1::Cefepime}}
Published	07/30/2024	Give indications of 4th gen cephalosporins.{{c1::Enterobacter infectionsNeisseria and Haemophilus infectionsMeningitis due to good CSF penetration*Not…
Published	07/30/2024	Give example of 5th gen cephalosporins.{{c1::Ceftaroline}}
Published	07/30/2024	T/F:5th gen cephalosporins are not active against AmpC or ESBL-producing organisms {{c1::T}}
Published	07/30/2024	Cephalosporin currently approved for the treatment of skin andsoft tissue infections and community-acquired pneumonia(CAP){{c1::Ceftaroline }}
Published	07/30/2024	T/F: If a patient complains of anaphylaxis to penicillin, thepatient receives penicillin and was brought to the ER:laryngospasm, hypotension, and life…
Published	07/30/2024	Cephalosporins that cause hypothrombinemia and bleeding disorders:{{c1::Methylthiotetrazole group-containing cephalosporins (Cefamandole,Cefmetazole, …
Published	07/30/2024	Cephalosporins that cause disulfiram-like reactionss:{{c1::Methylthiotetrazole ring-containing cephalosporin (Cefoperazone)}}
Published	07/30/2024	Cephalosporins that cause rash and arthritis (serum sickness), especially in children:{{c1::Cefaclor}}
Published	07/30/2024	Cephalosporins that cause bile sludging and pseudocholelithiasis:{{c1::Ceftriaxone}}
Published	07/30/2024	Spectrum of activity: limited to aerobic gram-negativebacteria including E. coli, Serratia, Proteus, Salmonella,Haemophilus, Klebsiella (including P. …
Published	07/30/2024	{{c1::Aztreonam}}Has structural similarities to CeftazidimeGram negative spectrum is similar to that of thethird-generation cephalosporins and aminogl…
Published	07/30/2024	T/F: Aztreonam is effect in combatting ESBL.{{c1::F}}
Published	07/30/2024	T/F: Aztreonam can be used in treating meningitis due to its ability to penetrate well into the CSF.{{c1::T}}
Published	07/30/2024	T/F: Pencillin-allergic patients can tolerate aztreonam without reaction.{{c1::T}}
Published	07/30/2024	monobactams (aztreonam) ADE:{{c1::Elevations of serum aminotransferaseRisk of allergic skin rashes (even anaphylaxis): more likely in patients allergi…
Status	Last Update	Fields